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Computer assisted diagnosis in digital pathology is becoming ubiquitous as it can provide more efficient and objective healthcare diagnostics. Recent advances have shown that the convolutional Neural Network (CNN) architectures, a…

Image and Video Processing · Electrical Eng. & Systems 2022-01-05 Sruthi Krishna , Suganthi S. S , Shivsubramani Krishnamoorthy , Arnav Bhavsar

With the remarkable success of representation learning for prediction problems, we have witnessed a rapid expansion of the use of machine learning and deep learning for the analysis of digital pathology and biopsy image patches. However,…

Machine Learning · Computer Science 2024-03-06 David Ahmedt-Aristizabal , Mohammad Ali Armin , Simon Denman , Clinton Fookes , Lars Petersson

In many practical applications, deep neural networks have been typically deployed to operate as a black box predictor. Despite the high amount of work on interpretability and high demand on the reliability of these systems, they typically…

Artificial Intelligence · Computer Science 2020-12-07 Martin Stano , Wanda Benesova , Lukas Samuel Martak

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

We present a novel and hierarchical approach for supervised classification of signals spanning over a fixed graph, reflecting shared properties of the dataset. To this end, we introduce a Convolutional Cluster Pooling layer exploiting a…

Machine Learning · Computer Science 2019-02-14 Angelo Porrello , Davide Abati , Simone Calderara , Rita Cucchiara

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Convolutional Neural Networks (CNNs) compression is crucial to deploying these models in edge devices with limited resources. Existing channel pruning algorithms for CNNs have achieved plenty of success on complex models. They approach the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Alireza Ganjdanesh , Shangqian Gao , Heng Huang

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

Interpreting the prediction mechanism of complex models is currently one of the most important tasks in the machine learning field, especially with layered neural networks, which have achieved high predictive performance with various…

Machine Learning · Statistics 2018-10-04 Chihiro Watanabe

Deep clustering uncovers hidden patterns and groups in complex time series data, yet its opaque decision-making limits use in safety-critical settings. This survey offers a structured overview of explainable deep clustering for time series,…

Machine Learning · Computer Science 2025-10-21 Udo Schlegel , Gabriel Marques Tavares , Thomas Seidl

Clustering is a widely-used data mining tool, which aims to discover partitions of similar items in data. We introduce a new clustering paradigm, \emph{accordant clustering}, which enables the discovery of (predefined) group level insights.…

Machine Learning · Computer Science 2017-04-11 Amit Dhurandhar , Margareta Ackerman , Xiang Wang

A particular class of Explainable AI (XAI) methods provide saliency maps to highlight part of the image a Convolutional Neural Network (CNN) model looks at to classify the image as a way to explain its working. These methods provide an…

Machine Learning · Computer Science 2021-06-25 Sam Zabdiel Sunder Samuel , Vidhya Kamakshi , Namrata Lodhi , Narayanan C Krishnan

Cancer genomes exhibit a large number of different alterations that affect many genes in a diverse manner. It is widely believed that these alterations follow combinatorial patterns that have a strong connection with the underlying…

Machine Learning · Computer Science 2016-01-26 Jack P. Hou , Amin Emad , Gregory J. Puleo , Jian Ma , Olgica Milenkovic

Accurate diagnosis of breast cancer in histopathology images is challenging due to the heterogeneity of cancer cell growth as well as of a variety of benign breast tissue proliferative lesions. In this paper, we propose a practical and…

Computer Vision and Pattern Recognition · Computer Science 2020-05-06 Xingyu Li , Marko Radulovic , Ksenija Kanjer , Konstantinos N. Plataniotis

Worldwide, prostate cancer is one of the main cancers affecting men. The final diagnosis of prostate cancer is based on the visual detection of Gleason patterns in prostate biopsy by pathologists. Computer-aided-diagnosis systems allow to…

Computer Vision and Pattern Recognition · Computer Science 2020-05-26 Amartya Kalapahar , Julio Silva-Rodríguez , Adrián Colomer , Fernando López-Mir , Valery Naranjo

Mode-based clustering methods define clusters to be the basins of attraction of the modes of a density estimate. The most common version is mean shift clus- tering which uses a gradient ascent algorithm to find the basins. Rodriguez and…

Methodology · Statistics 2018-05-14 Isabella Verdinelli , Larry Wasserman

An important part of breast cancer staging is the assessment of the sentinel axillary node for early signs of tumor spreading. However, this assessment by pathologists is not always easy and retrospective surveys often requalify the status…

Quantitative Methods · Quantitative Biology 2024-04-30 Eric Bonnet

The community structure of complex networks reveals both their organization and hidden relationships among their constituents. Most community detection methods currently available are not deterministic, and their results typically depend on…

Physics and Society · Physics 2012-03-29 Andrea Lancichinetti , Santo Fortunato

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur