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Most classification methods are based on the assumption that data conforms to a stationary distribution. The machine learning domain currently suffers from a lack of classification techniques that are able to detect the occurrence of a…

Machine Learning · Statistics 2012-01-05 Alzennyr Da Silva , Yves Lechevallier , Fabrice Rossi , Francisco De A. T. De Carvahlo

Security researchers grapple with the surge of malicious files, necessitating swift identification and classification of malware strains for effective protection. Visual classifiers and in particular Convolutional Neural Networks (CNNs)…

Cryptography and Security · Computer Science 2025-03-05 Matteo Brosolo , Vinod Puthuvath , Mauro Conti

Interpretable clustering algorithms aim to group similar data points while explaining the obtained groups to support knowledge discovery and pattern recognition tasks. While most approaches to interpretable clustering construct clusters…

Machine Learning · Computer Science 2024-08-27 Nakul Upadhya , Eldan Cohen

Deep learning has recently gained popularity in digital pathology due to its high prediction quality. However, the medical domain requires explanation and insight for a better understanding beyond standard quantitative performance…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Miriam Hägele , Philipp Seegerer , Sebastian Lapuschkin , Michael Bockmayr , Wojciech Samek , Frederick Klauschen , Klaus-Robert Müller , Alexander Binder

We propose a method for gene expression based analysis of cancer phenotypes incorporating network biology knowledge through unsupervised construction of computational graphs. The structural construction of the computational graphs is driven…

Molecular Networks · Quantitative Biology 2020-10-02 Paul Scherer , Maja Trȩbacz , Nikola Simidjievski , Zohreh Shams , Helena Andres Terre , Pietro Liò , Mateja Jamnik

Prostate cancer is one of the most common causes of cancer deaths in men. There is a growing demand for noninvasively and accurately diagnostic methods that facilitate the current standard prostate cancer risk assessment in clinical…

Image and Video Processing · Electrical Eng. & Systems 2021-12-30 Ping-Chang Lin , Teodora Szasz , Hakizumwami B. Runesha

NLP-based computer vision models, particularly vision transformers, have been shown to outperform CNN models in many imaging tasks. However, most digital pathology artificial-intelligence models are based on CNN architectures, probably…

Computation and Language · Computer Science 2023-02-22 Min Cen , Xingyu Li , Bangwei Guo , Jitendra Jonnagaddala , Hong Zhang , Xu Steven Xu

Multi-centre colonoscopy images from various medical centres exhibit distinct complicating factors and overlays that impact the image content, contingent on the specific acquisition centre. Existing Deep Segmentation networks struggle to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-31 Valentina Corbetta , Regina Beets-Tan , Wilson Silva

Early detection is crucial for successful cancer treatment and increasing survivability rates, particularly in the most common forms. Ten different cancers have been identified in most of these advances that effectively use CNNs…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Hossein Molaeian , Kaveh Karamjani , Sina Teimouri , Saeed Roshani , Sobhan Roshani

Clustering of proteins is of interest in cancer cell biology. This article proposes a hierarchical Bayesian model for protein (variable) clustering hinging on correlation structure. Starting from a multivariate normal likelihood, we enforce…

Computation · Statistics 2022-02-09 Riddhi Pratim Ghosh , Arnab Kumar Maity , Mohsen Pourahmadi , Bani K. Mallick

We consider the problem of image classification for the purpose of aiding doctors in dermatological diagnosis. Dermatological diagnosis poses two major challenges for standard off-the-shelf techniques: First, the data distribution is…

Computer Vision and Pattern Recognition · Computer Science 2018-11-08 Viraj Prabhu , Anitha Kannan , Murali Ravuri , Manish Chablani , David Sontag , Xavier Amatriain

In many fields, researchers are interested in large and complex biological processes. Two important examples are gene expression and DNA methylation in genetics. One key problem is to identify aberrant patterns of these processes and…

Applications · Statistics 2012-10-03 Matthias Kormaksson , James G. Booth , Maria E. Figueroa , Ari Melnick

Precision medicine is an approach for disease treatment that defines treatment strategies based on the individual characteristics of the patients. Motivated by an open problem in cancer genomics, we develop a novel model that flexibly…

Methodology · Statistics 2023-09-04 Matteo Pedone , Raffaele Argiento , Francesco C. Stingo

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal

In recent years, there has been a significant surge in malware attacks, necessitating more advanced preventive measures and remedial strategies. While several successful AI-based malware classification approaches exist categorized into…

Cryptography and Security · Computer Science 2024-04-22 Quincy Card , Daniel Simpson , Kshitiz Aryal , Maanak Gupta , Sheikh Rabiul Islam

In this paper, we present a novel method to automatically classify medical images that learns and leverages weak causal signals in the image. Our framework consists of a convolutional neural network backbone and a causality-extractor module…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Gianluca Carloni , Eva Pachetti , Sara Colantonio

Until recently obtaining data on populations of networks was typically rare. However, with the advancement of automatic monitoring devices and the growing social and scientific interest in networks, such data has become more widely…

Methodology · Statistics 2020-01-22 Mirko Signorelli , Ernst Wit

We propose a new model for digital pathology segmentation, based on the observation that histopathology images are inherently symmetric under rotation and reflection. Utilizing recent findings on rotation equivariant CNNs, the proposed…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Bastiaan S. Veeling , Jasper Linmans , Jim Winkens , Taco Cohen , Max Welling

We present an approach for analyzing grouping information contained within a neural network's activations, permitting extraction of spatial layout and semantic segmentation from the behavior of large pre-trained vision models. Unlike prior…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Xiao Zhang , David Yunis , Michael Maire