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Generative models of graphs based on discrete Denoising Diffusion Probabilistic Models (DDPMs) offer a principled approach to molecular generation by systematically removing structural noise through iterative atom and bond adjustments.…

Machine Learning · Computer Science 2025-11-03 Matteo Ninniri , Marco Podda , Davide Bacciu

Exploring the vast composition space of multi-component alloys presents a challenging task for both \textit{ab initio} (first principles) and experimental methods due to the time-consuming procedures involved. This ultimately impedes the…

Diffusion distillation methods aim to compress the diffusion models into efficient one-step generators while trying to preserve quality. Among them, Distribution Matching Distillation (DMD) offers a suitable framework for training…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Denis Rakitin , Ivan Shchekotov , Dmitry Vetrov

Recent advances in generative modeling have shown significant promise in designing novel periodic crystal structures. Existing approaches typically rely on either large language models (LLMs) or equivariant denoising models, each with…

Machine Learning · Computer Science 2025-10-28 Subhojyoti Khastagir , Kishalay Das , Pawan Goyal , Seung-Cheol Lee , Satadeep Bhattacharjee , Niloy Ganguly

Efficient exploration of the vast chemical space is a fundamental challenge in materials design and discovery, particularly for designing functional inorganic crystalline materials with targeted properties. Diffusion-based generative models…

Materials Science · Physics 2026-03-20 Sourav Mal , Nehad Ahmed , Junaid Jami , Subhankar Mishra , Prasenjit Sen

Recent years have witnessed the success of diffusion models in image customization tasks. However, existing mask-guided human erasing methods still struggle in complex scenarios such as human-human occlusion, human-object entanglement, and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-17 Jinghan Yu , Junhao Xiao , Zhiyuan Ma , Yue Ma , Kaiqi Liu , Yuhan Wang , Daizong Liu , Xianghao Meng , Jianjun Li

Large video diffusion and flow models have achieved remarkable success in high-quality video generation, but their use in real-time interactive applications remains limited due to their inefficient multi-step sampling process. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-16 Weili Nie , Julius Berner , Nanye Ma , Chao Liu , Saining Xie , Arash Vahdat

Generative diffusion models have achieved remarkable success in producing high-quality images. However, these models typically operate in continuous intensity spaces, diffusing independently across pixels and color channels. As a result,…

Graphics · Computer Science 2025-05-20 Javier E. Santos , Agnese Marcato , Roman Colman , Nicholas Lubbers , Yen Ting Lin

Beyond high-fidelity image synthesis, diffusion models have recently exhibited promising results in dense visual perception tasks. However, most existing work treats diffusion models as a standalone component for perception tasks, employing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Shuhong Zheng , Zhipeng Bao , Ruoyu Zhao , Martial Hebert , Yu-Xiong Wang

Modern successes of diffusion models in learning complex, high-dimensional data distributions are attributed, in part, to their capability to construct diffusion processes with analytic transition kernels and score functions. The…

Machine Learning · Statistics 2024-03-01 Guan-Horng Liu , Tianrong Chen , Evangelos A. Theodorou , Molei Tao

Diffusion models have recently shown great promise for generative modeling, outperforming GANs on perceptual quality and autoregressive models at density estimation. A remaining downside is their slow sampling time: generating high quality…

Machine Learning · Computer Science 2022-06-08 Tim Salimans , Jonathan Ho

Discrete diffusion models form a powerful class of generative models across diverse domains, including text and graphs. However, existing approaches face fundamental limitations. Masked diffusion models suffer from irreversible errors due…

Machine Learning · Computer Science 2026-04-21 Marcel Kollovieh , Sirine Ayadi , Stephan Günnemann

The paradigm shift toward structure-driven molecule generation has been propelled by advances in deep generative models, such as variational auto-encoders and diffusion models. However, these generative models for molecular design remain…

Machine Learning · Computer Science 2026-04-17 Peidong Liu , Wenbo Zhang , Wei Ju , Jiancheng Lv , Xianggen Liu

While diffusion models can learn complex distributions, sampling requires a computationally expensive iterative process. Existing distillation methods enable efficient sampling, but have notable limitations, such as performance degradation…

Machine Learning · Computer Science 2024-12-09 Sirui Xie , Zhisheng Xiao , Diederik P Kingma , Tingbo Hou , Ying Nian Wu , Kevin Patrick Murphy , Tim Salimans , Ben Poole , Ruiqi Gao

Diffusion models have demonstrated exceptional capabilities in generating high-fidelity images but typically suffer from inefficient sampling. Many solver designs and noise scheduling strategies have been proposed to dramatically improve…

Machine Learning · Statistics 2025-10-01 Tianrong Chen , Huangjie Zheng , David Berthelot , Jiatao Gu , Josh Susskind , Shuangfei Zhai

Diffusion models have attained remarkable success in the domains of image generation and editing. It is widely recognized that employing larger inversion and denoising steps in diffusion model leads to improved image reconstruction quality.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Chen Hou , Guoqiang Wei , Zhibo Chen

Discrete diffusion models, like continuous diffusion models, generate high-quality samples by gradually undoing noise applied to datapoints with a Markov process. Gradual generation in theory comes with many conceptual benefits; for…

Machine Learning · Computer Science 2025-09-30 Alan N. Amin , Nate Gruver , Andrew Gordon Wilson

Generative modeling within constrained sets is essential for scientific and engineering applications involving physical, geometric, or safety requirements (e.g., molecular generation, robotics). We present a unified framework for…

Machine Learning · Computer Science 2026-04-21 Kijung Jeon , Michael Muehlebach , Molei Tao

We present a generative modeling framework for atomistic systems that combines score-based diffusion for atomic positions with a novel continuous-time discrete diffusion process for atomic types. This approach enables flexible and…

Computational Physics · Physics 2025-09-17 Nikolaj Rønne , Bjørk Hammer

Recent advancements in the realm of deep generative models focus on generating samples that satisfy multiple desired properties. However, prevalent approaches optimize these property functions independently, thus omitting the trade-offs…

Machine Learning · Computer Science 2024-07-08 Yinghua Yao , Yuangang Pan , Jing Li , Ivor Tsang , Xin Yao