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Electroencephalography (EEG) provides a non-invasive, highly accessible, and cost-effective approach for detecting Alzheimer's disease (AD). However, existing methods, whether based on handcrafted feature engineering or standard deep…
Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…
Resting state functional magnetic resonance images (fMRI) are commonly used for classification of patients as having Alzheimer's disease (AD), mild cognitive impairment (MCI), or being cognitive normal (CN). Most methods use time-series…
The study's objective is to explore the distinctions in the functional brain network connectivity between Alzheimer's Disease (AD) patients and normal controls using Functional Magnetic Resonance Imaging (fMRI). The study included 590…
Alzheimer's Disease is a progressive neurological disorder that is one of the most common forms of dementia. It leads to a decline in memory, reasoning ability, and behavior, especially in older people. The cause of Alzheimer's Disease is…
Dynamic functional connectivity (DFC) analysis involves measuring correlated neural activity over time across multiple brain regions. Significant regional correlations among neural signals, such as those obtained from resting-state…
Background: Although convolutional neural networks (CNN) achieve high diagnostic accuracy for detecting Alzheimer's disease (AD) dementia based on magnetic resonance imaging (MRI) scans, they are not yet applied in clinical routine. One…
Recent analyses combining advanced theoretical techniques and high-quality data from thousands of simultaneously recorded neurons provide strong support for the hypothesis that neural dynamics operate near the edge of instability across…
Alzheimers disease (AD) is a progressive disorder that affects cognitive brain functions and starts many years before its clinical manifestations. A biomarker that provides a quantitative measure of changes in the brain due to AD in the…
Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…
The incidence of Alzheimer's disease (AD) and other forms of dementia is increasing in most western countries. For a precise and early diagnosis, several examination modalities exist, among them single-photon emission computed tomography…
We exploit altered patterns in brain functional connectivity as features for automatic discriminative analysis of neuropsychiatric patients. Deep learning methods have been introduced to functional network classification only very recently…
Alzheimer's Disease (AD) is one of the most concerned neurodegenerative diseases. In the last decade, studies on AD diagnosis attached great significance to artificial intelligence (AI)-based diagnostic algorithms. Among the diverse…
Alzheimer's disease (AD) is a neurodegenerative disorder affecting millions worldwide, necessitating early and accurate diagnosis for optimal patient management. In recent years, advancements in deep learning have shown remarkable potential…
Some evidence suggests that people with autism spectrum disorder exhibit patterns of brain functional dysconnectivity relative to their typically developing peers, but specific findings have yet to be replicated. To facilitate this…
Functional Magnetic Resonance Imaging (fMRI) is an imaging technique widely used to study human brain activity. fMRI signals in areas across the brain transiently synchronise and desynchronise their activity in a highly structured manner,…
Cross-frequency interactions are fundamental brain mechanisms for integrating information across temporal scales. However, accurate identification of these couplings is hindered by complex multi-frequency nonlinearities and by spurious,…
Alzheimer's disease (AD) is an irreversible brain disease that can dramatically reduce quality of life, most commonly manifesting in older adults and eventually leading to the need for full-time care. Early detection is fundamental to…
Several methods have been developed to extract information from electroencephalograms (EEG). One of them is Phase-Amplitude Coupling (PAC) which is a type of Cross-Frequency Coupling (CFC) method, consisting in measure the synchronization…
Background and Objective: The connection between depression and autonomous nervous system (ANS) is well documented in scientific literature. Heart rate variability (HRV) is a rich source of information for studying the dynamics of this…