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Diagnosing and treating skin diseases require advanced visual skills across domains and the ability to synthesize information from multiple imaging modalities. While current deep learning models excel at specific tasks like skin cancer…

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

A major focus of clinical imaging workflow is disease diagnosis and management, leading to medical imaging datasets strongly tied to specific clinical objectives. This scenario has led to the prevailing practice of developing task-specific…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Yunhe Gao , Zhuowei Li , Di Liu , Mu Zhou , Shaoting Zhang , Dimitris N. Metaxas

Obtaining large pre-trained models that can be fine-tuned to new tasks with limited annotated samples has remained an open challenge for medical imaging data. While pre-trained deep networks on ImageNet and vision-language foundation models…

Computer Vision and Pattern Recognition · Computer Science 2023-11-21 Duy M. H. Nguyen , Hoang Nguyen , Nghiem T. Diep , Tan N. Pham , Tri Cao , Binh T. Nguyen , Paul Swoboda , Nhat Ho , Shadi Albarqouni , Pengtao Xie , Daniel Sonntag , Mathias Niepert

Recent advancements in medical Large Language Models (LLMs) have showcased their powerful reasoning and diagnostic capabilities. Despite their success, current unified multimodal medical LLMs face limitations in knowledge update costs,…

Computation and Language · Computer Science 2025-06-25 Yucheng Zhou , Lingran Song , Jianbing Shen

Natural Language Explanations (NLE) aim at supplementing the prediction of a model with human-friendly natural text. Existing NLE approaches involve training separate models for each downstream task. In this work, we propose Uni-NLX, a…

Computer Vision and Pattern Recognition · Computer Science 2023-09-20 Fawaz Sammani , Nikos Deligiannis

Digital pathology in the form of whole-slide-imaging has been used to support diagnostic consultation through telepathology. Previous studies have mostly addressed the technical aspects of telepathology and general pathology consultation.…

Human-Computer Interaction · Computer Science 2024-12-17 Uyen Ly , Quang Nguyen , Dang Nguyen , Tu Thai , Binh Le , Duong Gion , Alexander Banerjee , Brenda Mai , Amer Wahed , Andy Nguyen

Multimodal large language models (MLLMs) have emerged as powerful tools for computational pathology, offering unprecedented opportunities to integrate pathological images with language context for comprehensive diagnostic analysis. These…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Zhe Xu , Ziyi Liu , Junlin Hou , Jiabo Ma , Cheng Jin , Yihui Wang , Zhixuan Chen , Zhengyu Zhang , Fuxiang Huang , Zhengrui Guo , Fengtao Zhou , Yingxue Xu , Xi Wang , Ronald Cheong Kin Chan , Li Liang , Hao Chen

Ultrasound images vary widely across scanners, operators, and anatomical targets, which often causes models trained in one setting to generalize poorly to new hospitals and clinical conditions. The Foundation Model Challenge for Ultrasound…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Ufaq Khan , L. D. M. S. Sai Teja , Ayuba Shakiru , Mai A. Shaaban , Yutong Xie , Muhammad Bilal , Muhammad Haris Khan

The stunning qualitative improvement of recent text-to-image models has led to their widespread attention and adoption. However, we lack a comprehensive quantitative understanding of their capabilities and risks. To fill this gap, we…

Molecular Dynamics (MD) simulations are essential for understanding the atomic-level behavior of molecular systems, giving insights into their transitions and interactions. However, classical MD techniques are limited by the trade-off…

Biomolecules · Quantitative Biology 2026-04-21 Ziyang Yu , Wenbing Huang , Yang Liu

Self-supervised vision models have achieved notable success in digital pathology. However, their domain-agnostic transformer architectures are not originally designed to account for fundamental biological elements of histopathology images,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Sevda Öğüt , Cédric Vincent-Cuaz , Natalia Dubljevic , Carlos Hurtado , Vaishnavi Subramanian , Pascal Frossard , Dorina Thanou

Visual impairment represents a major global health challenge, with multimodal imaging providing complementary information that is essential for accurate ophthalmic diagnosis. This comprehensive survey systematically reviews the latest…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Xiaoling Luo , Ruli Zheng , Qiaojian Zheng , Zibo Du , Shuo Yang , Meidan Ding , Qihao Xu , Chengliang Liu , Linlin Shen

Background and Objective: To address the inability of single-model architectures to perform simultaneous analysis of complex glomerular ultrastructures, we developed Glo-UMF, a unified multi-model framework integrating segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Zhentai Zhang , Danyi Weng , Guibin Zhang , Xiang Chen , Kaixing Long , Jian Geng , Yanmeng Lu , Lei Zhang , Zhitao Zhou , Lei Cao

Digital pathology has recently been revolutionized by advancements in artificial intelligence, deep learning, and high-performance computing. With its advanced tools, digital pathology can help improve and speed up the diagnostic process,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Mohamed Elmanna , Ahmed Elsafty , Yomna Ahmed , Muhammad Rushdi , Ahmed Morsy

As Large Language Models increasingly power role-playing applications, simulating patients has become a valuable tool for training counselors and scaling therapeutic assessment. However, prior work is fragmented: existing approaches rely on…

Computation and Language · Computer Science 2026-02-13 Sahand Sabour , TszYam NG , Minlie Huang

Computer vision models are increasingly capable of classifying ovarian epithelial cancer subtypes, but they differ from pathologists by processing small tissue patches at a single resolution. Multi-resolution graph models leverage the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Jack Breen , Katie Allen , Kieran Zucker , Nicolas M. Orsi , Nishant Ravikumar

Artificial intelligence (AI)-enabled diagnostics in maxillofacial pathology require structured, high-quality multimodal datasets. However, existing resources provide limited ameloblastoma coverage and lack the format consistency needed for…

Artificial Intelligence · Computer Science 2026-02-06 Ajo Babu George , Anna Mariam John , Athul Anoop , Balu Bhasuran

Digital pathology is not only one of the most promising fields of diagnostic medicine, but at the same time a hot topic for fundamental research. Digital pathology is not just the transfer of histopathological slides into digital…

Artificial Intelligence · Computer Science 2017-12-20 Andreas Holzinger , Bernd Malle , Peter Kieseberg , Peter M. Roth , Heimo Müller , Robert Reihs , Kurt Zatloukal