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Histopathology foundation models (HFMs), pretrained on large-scale cancer datasets, have advanced computational pathology. However, their applicability to non-cancerous chronic kidney disease remains underexplored, despite coexistence of…

We propose Unified-IO, a model that performs a large variety of AI tasks spanning classical computer vision tasks, including pose estimation, object detection, depth estimation and image generation, vision-and-language tasks such as region…

Computer Vision and Pattern Recognition · Computer Science 2022-10-06 Jiasen Lu , Christopher Clark , Rowan Zellers , Roozbeh Mottaghi , Aniruddha Kembhavi

Human image editing includes tasks like changing a person's pose, their clothing, or editing the image according to a text prompt. However, prior work often tackles these tasks separately, overlooking the benefit of mutual reinforcement…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Nannan Li , Qing Liu , Krishna Kumar Singh , Yilin Wang , Jianming Zhang , Bryan A. Plummer , Zhe Lin

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Handwritten Mathematical Expression Recognition (HMER) remains a persistent challenge in Optical Character Recognition (OCR) due to the inherent freedom of symbol layouts and variability in handwriting styles. Prior methods have faced…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Yu Li , Jin Jiang , Jianhua Zhu , Shuai Peng , Baole Wei , Yuxuan Zhou , Liangcai Gao

In Computational Pathology (CPath), the introduction of Vision-Language Models (VLMs) has opened new avenues for research, focusing primarily on aligning image-text pairs at a single magnification level. However, this approach might not be…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Shahad Albastaki , Anabia Sohail , Iyyakutti Iyappan Ganapathi , Basit Alawode , Asim Khan , Sajid Javed , Naoufel Werghi , Mohammed Bennamoun , Arif Mahmood

By leveraging large amounts of product data collected across hundreds of live e-commerce websites, we construct 1000 unique classification tasks that share similarly-structured input data, comprised of both text and images. These…

Artificial Intelligence · Computer Science 2021-07-29 Cameron R. Wolfe , Keld T. Lundgaard

Recent advancements in multi-modal large language models (MLLMs) have led to substantial improvements in visual understanding, primarily driven by sophisticated modality alignment strategies. However, predominant approaches prioritize…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Jinjin Xu , Liwu Xu , Yuzhe Yang , Xiang Li , Fanyi Wang , Yanchun Xie , Yi-Jie Huang , Yaqian Li

The recent advances in neural language models have also been successfully applied to the field of chemistry, offering generative solutions for classical problems in molecular design and synthesis planning. These new methods have the…

Machine Learning · Computer Science 2023-05-19 Dimitrios Christofidellis , Giorgio Giannone , Jannis Born , Ole Winther , Teodoro Laino , Matteo Manica

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li

Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the…

Machine Learning · Computer Science 2023-11-22 Bhavya Mehta , Nirmit Deliwala , Madhav Chandane

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Unified Multimodal Models (UMMs) offer powerful cross-modality capabilities but introduce new safety risks not observed in single-task models. Despite their emergence, existing safety benchmarks remain fragmented across tasks and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Segyu Lee , Boryeong Cho , Hojung Jung , Seokhyun An , Juhyeong Kim , Jaehyun Kwak , Yongjin Yang , Sangwon Jang , Youngrok Park , Wonjun Chang , Se-Young Yun

With the recent availability of Electronic Health Records (EHR) and great opportunities they offer for advancing medical informatics, there has been growing interest in mining EHR for improving quality of care. Disease diagnosis due to its…

Artificial Intelligence · Computer Science 2018-04-24 Anahita Hosseini , Ting Chen , Wenjun Wu , Yizhou Sun , Majid Sarrafzadeh

Automatic mammogram classification and mass segmentation play a critical role in a computer-aided mammogram screening system. In this work, we present a unified mammogram analysis framework for both whole-mammogram classification and…

Computer Vision and Pattern Recognition · Computer Science 2018-09-03 Rongzhao Zhang , Han Zhang , Albert C. S. Chung

Pathological diagnosis remains the definitive standard for identifying tumors. The rise of multimodal large models has simplified the process of integrating image analysis with textual descriptions. Despite this advancement, the substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Xiaomin Wu , Rui Xu , Pengchen Wei , Wenkang Qin , Peixiang Huang , Ziheng Li , Lin Luo

Designing effective data manipulation methods is a long standing problem in data lakes. Traditional methods, which rely on rules or machine learning models, require extensive human efforts on training data collection and tuning models.…

Artificial Intelligence · Computer Science 2024-05-13 Yichen Qian , Yongyi He , Rong Zhu , Jintao Huang , Zhijian Ma , Haibin Wang , Yaohua Wang , Xiuyu Sun , Defu Lian , Bolin Ding , Jingren Zhou

Histopathology evaluation of tissue specimens through microscopic examination is essential for accurate disease diagnosis and prognosis. However, traditional manual analysis by specially trained pathologists is time-consuming,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-12 Fuyao Chen , Yuexi Du , Tal Zeevi , Nicha C. Dvornek , John A. Onofrey

IMPORTANCE: Modern ultrasound systems are universal diagnostic tools capable of imaging the entire body. However, current AI solutions remain fragmented into single-task tools. This critical gap between hardware versatility and software…

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao