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Single-cell RNA sequencing (scRNA-seq) reveals cell heterogeneity, with cell clustering playing a key role in identifying cell types and marker genes. Recent advances, especially graph neural networks (GNNs)-based methods, have…

Genomics · Quantitative Biology 2025-10-03 Ping Xu , Zhiyuan Ning , Pengjiang Li , Wenhao Liu , Pengyang Wang , Jiaxu Cui , Yuanchun Zhou , Pengfei Wang

Real-world networks are composed of diverse interacting and evolving entities, while most of existing researches simply characterize them as particular static networks, without consideration of the evolution trend in dynamic networks.…

Social and Information Networks · Computer Science 2020-06-16 Yu Xie , Chunyi Li , Bin Yu , Chen Zhang , Zhouhua Tang

Deep learning has revolutionized many industries by enabling models to automatically learn complex patterns from raw data, reducing dependence on manual feature engineering. However, deep learning algorithms are sensitive to input data, and…

Machine Learning · Computer Science 2025-07-21 Mert Sehri , Zehui Hua , Francisco de Assis Boldt , Patrick Dumond

Dataset distillation is a newly emerging task that synthesizes a small-size dataset used in training deep neural networks (DNNs) for reducing data storage and model training costs. The synthetic datasets are expected to capture the essence…

Computer Vision and Pattern Recognition · Computer Science 2023-11-06 Jiawei Du , Qin Shi , Joey Tianyi Zhou

We introduce Active Tuning, a novel paradigm for optimizing the internal dynamics of recurrent neural networks (RNNs) on the fly. In contrast to the conventional sequence-to-sequence mapping scheme, Active Tuning decouples the RNN's…

Machine Learning · Computer Science 2020-11-26 Sebastian Otte , Matthias Karlbauer , Martin V. Butz

Time-series single-cell RNA-sequencing (scRNA-seq) datasets offer unprecedented insights into the dynamics and heterogeneity of cellular systems. These systems exhibit multiscale collective behaviors driven by intricate intracellular gene…

Quantitative Methods · Quantitative Biology 2025-05-23 Qi Jiang , Lei Zhang , Longquan Li , Lin Wan

Deep neural networks, albeit their great success on feature learning in various computer vision tasks, are usually considered as impractical for online visual tracking because they require very long training time and a large number of…

Computer Vision and Pattern Recognition · Computer Science 2016-05-04 Hanxi Li , Yi Li , Fatih Porikli

We present the use of single-cell entropy (scEntropy) to measure the order of the cellular transcriptome profile from single-cell RNA-seq data, which leads to a method of unsupervised cell type classification through scEntropy followed by…

Quantitative Methods · Quantitative Biology 2020-02-18 Jingxin Liu , You Song , Jinzhi Lei

In many real-world settings--e.g., single-cell RNA sequencing, mobility sensing, and environmental monitoring--data are observed only as temporally aggregated snapshots collected over finite time windows, often with noisy or uncertain…

Machine Learning · Computer Science 2026-05-25 Keisuke Kawano , Takuro Kutsuna , Naoki Hayashi , Yasushi Esaki , Hidenori Tanaka

The spatial location of cells within tissues and organs is crucial for the manifestation of their specific functions.Spatial transcriptomics technology enables comprehensive measurement of the gene expression patterns in tissues while…

Quantitative Methods · Quantitative Biology 2024-07-12 Shuailin Xue , Fangfang Zhu , Changmiao Wang , Wenwen Min

Embedding large graphs in low dimensional spaces has recently attracted significant interest due to its wide applications such as graph visualization, link prediction and node classification. Existing methods focus on computing the…

Social and Information Networks · Computer Science 2018-05-30 Palash Goyal , Nitin Kamra , Xinran He , Yan Liu

Achieving optimal semantic segmentation with frame-based vision sensors poses significant challenges for real-time systems like UAVs and self-driving cars, which require rapid and precise processing. Traditional frame-based methods often…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 D. Hareb , J. Martinet , B. Miramond

Diffusion models have become the foundation of modern generative systems, with most research focusing primarily on improving generation efficiency and output quality. The timestep embedding component is a crucial part of the diffusion…

Machine Learning · Computer Science 2026-05-05 An Huang , Junggab Son , Zuobin Xiong

Spatial transcriptomics (ST) is an emerging technology that enables researchers to investigate the molecular relationships underlying tissue morphology. However, acquiring ST data remains prohibitively expensive, and traditional fixed-grid…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Siqi Lu , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yalin Zheng , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

DNA is a promising medium for digital information storage for its exceptional density and durability. While prior studies advanced coding theory, workflow design, and simulation tools, challenges such as synthesis costs, sequencing errors,…

Emerging Technologies · Computer Science 2025-10-06 Rakesh Thakur , Lavanya Singh , Yashika , Manomay Bundawala , Aruna Kumar

Single-cell data provide high-dimensional measurements of the transcriptional states of cells, but extracting insights into the regulatory functions of genes, particularly identifying transcriptional mechanisms affected by biological…

Molecular Networks · Quantitative Biology 2025-03-27 Paul Bertin , Joseph D. Viviano , Alejandro Tejada-Lapuerta , Weixu Wang , Stefan Bauer , Fabian J. Theis , Yoshua Bengio

Tracking cells in time-lapse videos is an essential technique for monitoring cell population dynamics at a single-cell level. Current methods for cell tracking are developed on videos with mostly single, constant signals and do not detect…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Florian Bürger , Martim Dias Gomes , Nica Gutu , Adrián E. Granada , Noémie Moreau , Katarzyna Bozek

Microscopy imaging plays a vital role in understanding many biological processes in development and disease. The recent advances in automation of microscopes and development of methods and markers for live cell imaging has led to rapid…

Computer Vision and Pattern Recognition · Computer Science 2017-05-10 Saad Ullah Akram , Juho Kannala , Lauri Eklund , Janne Heikkilä

Increased attention has been paid over the last four years to dynamic network embedding. Existing dynamic embedding methods, however, consider the problem as limited to the evolution of a topology over a sequence of global, discrete states.…

Machine Learning · Computer Science 2021-11-23 David Bayani

Recent technological advances in cutting-edge ultrasensitive fluorescence microscopy have allowed single-molecule imaging experiments in living cells across all three domains of life to become commonplace. Single-molecule live-cell data is…

Biomolecules · Quantitative Biology 2015-04-15 Mark Leake