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With histograms as its foundation, we develop Categorical Exploratory Data Analysis (CEDA) under the extreme-$K$ sample problem, and illustrate its universal applicability through four 1D categorical datasets. Given a sizable $K$, CEDA's…
Modern clustering approaches often trade interpretability for performance, particularly in deep learning-based methods. We present Generative Kernel Spectral Clustering (GenKSC), a novel model combining kernel spectral clustering with…
A recent literature in econometrics models unobserved cross-sectional heterogeneity in panel data by assigning each cross-sectional unit a one-dimensional, discrete latent type. Such models have been shown to allow estimation and inference…
Autoencoders have been widely used as a nonlinear tool for data dimensionality reduction. While autoencoders don't utilize the label information, Centroid-Encoders (CE)\cite{ghosh2022supervised} use the class label in their learning…
Observational studies of cluster evolution over moderate redshift ranges (to z ~ 1) are a powerful tool for constraining cosmological parameters, yet a comprehensive knowledge of the properties of these clusters has been hitherto…
Epigenetic alterations have an important role in the development of several types of cancer. Epigenetic studies generate a large amount of data, which makes it essential to develop novel models capable of dealing with large-scale data. In…
A weakly supervised learning based clustering framework is proposed in this paper. As the core of this framework, we introduce a novel multiple instance learning task based on a bag level label called unique class count ($ucc$), which is…
Deep clustering as an important branch of unsupervised representation learning focuses on embedding semantically similar samples into the identical feature space. This core demand inspires the exploration of contrastive learning and…
Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on…
Finding tumour genetic markers is essential to biomedicine due to their relevance for cancer detection and therapy development. In this paper, we explore a recently released dataset of chromosome rearrangements in 2,586 cancer patients,…
Short text clustering is a challenging problem due to its sparseness of text representation. Here we propose a flexible Self-Taught Convolutional neural network framework for Short Text Clustering (dubbed STC^2), which can flexibly and…
The study of genetic variants can help find correlating population groups to identify cohorts that are predisposed to common diseases and explain differences in disease susceptibility and how patients react to drugs. Machine learning…
Unsupervised person re-identification (ReID) aims to train a feature extractor for identity retrieval without exploiting identity labels. Due to the blind trust in imperfect clustering results, the learning is inevitably misled by…
Donor-level disease classification from single-cell RNA sequencing (scRNA-seq) requires strict donor-aware cross-validation: naive pipelines that split cells randomly conflate training and test donors, inflating reported performance through…
Predicting drug responses using genetic and transcriptomic features is crucial for enhancing personalized medicine. In this study, we implemented an ensemble of machine learning algorithms to analyze the correlation between genetic and…
In many situations where the interest lies in identifying clusters one might expect that not all available variables carry information about these groups. Furthermore, data quality (e.g. outliers or missing entries) might present a serious…
The widespread availability of large amounts of genomic data on the SARS-CoV-2 virus, as a result of the COVID-19 pandemic, has created an opportunity for researchers to analyze the disease at a level of detail unlike any virus before it.…
Single-cell RNA-sequencing (scRNA-seq) stands as a powerful tool for deciphering cellular heterogeneity and exploring gene expression profiles at high resolution. However, its high cost renders it impractical for extensive sample cohorts…
The characterization of Tumor MicroEnvironment (TME) is challenging due to its complexity and heterogeneity. Relatively consistent TME characteristics embedded within highly specific tissue features, render them difficult to predict. The…
In this paper, we propose a novel, effective and simpler end-to-end image clustering auto-encoder algorithm: ICAE. The algorithm uses PEDCC (Predefined Evenly-Distributed Class Centroids) as the clustering centers, which ensures the…