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Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Spread through air spaces (STAS) constitutes a novel invasive pattern in lung adenocarcinoma (LUAD), associated with tumor recurrence and diminished survival rates. However, large-scale STAS diagnosis in LUAD remains a labor-intensive…

Computer Vision and Pattern Recognition · Computer Science 2025-08-15 Liangrui Pan , xiaoyu Li , Guang Zhu , Guanting Li , Ruixin Wang , Jiadi Luo , Yaning Yang , Liang qingchun , Shaoliang Peng

Blood cell identification is critical for hematological analysis as it aids physicians in diagnosing various blood-related diseases. In real-world scenarios, blood cell image datasets often present the issues of domain shift and data…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Yongcheng Li , Lingcong Cai , Ying Lu , Xianghua Fu , Xiao Han , Ma Li , Wenxing Lai , Xiangzhong Zhang , Xiaomao Fan

Automated disease classification of radiology images has been emerging as a promising technique to support clinical diagnosis and treatment planning. Unlike generic image classification tasks, a real-world radiology image classification…

Computer Vision and Pattern Recognition · Computer Science 2020-07-22 Congbo Ma , Hu Wang , Steven C. H. Hoi

Oral epithelial dysplasia (OED) is a pre-malignant histopathological diagnosis given to lesions of the oral cavity. Predicting OED grade or whether a case will transition to malignancy is critical for early detection and appropriate…

Image and Video Processing · Electrical Eng. & Systems 2021-09-02 Adam J. Shephard , Simon Graham , R. M. Saad Bashir , Mostafa Jahanifar , Hanya Mahmood , Syed Ali Khurram , Nasir M. Rajpoot

In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Histopathological image analysis is an essential process for the discovery of diseases such as cancer. However, it is challenging to train CNN on whole slide images (WSIs) of gigapixel resolution considering the available memory capacity.…

Image and Video Processing · Electrical Eng. & Systems 2019-10-11 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Masashi Fukayama , Akihiko Yoshizawa , Masanobu Kitagawa , Tatsuya Harada

The recognition of multi-class cell nuclei can significantly facilitate the process of histopathological diagnosis. Numerous pathological datasets are currently available, but their annotations are inconsistent. Most existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-02-21 Junjia Huang , Haofeng Li , Xiang Wan , Guanbin Li

Accurate detection and classification of nuclei in histopathology images are critical for diagnostic and research applications. We present KongNet, a multi-headed deep learning architecture featuring a shared encoder and parallel,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-13 Jiaqi Lv , Esha Sadia Nasir , Kesi Xu , Mostafa Jahanifar , Brinder Singh Chohan , Behnaz Elhaminia , Shan E Ahmed Raza

Histopathology images contain essential information for medical diagnosis and prognosis of cancerous disease. Segmentation of glands in histopathology images is a primary step for analysis and diagnosis of an unhealthy patient. Due to the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Safiyeh Rezaei , Ali Emami , Hamidreza Zarrabi , Shima Rafiei , Kayvan Najarian , Nader Karimi , Shadrokh Samavi , S. M. Reza Soroushmehr

The rapid adoption of transformer-based models in computational pathology has enabled prediction of molecular and clinical biomarkers from H&E whole-slide images, yet interpretability has not kept pace with model complexity. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marco Gustav , Fabian Wolf , Christina Glasner , Nic G. Reitsam , Stefan Schulz , Kira Aschenbroich , Bruno Märkl , Sebastian Foersch , Jakob Nikolas Kather

Tissue-level semantic segmentation is a vital step in computational pathology. Fully-supervised models have already achieved outstanding performance with dense pixel-level annotations. However, drawing such labels on the giga-pixel whole…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Chu Han , Jiatai Lin , Jinhai Mai , Yi Wang , Qingling Zhang , Bingchao Zhao , Xin Chen , Xipeng Pan , Zhenwei Shi , Xiaowei Xu , Su Yao , Lixu Yan , Huan Lin , Zeyan Xu , Xiaomei Huang , Guoqiang Han , Changhong Liang , Zaiyi Liu

Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…

Computer Vision and Pattern Recognition · Computer Science 2016-03-10 Le Hou , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , James E. Davis , Joel H. Saltz

Medical image segmentation can provide a reliable basis for further clinical analysis and disease diagnosis. The performance of medical image segmentation has been significantly advanced with the convolutional neural networks (CNNs).…

Image and Video Processing · Electrical Eng. & Systems 2022-03-02 Ruxin Wang , Shuyuan Chen , Chaojie Ji , Jianping Fan , Ye Li

Pulmonary pathologies are a significant global health concern, often leading to fatal outcomes if not diagnosed and treated promptly. Chest radiography serves as a primary diagnostic tool, but the availability of experienced radiologists…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Abdelbaki Souid , Mohamed Hamroun , Soufiene Ben Othman , Hedi Sakli , Naceur Abdelkarim

Active nematics is an emerging paradigm for characterising biological systems. One aspect of particularly intense focus is the role active nematic defects play in these systems, as they have been found to mediate a growing number of…

Soft Condensed Matter · Physics 2024-01-25 Andrew Killeen , Thibault Bertrand , Chiu Fan Lee

Automatic lesion analysis is critical in skin cancer diagnosis and ensures effective treatment. The computer aided diagnosis of such skin cancer in dermoscopic images can significantly reduce the clinicians workload and help improve…

Image and Video Processing · Electrical Eng. & Systems 2023-01-18 Shubham Innani , Prasad Dutande , Bhakti Baheti , Ujjwal Baid , Sanjay Talbar

Due to the wide existence and large morphological variances of nuclei, accurate nuclei instance segmentation is still one of the most challenging tasks in computational pathology. The annotating of nuclei instances, requiring experienced…

Computer Vision and Pattern Recognition · Computer Science 2020-07-23 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Tumor lesion segmentation on CT or MRI images plays a critical role in cancer diagnosis and treatment planning. Considering the inherent differences in tumor lesion segmentation data across various medical imaging modalities and equipment,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Hairong Shi , Songhao Han , Shaofei Huang , Yue Liao , Guanbin Li , Xiangxing Kong , Hua Zhu , Xiaomu Wang , Si Liu
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