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In human neuroimaging studies, atlas registration enables mapping MRI scans to a common coordinate frame, which is necessary to aggregate data from multiple subjects. Machine learning registration methods have achieved excellent speed and…
Typically, a medical image offers spatial information on the anatomy (and pathology) modulated by imaging specific characteristics. Many imaging modalities including Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) can be…
Atlas building and image registration are important tasks for medical image analysis. Once one or multiple atlases from an image population have been constructed, commonly (1) images are warped into an atlas space to study intra-subject or…
Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…
Motion artifacts caused by prolonged acquisition time are a significant challenge in Magnetic Resonance Imaging (MRI), hindering accurate tissue segmentation. These artifacts appear as blurred images that mimic tissue-like appearances,…
Reconstructing 3D human heads in low-view settings presents technical challenges, mainly due to the pronounced risk of overfitting with limited views and high-frequency signals. To address this, we propose geometry decomposition and adopt a…
Spine image segmentation is crucial for clinical diagnosis and treatment of spine diseases. The complex structure of the spine and the high morphological similarity between individual vertebrae and adjacent intervertebral discs make…
Medical image registration is a fundamental task in medical image analysis, aiming to establish spatial correspondences between paired images. However, existing unsupervised deformable registration methods rely solely on intensity-based…
In medical imaging, most of the image registration methods implicitly assume a one-to-one correspondence between the source and target images (i.e., diffeomorphism). However, this is not necessarily the case when dealing with pathological…
Harnessing the power of pre-training on large-scale datasets like ImageNet forms a fundamental building block for the progress of representation learning-driven solutions in computer vision. Medical images are inherently different from…
The recent application of deep learning in various areas of medical image analysis has brought excellent performance gains. In particular, technologies based on deep learning in medical image registration can outperform traditional…
Probabilistic atlas priors have been commonly used to derive adaptive and robust brain MRI segmentation algorithms. Widely-used neuroimage analysis pipelines rely heavily on these techniques, which are often computationally expensive. In…
Deformable image registration plays a critical role in various tasks of medical image analysis. A successful registration algorithm, either derived from conventional energy optimization or deep networks requires tremendous efforts from…
In brain tumor diagnosis and surgical planning, segmentation of tumor regions and accurate analysis of surrounding normal tissues are necessary for physicians. Pathological variability often renders difficulty to register a well-labeled…
Deformable registration of magnetic resonance images between patients with brain tumors and healthy subjects has been an important tool to specify tumor geometry through location alignment and facilitate pathological analysis. Since tumor…
We describe an adversarial learning approach to constrain convolutional neural network training for image registration, replacing heuristic smoothness measures of displacement fields often used in these tasks. Using minimally-invasive…
Image registration and in particular deformable registration methods are pillars of medical imaging. Inspired by the recent advances in deep learning, we propose in this paper, a novel convolutional neural network architecture that couples…
Image registration techniques usually assume that the images to be registered are of a certain type (e.g. single- vs. multi-modal, 2D vs. 3D, rigid vs. deformable) and there lacks a general method that can work for data under all…
We propose a novel machine learning strategy for studying neuroanatomical shape variation. Our model works with volumetric binary segmentation images, and requires no pre-processing such as the extraction of surface points or a mesh. The…
Medical image analysis tasks often focus on regions or structures located in a particular location within the patient's body. Often large parts of the image may not be of interest for the image analysis task. When using deep-learning based…