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Although Raman spectroscopy is widely used for the investigation of biomedical samples and has a high potential for use in clinical applications, it is not common in clinical routines. One of the factors that obstruct the integration of…

Data Analysis, Statistics and Probability · Physics 2022-01-20 Darina Storozhuk , Oleg Ryabchykov , Juergen Popp , Thomas Bocklitz

PySDM is an open-source Python package for simulating the dynamics of particles undergoing condensational and collisional growth, interacting with a fluid flow and subject to chemical composition changes. It is intended to serve as a…

MRI and PET are important modalities and can provide complementary information for the diagnosis of brain diseases because MRI can provide structural information of brain and PET can obtain functional information of brain. However, PET is…

Multimedia · Computer Science 2023-04-18 Taofeng Xie , Chentao Cao , Zhuoxu Cui , Fanshi Li , Zidong Wei , Yanjie Zhu , Ye Li , Dong Liang , Qiyu Jin , Guoqing Chen , Haifeng Wang

Synthetic tumors in medical images offer controllable characteristics that facilitate the training of machine learning models, leading to an improved segmentation performance. However, the existing methods of tumor synthesis yield…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Hongxu Yang , Edina Timko , Levente Lippenszky , Vanda Czipczer , Lehel Ferenczi

In recent advancements in proton therapy, MR-based treatment planning is gaining momentum to minimize additional radiation exposure compared to traditional CT-based methods. This transition highlights the critical need for accurate MR-to-CT…

Medical Physics · Physics 2024-07-02 Muheng Li , Xia Li , Sairos Safai , Damien Weber , Antony Lomax , Ye Zhang

Active inference is an account of cognition and behavior in complex systems which brings together action, perception, and learning under the theoretical mantle of Bayesian inference. Active inference has seen growing applications in…

Artificial Intelligence · Computer Science 2022-05-06 Conor Heins , Beren Millidge , Daphne Demekas , Brennan Klein , Karl Friston , Iain Couzin , Alexander Tschantz

Positron emission tomography (PET) is a well-established functional imaging technique for diagnosing brain disorders. However, PET's high costs and radiation exposure limit its widespread use. In contrast, magnetic resonance imaging (MRI)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Yitong Li , Igor Yakushev , Dennis M. Hedderich , Christian Wachinger

High-fidelity computational fluid dynamics (CFD) is widely used for thermal-fluid design, but repeated CFD solves remain expensive for design optimization, uncertainty analysis, and digital-twin workflows. Recently, our team has…

Fluid Dynamics · Physics 2026-05-28 Daniel Curl , Han Hu

Heart murmurs are abnormal sounds caused by turbulent blood flow in the heart. Several diagnostic methods are available to detect heart murmurs and their severity, including cardiac auscultation, echocardiography, and phonocardiography…

Signal Processing · Electrical Eng. & Systems 2026-05-12 Md Jobayer , Md. Mehedi Hasan Shawon , Md Zakir Hossain , Shreya Ghosh , Imre Rudas , Tom Gedeon , Md Rakibul Hasan

PaPy, which stands for parallel pipelines in Python, is a highly flexible framework that enables the construction of robust, scalable workflows for either generating or processing voluminous datasets. A workflow is created from user-written…

Programming Languages · Computer Science 2014-07-17 Marcin Cieslik , Cameron Mura

PyMembrane is a software package for simulating liquid and elastic membranes using a discretisation of the continuum description based on unstructured triangulated two-dimensional meshes embedded in three-dimensional space. The package is…

Soft Condensed Matter · Physics 2023-08-25 D. A. Matoz-Fernandez , Siyu Li , Monica Olvera de la Cruz , Rastko Sknepnek

Continuous Wavelet Transform (CWT) is frequently used for waveform analysis. For example, in the field of neuroscience research, CWT is performed to analyze electroencephalograms (EEG) and calculate the index of brain activity. Recent…

Quantitative Methods · Quantitative Biology 2025-06-10 Shoichiro Nakanishi

Particle therapy is an established method to treat deep-seated tumours using accelerator-produced ion beams. For treatment planning, the precise knowledge of the relative stopping power (RSP) within the patient is vital. Conversion errors…

We present PepTune, a multi-objective discrete diffusion model for simultaneous generation and optimization of therapeutic peptide SMILES. Built on the Masked Discrete Language Model (MDLM) framework, PepTune ensures valid peptide…

Biomolecules · Quantitative Biology 2025-06-03 Sophia Tang , Yinuo Zhang , Pranam Chatterjee

The PySCF package has emerged as a powerful and flexible open-source platform for quantum chemistry simulations. However, the efficiency of electronic structure calculations can vary significantly depending on the choice of computational…

Chemical Physics · Physics 2025-06-10 Zhichen Pu , Qiming Sun

Time is a fundamental factor during stroke treatments. A fast, automatic approach that segments the ischemic regions helps treatment decisions. In clinical use today, a set of color-coded parametric maps generated from computed tomography…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Luca Tomasetti , Mahdieh Khanmohammadi , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz

Medical education relies heavily on Simulated Patients (SPs) to provide a safe environment for students to practice clinical skills, including medical image analysis. However, the high cost of recruiting qualified SPs and the lack of…

Artificial Intelligence · Computer Science 2024-08-23 Yanzeng Li , Cheng Zeng , Jinchao Zhang , Jie Zhou , Lei Zou

Low-dose Proton Computed Tomography (pCT) is an evolving imaging modality that is used in proton therapy planning which addresses the range uncertainty problem. The goal of pCT is generating a 3D map of Relative Stopping Power (RSP)…

Single-photon emission computed tomography for myocardial perfusion imaging (MPI SPECT) is a widely used diagnostic tool for coronary artery disease. However, the procedure requires considerable scanning time, leading to patient discomfort…

Image and Video Processing · Electrical Eng. & Systems 2026-04-27 Zezhang Yang , Zitong Yu , Nuri Choi , Janice Tania , Wenxuan Xue , Barry A. Siegel , Abhinav K. Jha

Open-source process mining provides many algorithms for the analysis of event data which could be used to analyze mainstream processes (e.g., O2C, P2P, CRM). However, compared to commercial tools, they lack the performance and struggle to…

Databases · Computer Science 2022-04-12 Alessandro Berti , Minh Phan Nghia , Wil M. P. van der Aalst
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