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Related papers: Bridging the genotype-phenotype gap with generativ…

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Genotype-phenotype (GP) maps specify how the random mutations that change genotypes generate variation by altering phenotypes, which, in turn, can trigger selection. Many GP maps share the following general properties: 1) The number of…

Populations and Evolution · Quantitative Biology 2014-02-07 Ard A Louis , Steffen Schaper

Genetic association studies for brain connectivity phenotypes have gained prominence due to advances in non-invasive imaging techniques and quantitative genetics. Brain connectivity traits, characterized by network configurations and unique…

Methodology · Statistics 2023-05-17 Xinyuan Tian , Yiting Wang , Selena Wang , Yi Zhao , Yize Zhao

Generative AI systems have entered everyday academic, professional, and personal life with remarkable speed, yet most users encounter them as mysterious artifacts rather than intelligible systems. This chapter discusses large language…

Computers and Society · Computer Science 2026-04-21 John T. Behrens

Generative Artificial Intelligence (GAI) represents an emerging field that promises the creation of synthetic data and outputs in different modalities. GAI has recently shown impressive results across a large spectrum of applications…

Geophysics · Physics 2025-02-18 Abdenour Hadid , Tanujit Chakraborty , Daniel Busby

Many genetic mutations adversely affect the structure and function of load-bearing soft tissues, with clinical sequelae often responsible for disability or death. Parallel advances in genetics and histomechanical characterization provide…

Tissues and Organs · Quantitative Biology 2023-01-11 Enrui Zhang , Bart Spronck , Jay D. Humphrey , George Em Karniadakis

Background: The learning of genotype-phenotype associations and history of human disease by doing detailed and precise analysis of phenotypic abnormalities can be defined as deep phenotyping. To understand and detect this interaction…

Artificial Intelligence · Computer Science 2021-06-04 Rushabh Patel , Yanhui Guo

Emerging research has highlighted that artificial intelligence-based multimodal fusion of digital pathology and transcriptomic features can improve cancer diagnosis (grading/subtyping) and prognosis (survival risk) prediction. However, such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Samiran Dey , Christopher R. S. Banerji , Partha Basuchowdhuri , Sanjoy K. Saha , Deepak Parashar , Tapabrata Chakraborti

With recent progress in deep generative models, the problem of identifying synthetic data and comparing their underlying generative processes has become an imperative task for various reasons, including fighting visual misinformation and…

Machine Learning · Computer Science 2022-06-07 Hae Jin Song , Wael AbdAlmageed

Recent advances in generative AI have brought incredible breakthroughs in several areas, including medical imaging. These generative models have tremendous potential not only to help safely share medical data via synthetic datasets but also…

Recently, the quality of artworks generated using Artificial Intelligence (AI) has increased significantly, resulting in growing difficulties in detecting synthetic artworks. However, limited studies have been conducted on identifying the…

Artificial Intelligence · Computer Science 2024-12-03 Ravidu Suien Rammuni Silva , Ahmad Lotfi , Isibor Kennedy Ihianle , Golnaz Shahtahmassebi , Jordan J. Bird

In this research work we have proposed high-level ChildDiffusion framework capable of generating photorealistic child facial samples and further embedding several intelligent augmentations on child facial data using short text prompts,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-23 Muhammad Ali Farooq , Wang Yao , Peter Corcoran

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

AI systems rely on extensive training on large datasets to address various tasks. However, image-based systems, particularly those used for demographic attribute prediction, face significant challenges. Many current face image datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Georgia Baltsou , Ioannis Sarridis , Christos Koutlis , Symeon Papadopoulos

Photorealistic image generation has reached a new level of quality due to the breakthroughs of generative adversarial networks (GANs). Yet, the dark side of such deepfakes, the malicious use of generated media, raises concerns about visual…

Cryptography and Security · Computer Science 2022-03-21 Ning Yu , Vladislav Skripniuk , Sahar Abdelnabi , Mario Fritz

Generative artificial intelligence (AI) technology is revolutionizing the computing industry. Not only its applications have broadened to various sectors but also poses new system design and optimization opportunities. The technology is…

Genetic variants (GVs) are defined as differences in the DNA sequences among individuals and play a crucial role in diagnosing and treating genetic diseases. The rapid decrease in next generation sequencing cost has led to an exponential…

Machine Learning · Computer Science 2024-12-06 Zehui Li , Vallijah Subasri , Guy-Bart Stan , Yiren Zhao , Bo Wang

Many important decisions in our everyday lives, such as authentication via biometric models, are made by Artificial Intelligence (AI) systems. These can be in poor alignment with human expectations, and testing them on clear-cut existing…

Human-Computer Interaction · Computer Science 2024-09-20 Lukas Mecke , Daniel Buschek , Uwe Gruenefeld , Florian Alt

This paper introduces a simple JavaScript-based web application designed to assist educators in detecting AI-generated content in student essays and written assignments. Unlike existing AI detection tools that rely on obfuscated machine…

Human-Computer Interaction · Computer Science 2025-03-24 Andy Buschmann

Early and accurate disease detection is crucial for patient management and successful treatment outcomes. However, the automatic identification of anomalies in medical images can be challenging. Conventional methods rely on large labeled…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Cosmin I Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A Schnabel

Despite recent successes in hair acquisition that fits a high-dimensional hair model to a specific input subject, generative hair models, which establish general embedding spaces for encoding, editing, and sampling diverse hairstyles, are…

Graphics · Computer Science 2023-11-20 Yuxiao Zhou , Menglei Chai , Alessandro Pepe , Markus Gross , Thabo Beeler