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Related papers: Bridging the genotype-phenotype gap with generativ…

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The advance of Generative Adversarial Networks (GANs) enables realistic face image synthesis. However, synthesizing face images that preserve facial identity as well as have high diversity within each identity remains challenging. To…

Computer Vision and Pattern Recognition · Computer Science 2018-12-05 Yujun Shen , Bolei Zhou , Ping Luo , Xiaoou Tang

Generative methods (Gen-AI) are reviewed with a particular goal of solving tasks in machine learning and Bayesian inference. Generative models require one to simulate a large training dataset and to use deep neural networks to solve a…

Computation · Statistics 2025-05-20 Maria Nareklishvili , Nick Polson , Vadim Sokolov

Accurate phenotypic analysis in aquaculture breeding necessitates the quantification of subtle morphological phenotypes. Existing datasets suffer from limitations such as small scale, limited species coverage, and inadequate annotation of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Weizhen Liu , Jiayu Tan , Guangyu Lan , Ao Li , Dongye Li , Le Zhao , Xiaohui Yuan , Nanqing Dong

Recently, it has become progressively more evident that classic diagnostic labels are unable to reliably describe the complexity and variability of several clinical phenotypes. This is particularly true for a broad range of neuropsychiatric…

Machine Learning · Computer Science 2024-02-28 Giovanna Maria Dimitri , Simeon Spasov , Andrea Duggento , Luca Passamonti , Pietro Li`o , Nicola Toschi

Recent image generation models have shown strong capabilities in generating high-fidelity and photorealistic images. However, they are fundamentally constrained by frozen internal knowledge, thus often failing on real-world scenarios that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Kaituo Feng , Manyuan Zhang , Shuang Chen , Yunlong Lin , Kaixuan Fan , Yilei Jiang , Hongyu Li , Dian Zheng , Chenyang Wang , Xiangyu Yue

In this work, we propose a new deep learning model for Genomic Prediction (GP), which involves correlating genotypic data with phenotypic. The genotypes are typically fed as a sequence of characters to the 1D-Convolution Neural Network…

Machine Learning · Computer Science 2026-03-03 Kuldeep Pathak , Kapil Ahuja , Eric de Sturler

Data-driven medical AI is traditionally formulated as a discriminative mapping from input $X$ to output $Y$ via a learned function $f$, which does not generalize well across heterogeneous data and modalities encountered in real-world…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Hantao Zhang , Weidong Guo , Yuhe Liu , Jiancheng Yang , Sathvik Bhagavan , Danli Shi , Mingda Xu , Pascal Fua

The rise of generative AI (GenAI) chatbots accessible via conversational interfaces is transforming digital interactions and holds economic promise. However, these tools might deepen existing inequalities -- not only through uneven,…

Simulating in silico cellular responses to interventions is a promising direction to accelerate high-content image-based assays, critical for advancing drug discovery and gene editing. To support this, we introduce MorphGen, a…

Quantitative Methods · Quantitative Biology 2025-10-13 Berker Demirel , Marco Fumero , Theofanis Karaletsos , Francesco Locatello

Genotype-to-phenotype prediction is a central goal of statistical genetics, yet practical comparisons of prediction workflows remain limited in small, heterogeneous, participant-shared genomic datasets. Here, we benchmarked end-to-end…

Genomics · Quantitative Biology 2026-05-05 Muhammad Muneeb , David B. Ascher , YooChan Myung , Samuel F. Feng , Andreas Henschel

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

For the past few years, deep generative models have increasingly been used in biological research for a variety of tasks. Recently, they have proven to be valuable for uncovering subtle cell phenotypic differences that are not directly…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Anis Bourou , Thomas Boyer , Kévin Daupin , Véronique Dubreuil , Aurélie De Thonel , Valérie Mezger , Auguste Genovesio

The massive and large-scale design of foundational semiconductor integrated circuits (ICs) is crucial to sustaining the advancement of many emerging and future technologies, such as generative AI, 5G/6G, and quantum computing. Excitingly,…

Machine Learning · Computer Science 2025-03-04 Jian Gao , Weidong Cao , Junyi Yang , Xuan Zhang

Bayesian Generative AI (BayesGen-AI) methods are developed and applied to Bayesian computation. BayesGen-AI reconstructs the posterior distribution by directly modeling the parameter of interest as a mapping (a.k.a. deep learner) from a…

Computation · Statistics 2024-02-27 Nicholas G. Polson , Vadim Sokolov

Generative AI is transforming image synthesis, enabling the creation of high-quality, diverse, and photorealistic visuals across industries like design, media, healthcare, and autonomous systems. Advances in techniques such as…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Fouad Bousetouane

Generative AI (GenAI) is transforming filmmaking, equipping artists with tools like text-to-image and image-to-video diffusion, neural radiance fields, avatar generation, and 3D synthesis. This paper examines the adoption of these…

Design inspiration is crucial for establishing the direction of a design as well as evoking feelings and conveying meanings during the conceptual design process. Many practice designers use text-based searches on platforms like Pinterest to…

Human-Computer Interaction · Computer Science 2024-07-18 Ye Wang , Nicole B. Damen , Thomas Gale , Voho Seo , Hooman Shayani

The rapid advancement of AI generated content (AIGC) has blurred the boundaries between real and synthetic images, exposing the limitations of existing deepfake detectors that often overfit to specific generative models. This adaptability…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Mei Qiu , Jianqiang Zhao , Yanyun Qu

Generative Artificial Intelligence (GenAI) is a field of AI that creates new data samples from existing ones. It utilizing deep learning to overcome the scarcity and regulatory constraints of healthcare data by generating new data points…

Machine Learning · Computer Science 2024-10-02 Sarthak Pati , Szymon Mazurek , Spyridon Bakas

Polygenic risk scores and other genomic analyses require large individual-level genotype datasets, yet strict data access restrictions impede sharing. Synthetic genotype generation offers a privacy-preserving alternative, but most existing…