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Anomaly detection in MRI is of high clinical value in imaging and diagnosis. Unsupervised methods for anomaly detection provide interesting formulations based on reconstruction or latent embedding, offering a way to observe properties…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Ayantika Das , Arun Palla , Keerthi Ram , Mohanasankar Sivaprakasam

Unsupervised anomaly detection (UAD) in brain imaging is crucial for identifying pathologies without the need for labeled data. However, accurately localizing anomalies remains challenging due to the intricate structure of brain anatomy and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Farzad Beizaee , Sina Hajimiri , Ismail Ben Ayed , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Reconstruction-based anomaly detection models achieve their purpose by suppressing the generalization ability for anomaly. However, diverse normal patterns are consequently not well reconstructed as well. Although some efforts have been…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Wenrui Liu , Hong Chang , Bingpeng Ma , Shiguang Shan , Xilin Chen

Unsupervised anomaly detection (UAD) aims to find anomalous images by optimising a detector using a training set that contains only normal images. UAD approaches can be based on reconstruction methods, self-supervised approaches, and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Yu Tian , Guansong Pang , Yuyuan Liu , Chong Wang , Yuanhong Chen , Fengbei Liu , Rajvinder Singh , Johan W Verjans , Mengyu Wang , Gustavo Carneiro

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Unsupervised Continuous Anomaly Detection (UCAD) is gaining attention for effectively addressing the catastrophic forgetting and heavy computational burden issues in traditional Unsupervised Anomaly Detection (UAD). However, existing UCAD…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Mingle Zhou , Jiahui Liu , Jin Wan , Gang Li , Min Li

Unsupervised anomaly detection (UAD) is a key ingredient of automated visual inspection in modern manufacturing. The reconstruction-based methods appeal because they have basic architectural design and they process data quickly but they…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Dmytro Filatov , Valentyn Fedorov , Vira Filatova , Andrii Zelenchuk

Reliable anomaly detection in brain MRI remains challenging due to the scarcity of annotated abnormal cases and the frequent absence of key imaging modalities in real clinical workflows. Existing single-class or multi-class anomaly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Changwei Wu , Yifei Chen , Yuxin Du , Mingxuan Liu , Jinying Zong , Beining Wu , Jie Dong , Feiwei Qin , Yunkang Cao , Qiyuan Tian

The detection of lesions in magnetic resonance imaging (MRI)-scans of human brains remains challenging, time-consuming and error-prone. Recently, unsupervised anomaly detection (UAD) methods have shown promising results for this task. These…

Image and Video Processing · Electrical Eng. & Systems 2022-04-13 Finn Behrendt , Marcel Bengs , Frederik Rogge , Julia Krüger , Roland Opfer , Alexander Schlaefer

Time series anomaly detection is a challenging problem due to the complex temporal dependencies and the limited label data. Although some algorithms including both traditional and deep models have been proposed, most of them mainly focus on…

Machine Learning · Computer Science 2023-03-28 Chaoli Zhang , Tian Zhou , Qingsong Wen , Liang Sun

Fully Unsupervised Anomaly Detection (FUAD) is a practical extension of Unsupervised Anomaly Detection (UAD), aiming to detect anomalies without any labels even when the training set may contain anomalous samples. To achieve FUAD, we…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Xinyue Liu , Jianyuan Wang , Biao Leng , Shuo Zhang

Unsupervised anomaly detection (UAD) aims to identify image- and pixel-level anomalies using only normal training data, with wide applications such as industrial inspection and medical analysis, where anomalies are scarce due to privacy…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Zhe Zhang , Mingxiu Cai , Gaochang Wu , Jing Zhang , Lingqiao Liu , Dacheng Tao , Tianyou Chai , Xiatian Zhu

Contrastive Analysis (CA) detects anomalies by contrasting patterns unique to a target group (e.g., unhealthy subjects) from those in a background group (e.g., healthy subjects). In the context of brain MRIs, existing CA approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Cristiano Patrício , Carlo Alberto Barbano , Attilio Fiandrotti , Riccardo Renzulli , Marco Grangetto , Luis F. Teixeira , João C. Neves

Unsupervised anomaly detection has gained significant attention in the field of medical imaging due to its capability of relieving the costly pixel-level annotation. To achieve this, modern approaches usually utilize generative models to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Rui Xu , Yunke Wang , Bo Du

Deep unsupervised approaches are gathering increased attention for applications such as pathology detection and segmentation in medical images since they promise to alleviate the need for large labeled datasets and are more generalizable…

Computer Vision and Pattern Recognition · Computer Science 2023-08-01 Ioannis Lagogiannis , Felix Meissen , Georgios Kaissis , Daniel Rueckert

Brain pathologies can vary greatly in size and shape, ranging from few pixels (i.e. MS lesions) to large, space-occupying tumors. Recently proposed Autoencoder-based methods for unsupervised anomaly segmentation in brain MRI have shown…

Image and Video Processing · Electrical Eng. & Systems 2020-06-24 Christoph Baur , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Expert interpretation of anatomical images of the human brain is the central part of neuro-radiology. Several machine learning-based techniques have been proposed to assist in the analysis process. However, the ML models typically need to…

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Resting-state fMRI has become a valuable tool for classifying brain disorders and constructing brain functional connectivity networks by tracking BOLD signals across brain regions. However, existing mod els largely neglect the…

Machine Learning · Computer Science 2025-11-18 Yue Xun , Jiaxing Xu , Wenbo Gao , Chen Yang , Shujun Wang