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In solving real-world problems like changing healthcare-seeking behaviors, designing interventions to improve downstream outcomes requires an understanding of the causal links within the system. Causal Bayesian Networks (BN) have been…

Artificial Intelligence · Computer Science 2022-02-18 Bradley Butcher , Vincent S. Huang , Jeremy Reffin , Sema K. Sgaier , Grace Charles , Novi Quadrianto

In many biological systems, the network of interactions between the elements can only be inferred from experimental measurements. In neuroscience, non-invasive imaging tools are extensively used to derive either structural or functional…

Neurons and Cognition · Quantitative Biology 2017-02-14 Fabrizio De Vico Fallani , Vito Latora , Mario Chavez

We consider the problem of estimating the causal effect of a treatment on an outcome in linear structural causal models (SCM) with latent confounders when we have access to a single proxy variable. Several methods (such as…

Computational Engineering, Finance, and Science · Computer Science 2023-06-13 Yaroslav Kivva , Saber Salehkaleybar , Negar Kiyavash

There is an ongoing and dedicated effort to estimate bounds on the generalization error of deep learning models, coupled with an increasing interest with practical metrics that can be used to experimentally evaluate a model's ability to…

Machine Learning · Computer Science 2024-09-04 Mengqing Huang , Hongchuan Yu , Jianjun Zhang

Data selection seeks to identify a compact yet informative subset from large-scale training corpora, balancing sample quality against collection diversity. We formulate this problem as a Weighted Independent Set (WIS) on a similarity graph,…

Machine Learning · Computer Science 2026-05-21 Yuan Zhang , Lifeng Guo , Junwen Pan , Wenzhao Zheng , Wen Zhou , Kuan Cheng , Kurt Keutzer , Shanghang Zhang

Autism spectrum disorder (ASD) is a neurodevelopmental condition impacting high-level cognitive processing and social behavior. Recognizing the distributed nature of brain function, neuroscientists are exploiting the connectome to aid with…

Neurons and Cognition · Quantitative Biology 2019-09-26 Ai Wern Chung , Markus D. Schirmer

We propose a generalization of the synthetic controls and synthetic interventions methodology to incorporate network interference. We consider the estimation of unit-specific potential outcomes from panel data in the presence of spillover…

Econometrics · Economics 2023-10-13 Anish Agarwal , Sarah H. Cen , Devavrat Shah , Christina Lee Yu

Stepped wedge designs (SWDs) are increasingly used to evaluate longitudinal cluster-level interventions but pose substantial challenges for valid inference. Because crossover times are randomized, intervention effects are intrinsically…

Methodology · Statistics 2026-05-12 Fan Xia , K. C. Gary Chan , Emily Voldal , Avi Kenny , Patrick J. Heagerty , James P. Hughes

Causal effect estimation in networked systems is central to data-driven decision making. In such settings, interventions on one unit can spill over to others, and in complex physical or social systems, the interaction pathways driving these…

Machine Learning · Statistics 2025-11-27 Sadegh Shirani , Mohsen Bayati

Over the past decade, neural networks have been successful at making predictions from biological sequences, especially in the context of regulatory genomics. As in other fields of deep learning, tools have been devised to extract features…

Genomics · Quantitative Biology 2022-12-27 Antoine Villié , Philippe Veber , Yohann de Castro , Laurent Jacob

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

Dynamic networks models describe a growing number of important scientific processes, from cell biology and epidemiology to sociology and finance. There are many aspects of dynamical networks that require statistical considerations. In this…

Methodology · Statistics 2012-05-15 E. C. Wit , A. Abbruzzo

Network intrusion detection systems (NIDSs) have a role of identifying malicious activities by monitoring the behavior of networks. Due to the currently high volume of networks trafic in addition to the increased number of attacks and their…

Neural and Evolutionary Computing · Computer Science 2014-05-07 Omar S. Soliman , Aliaa Rassem

Inferring causation from time series data is of scientific interest in different disciplines, particularly in neural connectomics. While different approaches exist in the literature with parametric modeling assumptions, we focus on a…

Methodology · Statistics 2023-12-18 Rahul Biswas , SuryaNarayana Sripada , Somabha Mukherjee

Bayesian networks are one of the most widely used classes of probabilistic models for risk management and decision support because of their interpretability and flexibility in including heterogeneous pieces of information. In any applied…

Methodology · Statistics 2024-07-08 Manuele Leonelli , Jim Q. Smith , Sophia K. Wright

Causal learning from data has received much attention recently. Bayesian networks can be used to capture causal relationships. There, one recovers a weighted directed acyclic graph in which random variables are represented by vertices, and…

Machine Learning · Computer Science 2026-01-06 Pavel Rytir , Ales Wodecki , Georgios Korpas , Jakub Marecek

While much of the causal inference literature has focused on addressing internal validity biases, both internal and external validity are necessary for unbiased estimates in a target population of interest. However, few generalizability…

Methodology · Statistics 2023-04-07 Irina Degtiar , Tim Layton , Jacob Wallace , Sherri Rose

Causal Bayesian networks are 'causal' models since they make predictions about interventional distributions. To connect such causal model predictions to real-world outcomes, we must determine which actions in the world correspond to which…

Machine Learning · Statistics 2025-02-04 Frederik Hytting Jørgensen , Luigi Gresele , Sebastian Weichwald

Identifying network structure and inferring parameters are central challenges in modeling chemical reaction networks. In this study, we propose likelihood-based methods grounded in multinomial logistic regression to infer both…

Quantitative Methods · Quantitative Biology 2025-07-29 Boseung Choi , Hey-Won Kang , Grzegorz A. Rempala

We develop the theory and practice of an approach to modelling and probabilistic inference in causal networks that is suitable when application-specific or analysis-specific constraints should inform such inference or when little or no data…

Artificial Intelligence · Computer Science 2017-05-16 Paul Beaumont , Michael Huth