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Related papers: MolEdit: Knowledge Editing for Multimodal Molecule…

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Large Language Models (LLMs) have shown extraordinary capabilities in understanding and generating text that closely mirrors human communication. However, a primary limitation lies in the significant computational demands during training,…

Large language models (LLMs) are deployed on mobile devices to power killer applications such as intelligent assistants. LLMs pre-trained on general corpora often hallucinate when handling personalized or unseen queries, leading to…

Machine Learning · Computer Science 2025-06-18 Zhenyan Lu , Daliang Xu , Dongqi Cai , Zexi Li , Wei Liu , Fangming Liu , Shangguang Wang , Mengwei Xu

In this paper, we focus on editing Multimodal Large Language Models (MLLMs). Compared to editing single-modal LLMs, multimodal model editing is more challenging, which demands a higher level of scrutiny and careful consideration in the…

Computation and Language · Computer Science 2024-04-19 Siyuan Cheng , Bozhong Tian , Qingbin Liu , Xi Chen , Yongheng Wang , Huajun Chen , Ningyu Zhang

Model editing aims to correct inaccurate knowledge, update outdated information, and incorporate new data into Large Language Models (LLMs) without the need for retraining. This task poses challenges in lifelong scenarios where edits must…

Computation and Language · Computer Science 2025-03-17 Qizhou Chen , Chengyu Wang , Dakan Wang , Taolin Zhang , Wangyue Li , Xiaofeng He

Molecular knowledge resides within three different modalities of information sources: molecular structures, biomedical documents, and knowledge bases. Effective incorporation of molecular knowledge from these modalities holds paramount…

Biomolecules · Quantitative Biology 2023-07-24 Yizhen Luo , Kai Yang , Massimo Hong , Xing Yi Liu , Zaiqing Nie

Large Language Models (LLMs) with their strong task-handling capabilities have shown remarkable advancements across a spectrum of fields, moving beyond natural language understanding. However, their proficiency within the chemistry domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Khiem Le , Zhichun Guo , Kaiwen Dong , Xiaobao Huang , Bozhao Nan , Roshni Iyer , Xiangliang Zhang , Olaf Wiest , Wei Wang , Ting Hua , Nitesh V. Chawla

Multimodal large language models (MLLMs) are prone to non-factual or outdated knowledge issues, which can manifest as misreading and misrecognition errors due to the complexity of multimodal knowledge. Previous benchmarks have not…

Computer Vision and Pattern Recognition · Computer Science 2024-10-31 Junzhe Zhang , Huixuan Zhang , Xunjian Yin , Baizhou Huang , Xu Zhang , Xinyu Hu , Xiaojun Wan

Molecular editing and optimization are multi-step problems that require iteratively improving properties while keeping molecules chemically valid and structurally similar. We frame both tasks as sequential, tool-guided decisions and…

Artificial Intelligence · Computer Science 2025-12-25 Zhuo Yang , Yeyun Chen , Jiaqing Xie , Ben Gao , Shuaike Shen , Wanhao Liu , Liujia Yang , Beilun Wang , Tianfan Fu , Yuqiang Li

Molecular editing aims to modify a given molecule to optimize desired chemical properties while preserving structural similarity. However, current approaches typically rely on string-based or continuous representations, which fail to…

Machine Learning · Computer Science 2025-05-27 Yuanxin Zhuang , Dazhong Shen , Ying Sun

Knowledge editing enables multimodal large language models (MLLMs) to efficiently update outdated or incorrect information. However, existing benchmarks primarily emphasize cognitive-level modifications while lacking a focus on deeper…

Artificial Intelligence · Computer Science 2025-09-09 Zhaoyu Fan , Kaihang Pan , Mingze Zhou , Bosheng Qin , Juncheng Li , Shengyu Zhang , Wenqiao Zhang , Siliang Tang , Fei Wu , Yueting Zhuang

Large Language Models (LLMs) usually suffer from knowledge cutoff or fallacy issues, which means they are unaware of unseen events or generate text with incorrect facts owing to outdated/noisy data. To this end, many knowledge editing…

Model editing aims to efficiently update a pre-trained model's knowledge without the need for time-consuming full retraining. While existing pioneering editing methods achieve promising results, they primarily focus on editing single-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Zhiyi Shi , Binjie Wang , Chongjie Si , Yichen Wu , Junsik Kim , Hanspeter Pfister

Recent advances in multimodal large language models (MLLMs) have significantly improved medical AI, enabling it to unify the understanding of visual and textual information. However, as medical knowledge continues to evolve, it is critical…

Artificial Intelligence · Computer Science 2025-08-08 Dexuan Xu , Jieyi Wang , Zhongyan Chai , Yongzhi Cao , Hanpin Wang , Huamin Zhang , Yu Huang

Large multimodal language models (MLLMs) have revolutionized natural language processing and visual understanding, but often contain outdated or inaccurate information. Current multimodal knowledge editing evaluations are limited in scope…

Computer Vision and Pattern Recognition · Computer Science 2024-12-18 Yaohui Ma , Xiaopeng Hong , Shizhou Zhang , Huiyun Li , Zhilin Zhu , Wei Luo , Zhiheng Ma

Knowledge editing for large language models can offer an efficient solution to alter a model's behavior without negatively impacting the overall performance. However, the current approaches encounter issues with limited generalizability…

Computation and Language · Computer Science 2024-04-30 Ningyu Zhang , Bozhong Tian , Siyuan Cheng , Xiaozhuan Liang , Yi Hu , Kouying Xue , Yanjie Gou , Xi Chen , Huajun Chen

Precise recognition, editing, and generation of molecules are essential prerequisites for both chemists and AI systems tackling various chemical tasks. We present MolLangBench, a comprehensive benchmark designed to evaluate fundamental…

Computation and Language · Computer Science 2026-03-24 Feiyang Cai , Jiahui Bai , Tao Tang , Guijuan He , Joshua Luo , Tianyu Zhu , Srikanth Pilla , Gang Li , Ling Liu , Feng Luo

Knowledge editing (KE) enables precise modifications to factual content in large language models (LLMs). Existing KE methods are largely designed for dense architectures, limiting their applicability to the increasingly prevalent sparse…

Machine Learning · Computer Science 2026-02-12 Yupu Gu , Rongzhe Wei , Andy Zhu , Pan Li

Model editing aims to enhance the accuracy and reliability of large language models (LLMs) by efficiently adjusting their internal parameters. Currently, most LLM editing datasets are confined to narrow knowledge domains and cover a limited…

Computation and Language · Computer Science 2025-11-12 Qizhou Chen , Dakan Wang , Taolin Zhang , Zaoming Yan , Chengsong You , Chengyu Wang , Xiaofeng He

Most current molecular language models transfer the masked language model or image-text generation model from natural language processing to molecular field. However, molecules are not solely characterized by atom/bond symbols; they…

Emerging Technologies · Computer Science 2024-11-26 Yifan Wu , Min Zeng , Yang Li , Yang Zhang , Min Li

Model editing aims to correct outdated or erroneous knowledge in large models without costly retraining. Recent research discovered that the mid-layer representation of the subject's final token in a prompt has a strong influence on factual…

Computer Vision and Pattern Recognition · Computer Science 2025-01-24 Qizhou Chen , Taolin Zhang , Chengyu Wang , Xiaofeng He , Dakan Wang , Tingting Liu
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