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Real-world vaccine effectiveness has increasingly been studied using matching-based approaches, particularly in observational cohort studies following the target trial emulation framework. Although matching is appealing in its simplicity,…

Methodology · Statistics 2026-04-07 Emily Wu , Elizabeth Rogawski McQuade , Mats Stensrud , Razieh Nabi , David Benkeser

Measles is a significant source of global disease burden and child mortality. Measles vaccination through routine immunization (RI) programs in high-burden settings remains a challenge due to poor health care infrastructure and access.…

Methodology · Statistics 2020-10-20 Tracy Qi Dong , Jon Wakefield

The mainstay of canine rabies control is fixed point mass dog vaccination campaigns (MDVC). However, in some regions, ideal vaccination coverage in dogs is not obtained due to low participation in the MDVC. Travel distance to the…

Vaccination is widely recognized as the most effective way of immunization against many infectious diseases. However, unfounded claims about supposed side effects of some vaccines have contributed to spread concern and fear among people,…

Physics and Society · Physics 2014-12-03 A. D. Medus , C. O. Dorso

Two observational methods are currently being used to monitor post-deployment vaccine effectiveness: the obvious crude method comparing rate testing positive per head of vaccinated population with that rate per head of unvaccinated…

Methodology · Statistics 2023-07-18 Roger F. Sewell

The pursuit of strategies that minimize the number of individuals needing vaccination to control an outbreak is a well-established area of study in mathematical epidemiology. However, for certain diseases, public policy tends to prioritize…

Populations and Evolution · Quantitative Biology 2026-01-30 J. Orestes Cerdeira , Fabio A. C. C. Chalub , Matheus Hansen

Misclassification in binary outcomes is not uncommon and statistical methods to investigate its impact on policy-driving study results are lacking. While misclassifying binary outcomes is a statistically ubiquitous phenomena, we focus on…

The problem of targeted network immunization can be defined as the one of finding a subset of nodes in a network to immunize or vaccinate in order to minimize a tradeoff between the cost of vaccination and the final (stationary) expected…

Physics and Society · Physics 2015-07-10 F. Altarelli , A. Braunstein , L. Dall'Asta , J. R. Wakeling , R. Zecchina

Optimization of vaccine allocations among different segments of a heterogeneous population is important for enhancing the effectiveness of vaccination campaigns in reducing the burden of epidemics. Intuitively, it would seem that…

Quantitative Methods · Quantitative Biology 2022-12-01 Nir Gavish , Guy Katriel

With significant population fractions in many societies who refuse vaccines, it is important to reconsider how vaccination is incorporated into compartmental epidemiology models. It is still most common to apply the vaccination rate to the…

Populations and Evolution · Quantitative Biology 2026-03-09 Glenn Ledder

Capture-recapture (CRC) surveys are used to estimate the size of a population whose members cannot be enumerated directly. CRC surveys have been used to estimate the number of Covid-19 infections, people who use drugs, sex workers, conflict…

Methodology · Statistics 2022-10-17 Jinghao Sun , Luk Van Baelen , Els Plettinckx , Forrest W. Crawford

Motivated by massive outbreaks of COVID-19 that occurred even in populations with high vaccine uptake, we propose a novel multi-population temporal network model for the spread of recurrent epidemic diseases. We study the effect of human…

Dynamical Systems · Mathematics 2022-09-19 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The COVID-19 lockdowns have created a significant socioeconomic impact on our society. In this paper, we propose a population vaccination game framework, called EPROACH, to design policies for reopenings that guarantee post-opening public…

Computer Science and Game Theory · Computer Science 2021-10-14 Shutian Liu , Quanyan Zhu

Incorporating social factors into disease prevention and control efforts is an important undertaking of behavioral epidemiology. The interplay between disease transmission and human health behaviors, such as vaccine uptake, results in…

Physics and Society · Physics 2023-02-16 Marzena Fügenschuh , Feng Fu

Motivated by the increasing number of COVID-19 cases that have been observed in many countries after the vaccination and relaxation of non-pharmaceutical interventions, we propose a mathematical model on time-varying networks for the spread…

Dynamical Systems · Mathematics 2022-03-09 Kathinka Frieswijk , Lorenzo Zino , Ming Cao

The resurgence of measles is largely attributed to the decline in vaccine adoption and the increase in mobility. Although the vaccine for measles is readily available and highly successful, its current adoption is not adequate to prevent…

Populations and Evolution · Quantitative Biology 2020-08-26 Sheryl L. Chang , Mahendra Piraveenan , Mikhail Prokopenko

We estimate patterns of covariation between COVID-19 vaccination rates and a set of widely used indicators of human, social, and economic capital across 146 countries in July 2021 and February 2022. About 70% of the variability in COVID-19…

Physics and Society · Physics 2022-03-02 Cosima Rughinis , Simona-Nicoleta Vulpe , Michael G. Flaherty , Sorina Vasile

Based on the information communicated in press releases, and finally published towards the end of 2020 by Pfizer, Moderna and AstraZeneca, we have built up a simple Bayesian model, in which the main quantity of interest plays the role of…

Applications · Statistics 2021-09-07 Giulio D'Agostini , Alfredo Esposito

This paper develops mathematical tools to estimate seasonal changes in measles transmission rates and corresponding variation in population susceptibility. The tools are designed to leverage times series of cases in the absence of…

Populations and Evolution · Quantitative Biology 2024-05-17 Niket Thakkar , Sonia Jindal , Katherine Rosenfeld

We investigate stochastic extinction in an epidemic model and the impact of random vaccinations in large populations formulated in terms of an optimal escape path. We find that different random vaccination strategies can have widely…

Biological Physics · Physics 2007-11-12 Alexandra S. Landsman , Ira B. Schwartz