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Deep learning algorithms require extensive data to achieve robust performance. However, data availability is often restricted in the medical domain due to patient privacy concerns. Synthetic data presents a possible solution to these…
Diffusion models (DMs) have achieved state-of-the-art results for image synthesis tasks as well as density estimation. Applied in the latent space of a powerful pretrained autoencoder (LDM), their immense computational requirements can be…
This paper studies 3D low-dose computed tomography (CT) imaging. Although various deep learning methods were developed in this context, typically they focus on 2D images and perform denoising due to low-dose and deblurring for…
Image deblurring is an ill-posed problem with multiple plausible solutions for a given input image. However, most existing methods produce a deterministic estimate of the clean image and are trained to minimize pixel-level distortion. These…
Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…
Denoising Diffusion Probabilistic Models (DDPMs) show promising potential in one-step Real-World Image Super-Resolution (Real-ISR). Current one-step Real-ISR methods typically inject the low-quality (LQ) image latent representation at the…
Low-dose Positron Emission Tomography (PET) reduces radiation exposure but suffers from severe noise and quantitative degradation. Diffusion-based denoising models achieve strong final reconstructions, yet their reverse trajectories are…
Ultra-high resolution images are desirable in photon counting CT (PCCT), but resolution is physically limited by interactions such as charge sharing. Deep learning is a possible method for super-resolution (SR), but sourcing paired training…
Self-supervised learning (SSL) and diffusion models have advanced representation learning and image synthesis, but in 3D medical imaging they are still largely used separately for analysis and synthesis, respectively. Unifying them is…
Machine learning in neurosurgery is limited by challenges in assembling large, high-quality imaging datasets. Synthetic data offers a scalable, privacy-preserving solution. We evaluated the feasibility of generating realistic lateral…
Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…
Multimodal medical image fusion (MMIF) extracts the most meaningful information from multiple source images, enabling a more comprehensive and accurate diagnosis. Achieving high-quality fusion results requires a careful balance of…
Despite its success in image synthesis, we observe that diffusion probabilistic models (DPMs) often lack contextual reasoning ability to learn the relations among object parts in an image, leading to a slow learning process. To solve this…
Multimodal Magnetic Resonance (MR) Imaging plays a crucial role in disease diagnosis due to its ability to provide complementary information by analyzing a relationship between multimodal images on the same subject. Acquiring all MR…
Semantic image synthesis (SIS) is a task to generate realistic images corresponding to semantic maps (labels). However, in real-world applications, SIS often encounters noisy user inputs. To address this, we propose Stochastic Conditional…
Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…
Multi-modality image fusion aims to combine different modalities to produce fused images that retain the complementary features of each modality, such as functional highlights and texture details. To leverage strong generative priors and…
Background: Rim+ lesions in multiple sclerosis (MS), detectable via Quantitative Susceptibility Mapping (QSM), correlate with increased disability. Existing literature lacks quantitative analysis of these lesions. We introduce RimSet for…
The generative priors of pre-trained latent diffusion models (DMs) have demonstrated great potential to enhance the visual quality of image super-resolution (SR) results. However, the noise sampling process in DMs introduces randomness in…
Three-dimensional (3D) medical image enhancement, including denoising and super-resolution, is critical for clinical diagnosis in CT, PET, and MRI. Although diffusion models have shown remarkable success in 2D medical imaging, scaling them…