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Accurate prediction of malignancy in renal tumors is crucial for informing clinical decisions and optimizing treatment strategies. However, existing imaging modalities lack the necessary accuracy to reliably predict malignancy before…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Zhengkang Fan , Chengkun Sun , Russell Terry , Jie Xu , Longin Jan Latecki

We consider preoperative prediction of thyroid cancer based on ultra-high-resolution whole-slide cytopathology images. Inspired by how human experts perform diagnosis, our approach first identifies and classifies diagnostic image regions…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 David Dov , Shahar Kovalsky , Jonathan Cohen , Danielle Range , Ricardo Henao , Lawrence Carin

Lung cancer is a leading cause of cancer-related deaths worldwide, and early detection is crucial for improving patient outcomes. Nevertheless, early diagnosis of cancer is a major challenge, particularly in low-resource settings where…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Samiul Based Shuvo , Tasnia Binte Mamun

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Recent evolution in deep learning has proven its value for CT-based lung nodule classification. Most current techniques are intrinsically black-box systems, suffering from two generalizability issues in clinical practice. First,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-28 Hanxiao Zhang , Liang Chen , Xiao Gu , Minghui Zhang , Yulei Qin , Feng Yao , Zhexin Wang , Yun Gu , Guang-Zhong Yang

Thyroid disorders are most commonly diagnosed using high-resolution Ultrasound (US). Longitudinal nodule tracking is a pivotal diagnostic protocol for monitoring changes in pathological thyroid morphology. This task, however, imposes a…

Image and Video Processing · Electrical Eng. & Systems 2023-09-04 Lennart Bastian , Vincent Bürgin , Ha Young Kim , Alexander Baumann , Benjamin Busam , Mahdi Saleh , Nassir Navab

Introduction: Deep learning-based segmentation models are increasingly integrated into clinical imaging workflows, yet their robustness to adversarial perturbations remains incompletely characterized, particularly for ultrasound images. We…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Nicholas Dietrich , David McShannon

Lung cancer ranks as one of the leading causes of cancer diagnosis and is the foremost cause of cancer-related mortality worldwide. The early detection of lung nodules plays a pivotal role in improving outcomes for patients, as it enables…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Jiasen Zhang , Mingrui Yang , Weihong Guo , Brian A. Xavier , Michael Bolen , Xiaojuan Li

Machine learning (ML) for diagnosis of thyroid nodules on ultrasound is an active area of research. However, ML tools require large, well-labelled datasets, the curation of which is time-consuming and labor-intensive. The purpose of our…

Image and Video Processing · Electrical Eng. & Systems 2023-05-05 Jikai Zhang , Maciej M. Mazurowski , Brian C. Allen , Benjamin Wildman-Torbiner

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Thyroid ultrasound is the first-line exam for assessing thyroid nodules and determining whether biopsy is warranted. In routine reporting, radiologists produce two coupled outputs: a nodule contour for measurement and a TI-RADS risk…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Dina Salama , Mohamed Mahmoud , Nourhan Bayasi , David Liu , Ilker Hacihaliloglu

Accurate detection of ultrasound nodules is essential for the early diagnosis and treatment of thyroid and breast cancers. However, this task remains challenging due to irregular nodule shapes, indistinct boundaries, substantial scale…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jingjing Wang , Zhuo Xiao , Xinning Yao , Bo Liu , Lijuan Niu , Xiangzhi Bai , Fugen Zhou

Lung cancer is the leading cause of patient mortality in the world. Early diagnosis of malignant pulmonary nodules in CT images can have a significant impact on reducing disease mortality and morbidity. In this work, we propose LMLCC-Net, a…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Tasnia Binte Mamun , Adhora Madhuri , Nusaiba Sobir , Taufiq Hasan

The incidence of thyroid nodule is very high and generally increases with the age. Thyroid nodule may presage the emergence of thyroid cancer. The thyroid nodule can be completely cured if detected early. Fine needle aspiration cytology is…

Computer Vision and Pattern Recognition · Computer Science 2012-11-06 Jie Zhao , Wei Zheng , Li Zhang , Hua Tian

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Ultrasound imaging is generally employed for real-time investigation of internal anatomy of the human body for disease identification. Delineation of the anatomical boundary of organs and pathological lesions is quite challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-23 Sumanth Nandamuri , Debarghya China , Pabitra Mitra , Debdoot Sheet

In order to optimize the radiotherapy delivery for cancer treatment, especially when dealing with complex treatments such as Total Marrow and Lymph Node Irradiation (TMLI), the accurate contouring of the Planning Target Volume (PTV) is…

Computer Vision and Pattern Recognition · Computer Science 2024-02-12 Ricardo Coimbra Brioso , Damiano Dei , Nicola Lambri , Daniele Loiacono , Pietro Mancosu , Marta Scorsetti

Deep learning (DL) models for disease classification or segmentation from medical images are increasingly trained using transfer learning (TL) from unrelated natural world images. However, shortcomings and utility of TL for specialized…

Machine Learning · Statistics 2021-11-11 Sambuddha Ghosal , Pratik Shah

This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…