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Motivated by the hypothesis that neural network representations encode abstract, interpretable features as linearly accessible, approximately orthogonal directions, sparse autoencoders (SAEs) have become a popular tool in interpretability.…

Machine Learning · Computer Science 2025-11-05 Valérie Costa , Thomas Fel , Ekdeep Singh Lubana , Bahareh Tolooshams , Demba Ba

In many scientific fields, researchers are interested in discovering features with substantial effect on the response from a large number of features while controlling the proportion of false discoveries. By incorporating the knockoff…

Methodology · Statistics 2023-02-28 Jiaqi Gu , Guosheng Yin

We study the challenge of achieving theoretically grounded feature recovery using Sparse Autoencoders (SAEs) for the interpretation of Large Language Models. Existing SAE training algorithms often lack rigorous mathematical guarantees and…

Machine Learning · Computer Science 2025-06-18 Siyu Chen , Heejune Sheen , Xuyuan Xiong , Tianhao Wang , Zhuoran Yang

RFdiffusion is a popular and well-established model for generation of protein structures. However, this generative process offers limited insight into its internal representations and how they contribute to the final protein structure.…

Quantitative Methods · Quantitative Biology 2025-12-01 Wojciech Zarzecki , Paulina Szymczak , Ewa Szczurek , Kamil Deja

Modern LLMs face inference efficiency challenges due to their scale. To address this, many compression methods have been proposed, such as pruning and quantization. However, the effect of compression on a model's interpretability remains…

Machine Learning · Computer Science 2025-07-23 Suchit Gupte , Vishnu Kabir Chhabra , Mohammad Mahdi Khalili

Sparse autoencoders (SAEs) are now standard tools for decomposing language model activations into interpretable features, and automated interpretability pipelines routinely assign each feature a short natural-language explanation. Existing…

Machine Learning · Computer Science 2026-05-14 Jordan F. McCann

Sparse autoencoders (SAEs) promise a unified approach for mechanistic interpretability, concept discovery, and model steering in LLMs and LVLMs. However, realizing this potential requires learned features to be both interpretable and…

Machine Learning · Computer Science 2026-04-01 Akshay Kulkarni , Tsui-Wei Weng , Vivek Narayanaswamy , Shusen Liu , Wesam A. Sakla , Kowshik Thopalli

The goal of feature selection is to identify important features that are relevant to explain an outcome variable. Most of the work in this domain has focused on identifying globally relevant features, which are features that are related to…

Machine Learning · Statistics 2019-05-30 Jaime Roquero Gimenez , James Zou

For large language models (LLMs), sparse autoencoders (SAEs) have been shown to decompose intermediate representations that often are not interpretable directly into sparse sums of interpretable features, facilitating better control and…

The recent proliferation of high-dimensional data, such as electronic health records and genetics data, offers new opportunities to find novel predictors of outcomes. Presented with a large set of candidate features, interest often lies in…

Methodology · Statistics 2024-09-24 Michael J. Martens , Anjishnu Banerjee , Xinran Qi , Yushu Shi

We introduce sparse autoencoder neural operators (SAE-NOs), a new class of sparse autoencoders that operate in function spaces rather than fixed-dimensional Euclidean representations. We formalize the functional representation hypothesis,…

Machine Learning · Computer Science 2026-05-11 Bahareh Tolooshams , Ailsa Shen , Anima Anandkumar

Deterministically controlling the target generation language of large multilingual language models (LLMs) remains a fundamental challenge, particularly in zero-shot settings where neither explicit language prompts nor fine-tuning are…

Computation and Language · Computer Science 2025-10-17 Cheng-Ting Chou , George Liu , Jessica Sun , Cole Blondin , Kevin Zhu , Vasu Sharma , Sean O'Brien

Stability and reproducibility are essential considerations in various applications of statistical methods. False Discovery Rate (FDR) control methods are able to control false signals in scientific discoveries. However, many FDR control…

Methodology · Statistics 2025-12-22 Jiajun Sun , Zhanrui Cai , Wei Zhong

Large Language Models (LLMs) have transformed natural language processing, yet their internal mechanisms remain largely opaque. Recently, mechanistic interpretability has attracted significant attention from the research community as a…

Machine Learning · Computer Science 2025-09-24 Dong Shu , Xuansheng Wu , Haiyan Zhao , Daking Rai , Ziyu Yao , Ninghao Liu , Mengnan Du

The increasing availability of data has generated unprecedented prospects for network analyses in many biological fields, such as neuroscience (e.g., brain networks), genomics (e.g., gene-gene interaction networks), and ecology (e.g.,…

Methodology · Statistics 2021-02-05 Lu Yu , Tobias Kaufmann , Johannes Lederer

Sparse autoencoders (SAEs) are commonly used to interpret the internal activations of large language models (LLMs) by mapping them to human-interpretable concept representations. While existing evaluations of SAEs focus on metrics such as…

Machine Learning · Computer Science 2026-01-26 Aaron J. Li , Suraj Srinivas , Usha Bhalla , Himabindu Lakkaraju

Sparse auto-encoders (SAEs) have re-emerged as a prominent method for mechanistic interpretability, yet they face two significant challenges: the non-smoothness of the $L_1$ penalty, which hinders reconstruction and scalability, and a lack…

Artificial Intelligence · Computer Science 2026-05-19 Ouns El Harzli , Hugo Wallner , Yoonsoo Nam , Haixuan Xavier Tao

Sparse autoencoders (SAEs) have been widely used for interpretability of neural networks, but their learned features often vary across seeds and hyperparameter settings. We introduce Ordered Sparse Autoencoders (OSAE), which extend…

Machine Learning · Computer Science 2025-12-03 Sophie L. Wang , Alex Quach , Nithin Parsan , John J. Yang

Sparse Autoencoders (SAEs) have emerged as a useful tool for interpreting the internal representations of neural networks. However, naively optimising SAEs for reconstruction loss and sparsity results in a preference for SAEs that are…

Machine Learning · Computer Science 2024-10-16 Kola Ayonrinde , Michael T. Pearce , Lee Sharkey

Radiological services are experiencing unprecedented demand, leading to increased interest in automating radiology report generation. Existing Vision-Language Models (VLMs) suffer from hallucinations, lack interpretability, and require…

Computer Vision and Pattern Recognition · Computer Science 2024-10-07 Ahmed Abdulaal , Hugo Fry , Nina Montaña-Brown , Ayodeji Ijishakin , Jack Gao , Stephanie Hyland , Daniel C. Alexander , Daniel C. Castro
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