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As machine learning models become increasingly integrated into healthcare, structural inequities and social biases embedded in clinical data can be perpetuated or even amplified by data-driven models. In survival analysis, censoring and…

The heterogeneous treatment effect plays a crucial role in precision medicine.There is evidence that real-world data, even subject to biases, can be employed as supplementary evidence for randomized clinical trials to improve the…

Methodology · Statistics 2025-09-04 Guangcai Mao , Shu Yang , Xiaofei Wang

We investigate two population-level quantities (corresponding to complete data) related to uncensored stage waiting times in a progressive multi-stage model, conditional on a prior stage visit. We show how to estimate these quantities…

Methodology · Statistics 2025-04-25 Xiaoxi Zhang , Peihua Qiu , Somnath Datta

We obtain a reliability acceptance sampling plan for independent competing risk data under interval censoring schemes using the Bayesian approach. At first, the Bayesian reliability acceptance sampling plan is obtained where the decision…

Applications · Statistics 2025-10-21 Biswabrata Pradhan , Rathin Das

Simulation models of critical systems often have parameters that need to be calibrated using observed data. For expensive simulation models, calibration is done using an emulator of the simulation model built on simulation output at…

Methodology · Statistics 2023-08-24 Özge Sürer , Matthew Plumlee , Stefan M. Wild

We propose a restricted win probability estimand for comparing treatments in a randomized trial with a time-to-event outcome. We also propose Bayesian estimators for this summary measure as well as the unrestricted win probability. Bayesian…

Methodology · Statistics 2024-11-06 Michelle Leeberg , Xianghua Luo , Thomas A. Murray

In many stochastic service systems, decision-makers find themselves making a sequence of decisions, with the number of decisions being unpredictable. To enhance these decisions, it is crucial to uncover the causal impact these decisions…

Methodology · Statistics 2023-07-18 Juan C. David Gomez , Amy L. Cochran , Gabriel Zayas-Caban

Feedforward neural networks (FNNs) can be viewed as non-linear regression models, where covariates enter the model through a combination of weighted summations and non-linear functions. Although these models have some similarities to the…

Methodology · Statistics 2024-05-02 Andrew McInerney , Kevin Burke

In active surveillance of prostate cancer, cancer progression is interval-censored and the examination to detect progression is subject to misclassification, usually false negatives. Meanwhile, patients may initiate early treatment before…

This study examines the application of Bayesian approach in the context of clinical trials, emphasizing their increasing importance in contemporary biomedical research. While conventional frequentist approach provides a foundational basis…

Methodology · Statistics 2026-01-16 Paramahansa Pramanik , Arnab Kumar Maity , Anjan Mandal , Haley Kate Robinson

This paper presents an algorithm which aims to assist the radiologist in identifying breast cancer at its earlier stages. It combines several image processing techniques like image negative, thresholding and segmentation techniques for…

Computer Vision and Pattern Recognition · Computer Science 2009-11-04 Y. Ireaneus Anna Rejani , S. Thamarai Selvi

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Improving health worldwide will require rigorous quantification of population-level trends in health status. However, global-level surveys are not available, forcing researchers to rely on fragmentary country-specific data of varying…

Methodology · Statistics 2014-05-20 Mariel M. Finucane , Christopher J. Paciorek , Goodarz Danaei , Majid Ezzati

Assessing causal effects in the presence of unobserved confounding is a challenging problem. Existing studies leveraged proxy variables or multiple treatments to adjust for the confounding bias. In particular, the latter approach attributes…

Methodology · Statistics 2023-10-17 Yong Wu , Mingzhou Liu , Jing Yan , Yanwei Fu , Shouyan Wang , Yizhou Wang , Xinwei Sun

In social and biomedical sciences testing in contingency tables often involves order restrictions on cell-probabilities parameters. We develop objective Bayes methods for order-constrained testing and model comparison when observations…

Methodology · Statistics 2018-10-24 Roberta Paroli , Guido Consonni

We consider survival data that combine three types of observations: uncensored, right-censored, and left-censored. Such data arises from screening a medical condition, in situations where self-detection arises naturally. Our goal is to…

Statistics Theory · Mathematics 2018-03-08 Jonathan Yefenof , Yair Goldberg , Jennifer Wiler , Avishai Mandelbaum , Ya'acov Ritov

We propose a Bayesian model selection approach that allows medical practitioners to select among predictor variables while taking their respective costs into account. Medical procedures almost always incur costs in time and/or money. These…

Methodology · Statistics 2024-05-07 Erica M. Porter , Christopher T. Franck , Stephen Adams

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

Methodology · Statistics 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Clinical trials or studies oftentimes require long-term and/or costly follow-up of participants to evaluate a novel treatment/drug/vaccine. There has been increasing interest in the past few decades in using short-term surrogate outcomes as…

Methodology · Statistics 2024-12-19 Xuan Wang , Tianxi Cai , Lu Tian , Layla Parast

In computational mechanics, multiple models are often present to describe a physical system. While Bayesian model selection is a helpful tool to compare these models using measurement data, it requires the computationally expensive…

Computation · Statistics 2025-04-14 Subhayan De , Reza Farzad , Patrick T. Brewick , Erik A. Johnson , Steven F. Wojtkiewicz