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Crystalline materials, with symmetrical and periodic structures, exhibit a wide spectrum of properties and have been widely used in numerous applications across electronics, energy, and beyond. For crystalline materials discovery,…

Computational Engineering, Finance, and Science · Computer Science 2026-02-11 Zhenzhong Wang , Haowei Hua , Wanyu Lin , Ming Yang , Kay Chen Tan

Discovering physical laws directly from high-dimensional visual data is a long-standing human pursuit but remains a formidable challenge for machines, representing a fundamental goal of scientific intelligence. This task is inherently…

Computational Engineering, Finance, and Science · Computer Science 2026-02-24 Ruikun Li , Jun Yao , Yingfan Hua , Shixiang Tang , Biqing Qi , Bin Liu , Wanli Ouyang , Yan Lu

Omics software tools have reshaped the landscape of modern biology and become an essential component of biomedical research. The increasing dependence of biomedical scientists on these powerful tools creates a need for easier installation…

Scalable and efficient numerical simulations continue to gain importance, as computation is firmly established as the third pillar of discovery, alongside theory and experiment. Meanwhile, the performance of computing hardware grows through…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Pietro Incardona , Antonio Leo , Yaroslav Zaluzhnyi , Rajesh Ramaswamy , Ivo F. Sbalzarini

Neuromorphic computing seeks to replicate the remarkable efficiency, flexibility, and adaptability of the human brain in artificial systems. Unlike conventional digital approaches, which suffer from the Von Neumann bottleneck and depend on…

Artificial Intelligence · Computer Science 2025-11-04 Marcel van Gerven

Artificial intelligence (AI) has sparked immense interest in drug discovery, but most current approaches only digitize existing high-throughput experiments. They remain constrained by conventional pipelines. As a result, they do not address…

Computers and Society · Computer Science 2025-07-29 You Wu , Philip E. Bourne , Lei Xie

With the increased interest in computational sciences, machine learning (ML), pattern recognition (PR) and big data, governmental agencies, academia and manufacturers are overwhelmed by the constant influx of new algorithms and techniques…

Software Engineering · Computer Science 2017-07-28 André Anjos , Laurent El-Shafey , Sébastien Marcel

Machine learning has revolutionized polymer science by enabling rapid property prediction and generative design. Large language models (LLMs) offer further opportunities in polymer informatics by simplifying workflows that traditionally…

Computational Engineering, Finance, and Science · Computer Science 2026-02-20 Sonakshi Gupta , Akhlak Mahmood , Shivank Shukla , Rampi Ramprasad

Deploying robots at scale demands robustness to the long tail of everyday situations. The countless variations in scene layout, object geometry, and task specifications that characterize real environments are vast and underrepresented in…

Twenty-five years ago the desktop computer started becoming ubiquitous in the scientific lab. Researchers were delighted with its ability to both control instrumentation and acquire data on a single system, but they were not completely…

Digital Libraries · Computer Science 2014-03-12 Robert R. White , Kristin Munch

Computational methods that operate on three-dimensional molecular structure have the potential to solve important questions in biology and chemistry. In particular, deep neural networks have gained significant attention, but their…

Large-scale atomistic simulations are essential to bridge computational materials and chemistry to realistic materials and drug discovery applications. In the past few years, rapid developments of machine learning interatomic potentials…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-02-03 Kevin Han , Bowen Deng , Amir Barati Farimani , Gerbrand Ceder

Recent advances in generative AI have accelerated the discovery of novel chemicals and materials. However, scaling these discoveries to industrial production remains a major bottleneck due to the synthesis gap -- the need to develop…

Machine Learning · Computer Science 2025-08-19 Sakhinana Sagar Srinivas , Shivam Gupta , Venkataramana Runkana

Recent advancements in artificial intelligence have sparked interest in scientific assistants that could support researchers across the full spectrum of scientific workflows, from literature review to experimental design and data analysis.…

Different aspects of a clinical sample can be revealed by multiple types of omics data. Integrated analysis of multi-omics data provides a comprehensive view of patients, which has the potential to facilitate more accurate clinical decision…

Machine Learning · Computer Science 2020-02-11 Xiaoyu Zhang , Jingqing Zhang , Kai Sun , Xian Yang , Chengliang Dai , Yike Guo

The development of artificial intelligence (AI) and robotics are both based on the tenet of "science and technology are people-oriented", and both need to achieve efficient communication with the human brain. Based on multi-disciplinary…

Neurons and Cognition · Quantitative Biology 2024-06-27 Shengjie Zheng , Ling Liu , Junjie Yang , Jianwei Zhang , Tao Su , Bin Yue , Xiaojian Li

Large Language Models are versatile, general-purpose tools with a wide range of applications. Recently, the advent of "reasoning models" has led to substantial improvements in their abilities in advanced problem-solving domains such as…

Machine Learning · Computer Science 2025-07-14 Nicholas T. Runcie , Charlotte M. Deane , Fergus Imrie

The development of machine-learning models for atomic-scale simulations has benefited tremendously from the large databases of materials and molecular properties computed in the past two decades using electronic-structure calculations. More…

The physical implementation of artificial intelligence requires mapping computational processes onto the dynamic physical processes of the underlying computing platform. The photonic processors offer an intrinsically parallel and low energy…

As models become increasingly sophisticated, conventional algorithm benchmarks are increasingly saturated, underscoring the need for more challenging benchmarks to guide future improvements in algorithmic reasoning. This paper introduces…

Artificial Intelligence · Computer Science 2025-06-13 Yaoming Zhu , Junxin Wang , Yiyang Li , Lin Qiu , ZongYu Wang , Jun Xu , Xuezhi Cao , Yuhuai Wei , Mingshi Wang , Xunliang Cai , Rong Ma