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Acquiring pixel-level annotations is often limited in applications such as histology studies that require domain expertise. Various semi-supervised learning approaches have been developed to work with limited ground truth annotations, such…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Qiangguo Jin , Hui Cui , Changming Sun , Yang Song , Jiangbin Zheng , Leilei Cao , Leyi Wei , Ran Su

Biomedical imaging is a driver of scientific discovery and core component of medical care, currently stimulated by the field of deep learning. While semantic segmentation algorithms enable 3D image analysis and quantification in many…

Computer Vision and Pattern Recognition · Computer Science 2020-12-09 Fabian Isensee , Paul F. Jäger , Simon A. A. Kohl , Jens Petersen , Klaus H. Maier-Hein

Lung cancer has been one of the major threats across the world with the highest mortalities. Computer-aided detection (CAD) can help in early detection and thus can help increase the survival rate. Accurate lung parenchyma segmentation (to…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Muhammad Abdullah , Furqan Shaukat

Uncertainty quantification is crucial for the deployment of image restoration models in safety-critical domains, like autonomous driving and biological imaging. To date, methods for uncertainty visualization have mainly focused on per-pixel…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Elias Nehme , Omer Yair , Tomer Michaeli

Accurate diagnosis and treatment of complex diseases require integrating histological, molecular, and clinical data, yet in practice these modalities are often incomplete owing to tissue scarcity, assay cost, and workflow constraints.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Jinxi Xiang , Mingjie Li , Siyu Hou , Yijiang Chen , Xiangde Luo , Yuanfeng Ji , Xiang Zhou , Ehsan Adeli , Akshay Chaudhari , Curtis P. Langlotz , Kilian M. Pohl , Ruijiang Li

In this work we present a method for lung nodules segmentation, their texture classification and subsequent follow-up recommendation from the CT image of lung. Our method consists of neural network model based on popular U-Net architecture…

Image and Video Processing · Electrical Eng. & Systems 2020-06-29 Alexandr G. Rassadin

3D microscopy is key in the investigation of diverse biological systems, and the ever increasing availability of large datasets demands automatic cell identification methods that not only are accurate, but also can imply the uncertainty in…

Computer Vision and Pattern Recognition · Computer Science 2021-02-24 Alvaro Gomariz , Tiziano Portenier , César Nombela-Arrieta , Orcun Goksel

We introduce Post-DAE, a post-processing method based on denoising autoencoders (DAE) to improve the anatomical plausibility of arbitrary biomedical image segmentation algorithms. Some of the most popular segmentation methods (e.g. based on…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Agostina J Larrazabal , César Martínez , Ben Glocker , Enzo Ferrante

Accurate segmentation of the prostate gland in multiparametric MRI (mpMRI) is a fundamental step for a wide range of clinical and research applications, including image registration, volume estimation, and radiomic analysis. However, manual…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Pablo Rodriguez-Belenguer , Gloria Ribas , Javier Aquerreta Escribano , Rafael Moreno-Calatayud , Leonor Cerda-Alberich , Luis Marti-Bonmati

Each medical segmentation task should be considered with a specific AI algorithm based on its scenario so that the most accurate prediction model can be obtained. The most popular algorithms in medical segmentation, 3D U-Net and its…

Computer Vision and Pattern Recognition · Computer Science 2024-02-13 Shiyi Wang , Yang Nan , Felder Federico N , Sheng Zhang , Walsh Simon L F , Guang Yang

Developing clinically useful cell-level analysis tools in digital pathology remains challenging due to limitations in dataset granularity, inconsistent annotations, high computational demands, and difficulties integrating new technologies…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Nikita Shvetsov , Thomas K. Kilvaer , Masoud Tafavvoghi , Anders Sildnes , Kajsa Møllersen , Lill-Tove Rasmussen Busund , Lars Ailo Bongo

Clinical data elements (CDEs) (e.g., age, smoking history), blood markers and chest computed tomography (CT) structural features have been regarded as effective means for assessing lung cancer risk. These independent variables can provide…

Image and Video Processing · Electrical Eng. & Systems 2021-02-11 Riqiang Gao , Yucheng Tang , Kaiwen Xu , Michael N. Kammer , Sanja L. Antic , Steve Deppen , Kim L. Sandler , Pierre P. Massion , Yuankai Huo , Bennett A. Landman

Multimodal MRI provides critical complementary information for accurate brain tumor segmentation. However, conventional methods struggle when certain modalities are missing due to issues such as image quality, protocol inconsistencies,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Runze Cheng , Xihang Qiu , Ming Li , Ye Zhang , Chun Li , Fei Yu

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowledge, and are often considered as a "black-box." The lack of…

Computer Vision and Pattern Recognition · Computer Science 2018-06-05 Shiwen Shen , Simon X. Han , Denise R. Aberle , Alex A. T. Bui , Willliam Hsu

Segmentation of anatomical structures and pathologies is inherently ambiguous. For instance, structure borders may not be clearly visible or different experts may have different styles of annotating. The majority of current state-of-the-art…

The early detection of a pulmonary embolism (PE) is critical for enhancing patient survival rates. Both image-based and non-image-based features are of utmost importance in medical classification tasks. In a clinical setting, physicians…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Zhaoxin Guo , Zhipeng Wang , Ruiquan Ge , Jianxun Yu , Feiwei Qin , Yuan Tian , Yuqing Peng , Yonghong Li , Changmiao Wang

We present a deep learning framework for probabilistic pixel-wise semantic segmentation, which we term Bayesian SegNet. Semantic segmentation is an important tool for visual scene understanding and a meaningful measure of uncertainty is…

Computer Vision and Pattern Recognition · Computer Science 2016-10-12 Alex Kendall , Vijay Badrinarayanan , Roberto Cipolla

Automated lesion segmentation in PET/CT scans is crucial for improving clinical workflows and advancing cancer diagnostics. However, the task is challenging due to physiological variability, different tracers used in PET imaging, and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Maximilian Rokuss , Balint Kovacs , Yannick Kirchhoff , Shuhan Xiao , Constantin Ulrich , Klaus H. Maier-Hein , Fabian Isensee

The distribution of the weights of modern deep neural networks (DNNs) - crucial for uncertainty quantification and robustness - is an eminently complex object due to its extremely high dimensionality. This paper proposes one of the first…

Machine Learning · Statistics 2023-10-13 Olivier Laurent , Emanuel Aldea , Gianni Franchi

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu