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The tumor immune microenvironment (TIME) in non-small cell lung cancer (NSCLC) histopathology contains morphological and molecular characteristics predictive of immunotherapy response. Computational quantification of TIME characteristics,…

End-to-End (E2E) unrolled optimization frameworks show promise for Magnetic Resonance (MR) image recovery, but suffer from high memory usage during training. In addition, these deterministic approaches do not offer opportunities for…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Jyothi Rikhab Chand , Mathews Jacob

Purpose: Optical imaging is evolving as a key technique for advanced sensing in the operating room. Recent research has shown that machine learning algorithms can be used to address the inverse problem of converting pixel-wise multispectral…

H-score is a semi-quantitative method used to assess the presence and distribution of proteins in tissue samples by combining the intensity of staining and percentage of stained nuclei. It is widely used but time-consuming and can be…

It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Peide Zhu , Linbin Lu , Zhiqin Chen , Xiong Chen

Head pose estimation (HPE) plays a critical role in various computer vision applications such as human-computer interaction and facial recognition. In this paper, we propose a novel deep learning approach for head pose estimation with…

Computer Vision and Pattern Recognition · Computer Science 2025-07-25 Mahdi Ghafourian , Federico M. Sukno

Background: In medical imaging, images are usually treated as deterministic, while their uncertainties are largely underexplored. Purpose: This work aims at using deep learning to efficiently estimate posterior distributions of imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

Biomedical image segmentation is a critical task in medical diagnosis and treatment planning, enabling precise delineation of anatomical structures and pathological regions. Despite significant advancements, challenges persist due to the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Joao Batista Florindo , Amanda Pontes de Oliveira Ornelas

In image segmentation, there is often more than one plausible solution for a given input. In medical imaging, for example, experts will often disagree about the exact location of object boundaries. Estimating this inherent uncertainty and…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Miguel Monteiro , Loïc Le Folgoc , Daniel Coelho de Castro , Nick Pawlowski , Bernardo Marques , Konstantinos Kamnitsas , Mark van der Wilk , Ben Glocker

Accurate medical image segmentation is crucial for diagnosis and analysis. However, the models without calibrated uncertainty estimates might lead to errors in downstream analysis and exhibit low levels of robustness. Estimating the…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Yanwu Yang , Xutao Guo , Yiwei Pan , Pengcheng Shi , Haiyan Lv , Ting Ma

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

Deep learning-based segmentation methods are widely utilized for detecting lesions in ultrasound images. Throughout the imaging procedure, the attenuation and scattering of ultrasound waves cause contour blurring and the formation of…

Image and Video Processing · Electrical Eng. & Systems 2024-11-22 Ruiguo Yu , Yiyang Zhang , Yuan Tian , Zhiqiang Liu , Xuewei Li , Jie Gao

Stochastic infectious disease models capture uncertainty in public health outcomes and have become increasingly popular in epidemiological practice. However, calibrating these models to observed data is challenging with existing methods for…

Methodology · Statistics 2024-12-18 Prayag Chatha , Fan Bu , Jeffrey Regier , Evan Snitkin , Jon Zelner

With the advent of advancements in deep learning approaches, such as deep convolution neural network, residual neural network, adversarial network; U-Net architectures are most widely utilized in biomedical image segmentation to address the…

Image and Video Processing · Electrical Eng. & Systems 2022-03-03 Narinder Singh Punn , Sonali Agarwal

Accurate classification of pediatric central nervous system tumors remains challenging due to histological complexity and limited training data. While pathology foundation models have advanced whole-slide image (WSI) analysis, they often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Jian Yu , Joakim Nguyen , Jinrui Fang , Awais Naeem , Zeyuan Cao , Sanjay Krishnan , Nicholas Konz , Tianlong Chen , Chandra Krishnan , Hairong Wang , Edward Castillo , Ying Ding , Ankita Shukla

There has been growing research interest in using deep learning based method to achieve fully automated segmentation of lesion in Positron emission tomography computed tomography(PET CT) scans for the prognosis of various cancers. Recent…

Image and Video Processing · Electrical Eng. & Systems 2022-09-19 Jia Zhang , Yukun Huang , Zheng Zhang , Yuhang Shi

Histology images with multi-gigapixel of resolution yield rich information for cancer diagnosis and prognosis. Most of the time, only slide-level label is available because pixel-wise annotation is labour intensive task. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2022-09-08 Made Satria Wibawa , Kwok-Wai Lo , Lawrence Young , Nasir Rajpoot

Accurate uncertainty estimation is a critical challenge in open-set recognition, where a probe biometric sample may belong to an unknown identity. It can be addressed through sample quality estimation via probabilistic embeddings. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Leonid Erlygin , Alexey Zaytsev

The ability to reconstruct high-quality images from undersampled MRI data is vital in improving MRI temporal resolution and reducing acquisition times. Deep learning methods have been proposed for this task, but the lack of verified methods…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Samah Khawaled , Moti Freiman

Ophthalmic image segmentation serves as a critical foundation for ocular disease diagnosis. Although fully convolutional neural networks (CNNs) are commonly employed for segmentation, they are constrained by inductive biases and face…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Zunjie Xiao , Xiaoqing Zhang , Risa Higashita , Jiang Liu