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Scientific research demands sophisticated reasoning over multimodal data, a challenge especially prevalent in biology. Despite recent advances in multimodal large language models (MLLMs) for AI-assisted research, existing multimodal…

We present M$^3$-VQA, a novel knowledge-based Visual Question Answering (VQA) benchmark, to enhance the evaluation of multimodal large language models (MLLMs) in fine-grained multimodal entity understanding and complex multi-hop reasoning.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Jiatong Ma , Longteng Guo , Yuchen Liu , Zijia Zhao , Dongze Hao , Xuanxu Lin , Jing Liu

Multimodal large language models (MLLMs) show remarkable potential for scientific reasoning, yet their performance in specialized domains such as microscopy remains limited by the scarcity of domain-specific training data and the difficulty…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Manyu Li , Ruian He , Chenxi Ma , Weimin Tan , Bo Yan

With the advent of multi-modal large language models (MLLMs), datasets used for visual question answering (VQA) and referring expression comprehension have seen a resurgence. However, the most popular datasets used to evaluate MLLMs are…

Artificial Intelligence · Computer Science 2024-08-13 Jian Lu , Shikhar Srivastava , Junyu Chen , Robik Shrestha , Manoj Acharya , Kushal Kafle , Christopher Kanan

Understanding the contents of multimodal documents is essential to accurately extract relevant evidence and use it for reasoning. Existing document understanding models tend to generate answers with a single word or phrase directly,…

Information Retrieval · Computer Science 2024-08-15 Jinxu Zhang

Large language models (LLMs) have demonstrated immense capabilities in understanding textual data and are increasingly being adopted to help researchers accelerate scientific discovery through knowledge extraction (information retrieval),…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Robinson Umeike , Neil Getty , Fangfang Xia , Rick Stevens

Real-world clinical practice demands multi-image comparative reasoning, yet current medical benchmarks remain limited to single-frame interpretation. We present MedFrameQA, the first benchmark explicitly designed to test multi-image medical…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Suhao Yu , Haojin Wang , Juncheng Wu , Luyang Luo , Jingshen Wang , Cihang Xie , Pranav Rajpurkar , Carl Yang , Yang Yang , Kang Wang , Yannan Yu , Yuyin Zhou

Multimodal/vision language models (VLMs) are increasingly being deployed in healthcare settings worldwide, necessitating robust benchmarks to ensure their safety, efficacy, and fairness. Multiple-choice question and answer (QA) datasets…

The emergence of Multimodal Large Language Models (MLLMs) that integrate vision and language modalities has unlocked new potentials for scientific reasoning, outperforming prior benchmarks in both natural language and coding domains.…

Computational Engineering, Finance, and Science · Computer Science 2025-05-27 Sifan Wu , Huan Zhang , Yizhan Li , Farshid Effaty , Amirreza Ataei , Bang Liu

Large language models perform well on many medical QA benchmarks, but real clinical reasoning often requires integrating evidence across multiple images rather than interpreting a single view. We introduce MedThinkVQA, an expert-annotated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Zonghai Yao , Benlu Wang , Yifan Zhang , Junda Wang , Iris Xia , Zhipeng Tang , Shuo Han , Feiyun Ouyang , Zhichao Yang , Arman Cohan , Hong Yu

Medical Visual Question Answering (VQA) enhances clinical decision-making by enabling systems to interpret medical images and answer clinical queries. However, developing efficient, high-performance VQA models is challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Belal Alsinglawi , Chris McCarthy , Sara Webb , Christopher Fluke , Navid Toosy Saidy

Explainability is critical for the clinical adoption of medical visual question answering (VQA) systems, as physicians require transparent reasoning to trust AI-generated diagnoses. We present MedXplain-VQA, a comprehensive framework…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Hai-Dang Nguyen , Minh-Anh Dang , Minh-Tan Le , Minh-Tuan Le

Medical vision-language models (VLMs) and AI agents have made significant progress in learning to analyze and reason about clinical images. However, existing medical visual question answering (VQA) benchmarks collapse model capabilities…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Yixiong Chen , Wenjie Xiao , Pedro R. A. S. Bassi , Boyan Wang , Liang He , Xinze Zhou , Sezgin Er , Ibrahim Ethem Hamamci , Zongwei Zhou , Alan Yuille

Integrating external tools into Large Foundation Models (LFMs) has emerged as a promising approach to enhance their problem-solving capabilities. While existing studies have demonstrated strong performance in tool-augmented Visual Question…

Artificial Intelligence · Computer Science 2026-03-05 Shaofeng Yin , Ting Lei , Yang Liu

Vision-Language Models (VLMs) have demonstrated remarkable capabilities in interpreting visual layouts and text. However, a significant challenge remains in their ability to interpret robustly and reason over multi-tabular data presented as…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Anshul Singh , Chris Biemann , Jan Strich

Multimodal Large Language Models (MLLMs) have demonstrated impressive abilities across various tasks, including visual question answering and chart comprehension, yet existing benchmarks for chart-related tasks fall short in capturing the…

Computation and Language · Computer Science 2025-02-11 Zifeng Zhu , Mengzhao Jia , Zhihan Zhang , Lang Li , Meng Jiang

While Multimodal Large Language Models (MLLMs) have experienced significant advancement in visual understanding and reasoning, their potential to serve as powerful, flexible, interpretable, and text-driven models for Image Quality…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Tianhe Wu , Kede Ma , Jie Liang , Yujiu Yang , Lei Zhang

Visual question answering (VQA) in medical imaging aims to support clinical diagnosis by automatically interpreting complex imaging data in response to natural language queries. Existing studies typically rely on distinct visual and textual…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Yuanhe Tian , Chen Su , Junwen Duan , Yan Song

Question decomposition has emerged as an effective strategy for prompting Large Language Models (LLMs) to answer complex questions. However, while existing methods primarily focus on unimodal language models, the question decomposition…

Computation and Language · Computer Science 2024-10-08 Haowei Zhang , Jianzhe Liu , Zhen Han , Shuo Chen , Bailan He , Volker Tresp , Zhiqiang Xu , Jindong Gu

Scientific reasoning is a key aspect of human intelligence, requiring the integration of multimodal inputs, domain expertise, and multi-step inference across various subjects. Existing benchmarks for multimodal large language models (MLLMs)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Longteng Guo , Xuanxu Lin , Dongze Hao , Tongtian Yue , Pengkang Huo , Jiatong Ma , Yuchen Liu , Jing Liu
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