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Foundational models are trained on extensive datasets to capture the general trends of a domain. However, in medical imaging, the scarcity of data makes pre-training for every domain, modality, or task challenging. Continual learning offers…

Image and Video Processing · Electrical Eng. & Systems 2025-08-20 Mohammad Areeb Qazi , Munachiso S Nwadike , Ibrahim Almakky , Mohammad Yaqub , Numan Saeed

Foundation models (FMs) have emerged as a transformative paradigm in medical image analysis, offering the potential to provide generalizable, task-agnostic solutions across a wide range of clinical tasks and imaging modalities. Their…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

Foundation models, large-scale, pre-trained deep-learning models adapted to a wide range of downstream tasks have gained significant interest lately in various deep-learning problems undergoing a paradigm shift with the rise of these…

Computer Vision and Pattern Recognition · Computer Science 2023-10-31 Bobby Azad , Reza Azad , Sania Eskandari , Afshin Bozorgpour , Amirhossein Kazerouni , Islem Rekik , Dorit Merhof

Recent advancements in artificial intelligence (AI), particularly foundation models (FMs), have revolutionized medical image analysis, demonstrating strong zero- and few-shot performance across diverse medical imaging tasks, from…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Praveenbalaji Rajendran , Mojtaba Safari , Wenfeng He , Mingzhe Hu , Shansong Wang , Jun Zhou , Xiaofeng Yang

Foundation models hold promise for transforming AI in healthcare by providing modular components that are easily adaptable to downstream healthcare tasks, making AI development more scalable and cost-effective. Structured EHR foundation…

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Modern medical records include a vast amount of multimodal free text clinical data and imaging data from radiology, cardiology, and digital pathology. Fully mining such big data requires multitasking; otherwise, occult but important aspects…

Image and Video Processing · Electrical Eng. & Systems 2024-04-25 Chuang Niu , Qing Lyu , Christopher D. Carothers , Parisa Kaviani , Josh Tan , Pingkun Yan , Mannudeep K. Kalra , Christopher T. Whitlow , Ge Wang

Accurate segmentation of organs and tumors in CT and MRI scans is essential for diagnosis, treatment planning, and disease monitoring. While deep learning has advanced automated segmentation, most models remain task-specific, lacking…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Yuheng Li , Yizhou Wu , Yuxiang Lai , Mingzhe Hu , Xiaofeng Yang

Foundation models (FMs) have shown transformative potential in radiology by performing diverse, complex tasks across imaging modalities. Here, we developed CT-FM, a large-scale 3D image-based pre-trained model designed explicitly for…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Suraj Pai , Ibrahim Hadzic , Dennis Bontempi , Keno Bressem , Benjamin H. Kann , Andriy Fedorov , Raymond H. Mak , Hugo J. W. L. Aerts

3D medical image classification is essential for modern clinical workflows. Medical foundation models (FMs) have emerged as a promising approach for scaling to new tasks, yet current research suffers from three critical pitfalls:…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Han Liu , Bogdan Georgescu , Yanbo Zhang , Youngjin Yoo , Michael Baumgartner , Riqiang Gao , Jianing Wang , Gengyan Zhao , Eli Gibson , Dorin Comaniciu , Sasa Grbic

Foundation models (FMs) are changing the way medical images are analyzed by learning from large collections of unlabeled data. Instead of relying on manually annotated examples, FMs are pre-trained to learn general-purpose visual features…

Foundation models refer to artificial intelligence (AI) models that are trained on massive amounts of data and demonstrate broad generalizability across various tasks with high accuracy. These models offer versatile, one-for-many or…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Rina Bao , Erfan Darzi , Sheng He , Chuan-Heng Hsiao , Mohammad Arafat Hussain , Jingpeng Li , Atle Bjornerud , Ellen Grant , Yangming Ou

Volumetric medical image segmentation is pivotal in enhancing disease diagnosis, treatment planning, and advancing medical research. While existing volumetric foundation models for medical image segmentation, such as SAM-Med3D and SegVol,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-15 Guoan Wang , Jin Ye , Junlong Cheng , Tianbin Li , Zhaolin Chen , Jianfei Cai , Junjun He , Bohan Zhuang

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Peirong Liu , Oula Puonti , Xiaoling Hu , Karthik Gopinath , Annabel Sorby-Adams , Daniel C. Alexander , W. Taylor Kimberly , Juan E. Iglesias

Promptable segmentation foundation models such as SAM3 have demonstrated strong generalization capabilities through interactive and concept-based prompting. However, their direct applicability to medical image segmentation remains limited…

Computer Vision and Pattern Recognition · Computer Science 2026-01-19 Chongcong Jiang , Tianxingjian Ding , Chuhan Song , Jiachen Tu , Ziyang Yan , Yihua Shao , Zhenyi Wang , Yuzhang Shang , Tianyu Han , Yu Tian

Foundation models (FMs) have demonstrated strong transferability across medical imaging tasks, yet their clinical utility depends critically on how pretrained representations are adapted to domain-specific data, supervision regimes, and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Karma Phuntsho , Abdullah , Kyungmi Lee , Ickjai Lee , Euijoon Ahn

Neural networks achieve state-of-the-art performance in many supervised learning tasks when the training data distribution matches the test data distribution. However, their performance drops significantly under domain (covariate) shift, a…

Computer Vision and Pattern Recognition · Computer Science 2024-09-13 Kerem Cekmeceli , Meva Himmetoglu , Guney I. Tombak , Anna Susmelj , Ertunc Erdil , Ender Konukoglu

Medical Foundation Models (MFMs), trained on large-scale datasets, have demonstrated superior performance across various tasks. However, these models still struggle with domain gaps in practical applications. Specifically, even after…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Jia-Xuan Jiang , Wenhui Lei , Yifeng Wu , Hongtao Wu , Furong Li , Yining Xie , Xiaofan Zhang , Zhong Wang

Foundation models leverage large-scale pretraining to capture extensive knowledge, demonstrating generalization in a wide range of language tasks. By comparison, vision foundation models (VFMs) often exhibit uneven improvements across…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Shiqi Huang , Yipei Wang , Natasha Thorley , Alexander Ng , Shaheer Saeed , Mark Emberton , Shonit Punwani , Veeru Kasivisvanathan , Dean Barratt , Daniel Alexander , Yipeng Hu
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