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Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…

Medical Physics · Physics 2023-03-07 Bijie Bai , Xilin Yang , Yuzhu Li , Yijie Zhang , Nir Pillar , Aydogan Ozcan

Pathology deals with the practice of discovering the reasons for disease by analyzing the body samples. The most used way in this field, is to use histology which is basically studying and viewing microscopic structures of cell and tissues.…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Virender Ranga , Shivam Gupta , Priyansh Agrawal , Jyoti Meena

With applications ranging from metabolomics to histopathology, quantitative phase microscopy (QPM) is a powerful label-free imaging modality. Despite significant advances in fast multiplexed imaging sensors and deep-learning-based inverse…

Digital holography is one of the most widely used label-free microscopy techniques in biomedical imaging. Recovery of the missing phase information of a hologram is an important step in holographic image reconstruction. Here we demonstrate…

Image and Video Processing · Electrical Eng. & Systems 2021-05-28 Luzhe Huang , Tairan Liu , Xilin Yang , Yi Luo , Yair Rivenson , Aydogan Ozcan

Medical imaging is an essential tool in many areas of medical applications, used for both diagnosis and treatment. However, reading medical images and making diagnosis or treatment recommendations require specially trained medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-13 Wentao Zhu

Detection of blood cells in microscopic images has become a major focus of medical image analysis, playing a crucial role in gaining valuable insights into a patient's health. Manual blood cell checks for disease detection are known to be…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ahmed Endris Hasen , Yang Shangming , Chiagoziem C. Ukwuoma , Biniyam Gashaw , Abel Zenebe Yutra

Recognizing various surgical tools, actions and phases from surgery videos is an important problem in computer vision with exciting clinical applications. Existing deep-learning-based methods for this problem either process each surgical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Haifeng Wang , Hao Xu , Jun Wang , Jian Zhou , Ke Deng

The imperative for early detection of type 2 diabetes mellitus (T2DM) is challenged by its asymptomatic onset and dependence on suboptimal clinical diagnostic tests, contributing to its widespread global prevalence. While research into…

Machine Learning · Computer Science 2024-12-17 Sanjana Gundapaneni , Zhuo Zhi , Miguel Rodrigues

Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. However, timely molecular diagnostic testing for patients with brain tumors is limited,…

Arterial spin labeling perfusion MRI is a noninvasive technique for measuring quantitative cerebral blood flow (CBF), but the measurement is subject to a low signal-to-noise-ratio(SNR). Various post-processing methods have been proposed to…

Computer Vision and Pattern Recognition · Computer Science 2018-01-31 Danfeng Xie , Li Bai , Ze Wang

Absolute quantification of biological samples entails determining expression levels in precise numerical copies, offering enhanced accuracy and superior performance for rare templates. However, existing methodologies suffer from significant…

Quantitative Methods · Quantitative Biology 2023-09-06 Yuanyuan Wei , Sai Mu Dalike Abaxi , Nawaz Mehmood , Luoquan Li , Fuyang Qu , Guangyao Cheng , Dehua Hu , Yi-Ping Ho , Scott Wu Yuan , Ho-Pui Ho

Polarized light microscopy provides high contrast to birefringent specimen and is widely used as a diagnostic tool in pathology. However, polarization microscopy systems typically operate by analyzing images collected from two or more light…

Deep learning (DL) models have been advancing automatic medical image analysis on various modalities, including echocardiography, by offering a comprehensive end-to-end training pipeline. This approach enables DL models to regress ejection…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Fadillah Adamsyah Maani , Numan Saeed , Aleksandr Matsun , Mohammad Yaqub

The accurate classification of white blood cells and related blood components is crucial for medical diagnoses. While traditional manual examinations and automated hematology analyzers have been widely used, they are often slow and prone to…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alexander Kim , Ryan Kim

Accurate classification of haematological cells is critical for diagnosing blood disorders, but presents significant challenges for machine automation owing to the complexity of cell morphology, heterogeneities of biological, pathological,…

Machine learning can extract information from neural recordings, e.g., surface EEG, ECoG and {\mu}ECoG, and therefore plays an important role in many research and clinical applications. Deep learning with artificial neural networks has…

Invasive coronary angiography (ICA) is the gold standard in Coronary Artery Disease (CAD) imaging. Detection of the end-diastolic frame (EDF) and, in general, cardiac phase detection on each temporal frame of a coronary angiography…

Adoption of deep learning in image steganalysis is still in its initial stage. In this paper we propose a generic hybrid deep-learning framework for JPEG steganalysis incorporating the domain knowledge behind rich steganalytic models. Our…

Multimedia · Computer Science 2018-01-24 Jishen Zeng , Shunquan Tan , Bin Li , Jiwu Huang

Autofluorescence lifetime images reveal unique characteristics of endogenous fluorescence in biological samples. Comprehensive understanding and clinical diagnosis rely on co-registration with the gold standard, histology images, which is…

Image and Video Processing · Electrical Eng. & Systems 2022-02-17 Qiang Wang , Susan Fernandes , Gareth O. S. Williams , Neil Finlayson , Ahsan R. Akram , Kevin Dhaliwal , James R. Hopgood , Marta Vallejo

Pulmonary Embolisms (PE) represent a leading cause of cardiovascular death. While medical imaging, through computed tomographic pulmonary angiography (CTPA), represents the gold standard for PE diagnosis, it is still susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-20 Florin Condrea , Saikiran Rapaka , Lucian Itu , Puneet Sharma , Jonathan Sperl , A Mohamed Ali , Marius Leordeanu
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