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Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Cardiovascular disease causes high rates of mortality worldwide. Coronary artery calcium (CAC) scoring is a powerful tool to stratify the risk of atherosclerotic cardiovascular disease. Current scoring practices require time-intensive…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Lachlan Nguyen , Aidan Cousins , Arcot Sowmya , Hugh Dixson , Sonit Singh

Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…

Cardiovascular disease (CVD) is a common and strong threat to human beings, featuring high prevalence, disability and mortality. The amount of coronary artery calcification (CAC) is an effective factor for CVD risk evaluation.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Jiechao Ma , Rongguo Zhang

Coronary artery calcium (CAC) is a significant marker of atherosclerosis and cardiovascular events. In this work we present a system for the automatic quantification of calcium score in ECG-triggered non-contrast enhanced cardiac computed…

Computer Vision and Pattern Recognition · Computer Science 2017-10-10 G. Santini , D. Della Latta , N. Martini , G. Valvano , A. Gori , A. Ripoli , C. L. Susini , L. Landini , D. Chiappino

Chest radiograph (or Chest X-Ray, CXR) is a popular medical imaging modality that is used by radiologists across the world to diagnose heart or lung conditions. Over the last decade, Convolutional Neural Networks (CNN), have seen success in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-24 Arsh Verma , Makarand Tapaswi

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

We propose a fully automated algorithm based on a deep learning framework enabling screening of a coronary computed tomography angiography (CCTA) examination for confident detection of the presence or absence of coronary artery…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Sema Candemir , Richard D. White , Mutlu Demirer , Vikash Gupta , Matthew T. Bigelow , Luciano M. Prevedello , Barbaros S. Erdal

Recent artificial intelligence (AI) algorithms have achieved radiologist-level performance on various medical classification tasks. However, only a few studies addressed the localization of abnormal findings from CXR scans, which is…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Hieu H. Pham , Ha Q. Nguyen , Hieu T. Nguyen , Linh T. Le , Lam Khanh

Analysing coronary artery plaque segments with respect to their functional significance and therefore their influence to patient management in a non-invasive setup is an important subject of current research. In this work we compare and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-16 Felix Denzinger , Michael Wels , Katharina Breininger , Anika Reidelshöfer , Joachim Eckert , Michael Sühling , Axel Schmermund , Andreas Maier

Chest X-Rays (CXRs) are widely used for diagnosing abnormalities in the heart and lung area. Automatically detecting these abnormalities with high accuracy could greatly enhance real world diagnosis processes. Lack of standard publicly…

Computer Vision and Pattern Recognition · Computer Science 2017-09-28 Mohammad Tariqul Islam , Md Abdul Aowal , Ahmed Tahseen Minhaz , Khalid Ashraf

X-ray coronary angiography (XCA) is the clinical reference standard for assessing coronary artery disease, yet quantitative analysis is limited by the difficulty of robust vessel segmentation in routine data. Low contrast, motion,…

Aims. To develop a deep-learning based system for recognition of subclinical atherosclerosis on a plain frontal chest x-ray. Methods and Results. A deep-learning algorithm to predict coronary artery calcium (CAC) score (the AI-CAC model)…

The chest X-Ray (CXR) is the one of the most common clinical exam used to diagnose thoracic diseases and abnormalities. The volume of CXR scans generated daily in hospitals is huge. Therefore, an automated diagnosis system able to save the…

Computer Vision and Pattern Recognition · Computer Science 2020-06-19 Shuai Zhang , Xiaoyan Xin , Yang Wang , Yachong Guo , Qiuqiao Hao , Xianfeng Yang , Jun Wang , Jian Zhang , Bing Zhang , Wei Wang

Coronary Artery Disease (CAD) diagnostic to be a major global cause of death, necessitating innovative solutions. Addressing the critical importance of early CAD detection and its impact on the mortality rate, we propose the potential of…

Signal Processing · Electrical Eng. & Systems 2024-06-26 Atitaya Phoemsuk , Vahid Abolghasemi

Coronary artery calcium (CAC) burden quantified in low-dose chest CT is a predictor of cardiovascular events. We propose an automatic method for CAC quantification, circumventing intermediate segmentation of CAC. The method determines a…

Computer Vision and Pattern Recognition · Computer Science 2017-12-11 Bob D. de Vos , Nikolas Lessmann , Pim A. de Jong , Max A. Viergever , Ivana Isgum

Early detection of coronary artery disease (CAD) is critical for reducing mortality and improving patient treatment planning. While angiographic image analysis from X-rays is a common and cost-effective method for identifying cardiac…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Alvee Hassan , Rusab Sarmun , Muhammad E. H. Chowdhury , M Murugappan , Abdulrahman Alqahtani , Balamurugan Balusamy , Sohaib Bassam Zoghoul

Coronary artery calcium (CAC) is highly predictive of cardiovascular events. While millions of chest CT scans are performed annually in the United States, CAC is not routinely quantified from scans done for non-cardiac purposes. A deep…

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