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It has been rightfully emphasized that the use of AI for clinical decision making could amplify health disparities. An algorithm may encode protected characteristics, and then use this information for making predictions due to undesirable…

Machine Learning · Computer Science 2022-07-22 Ben Glocker , Charles Jones , Melanie Bernhardt , Stefan Winzeck

Machine learning and artificial intelligence are fast-growing fields of research in which data is used to train algorithms, learn patterns, and make predictions. This approach helps to solve seemingly intricate problems with significant…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Shereiff Garrett , Abhinav Adhikari , Sarina Gautam , DaShawn Marquis Morris , Chandra Mani Adhikari

We systematically evaluate the performance of deep learning models in the presence of diseases not labeled for or present during training. First, we evaluate whether deep learning models trained on a subset of diseases (seen diseases) can…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Siyu Shi , Ishaan Malhi , Kevin Tran , Andrew Y. Ng , Pranav Rajpurkar

In this era of pandemic, the future of healthcare industry has never been more exciting. Artificial intelligence and machine learning (AI & ML) present opportunities to develop solutions that cater for very specific needs within the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Aravind Sasidharan Pillai

Chest X-rays (CXRs) are among the most commonly used medical image modalities. They are mostly used for screening, and an indication of disease typically results in subsequent tests. As this is mostly a screening test used to rule out chest…

Computer Vision and Pattern Recognition · Computer Science 2019-04-04 Ken C. L. Wong , Mehdi Moradi , Joy Wu , Tanveer Syeda-Mahmood

Advances in artificial intelligence (AI) have achieved expert-level performance in medical imaging applications. Notably, self-supervised vision-language foundation models can detect a broad spectrum of pathologies without relying on…

Computers and Society · Computer Science 2024-02-23 Yuzhe Yang , Yujia Liu , Xin Liu , Avanti Gulhane , Domenico Mastrodicasa , Wei Wu , Edward J Wang , Dushyant W Sahani , Shwetak Patel

Deep neural networks for image-based screening and computer-aided diagnosis have achieved expert-level performance on various medical imaging modalities, including chest radiographs. Recently, several works have indicated that these…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Ričards Marcinkevičs , Ece Ozkan , Julia E. Vogt

Detecting and classifying diseases using X-ray images is one of the more challenging core tasks in the medical and research world. Due to the recent high interest in radiological images and AI, early detection of diseases in X-ray images…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Liora Mayats-Alpay

There has been significant progress in implementing deep learning models in disease diagnosis using chest X- rays. Despite these advancements, inherent biases in these models can lead to disparities in prediction accuracy across protected…

Machine Learning · Computer Science 2024-03-28 Dana Moukheiber , Saurabh Mahindre , Lama Moukheiber , Mira Moukheiber , Mingchen Gao

The imperative for early detection of type 2 diabetes mellitus (T2DM) is challenged by its asymptomatic onset and dependence on suboptimal clinical diagnostic tests, contributing to its widespread global prevalence. While research into…

Machine Learning · Computer Science 2024-12-17 Sanjana Gundapaneni , Zhuo Zhi , Miguel Rodrigues

While deep learning has shown promise in improving the automated diagnosis of disease based on chest X-rays, deep networks may exhibit undesirable behavior related to shortcuts. This paper studies the case of spurious class skew in which…

Computer Vision and Pattern Recognition · Computer Science 2020-09-23 Sarah Jabbour , David Fouhey , Ella Kazerooni , Michael W. Sjoding , Jenna Wiens

Chest X-rays play a pivotal role in diagnosing respiratory diseases such as pneumonia, tuberculosis, and COVID-19, which are prevalent and present unique diagnostic challenges due to overlapping visual features and variability in image…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Yiming Lei , Michael Nguyen , Tzu Chia Liu , Hyounkyun Oh

We propose a novel deep neural network architecture for normalcy detection in chest X-ray images. This architecture treats the problem as fine-grained binary classification in which the normal cases are well-defined as a class while leaving…

Chest X-ray imaging remains the primary diagnostic tool for pulmonary and cardiac disorders worldwide, yet its accuracy is hampered by radiologist shortages and inter-observer variability. This study presents a systematic comparative…

Image and Video Processing · Electrical Eng. & Systems 2026-03-18 Ali M. Bahram , Saman Muhammad Omer , Hardi M. Mohammed

Deep learning models have shown promise in improving diagnostic accuracy from chest X-rays, but they also risk perpetuating healthcare disparities when performance varies across demographic groups. In this work, we present a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Clemence Mottez , Louisa Fay , Maya Varma , Sophie Ostmeier , Curtis Langlotz

Machine learning systems have received much attention recently for their ability to achieve expert-level performance on clinical tasks, particularly in medical imaging. Here, we examine the extent to which state-of-the-art deep learning…

Computer Vision and Pattern Recognition · Computer Science 2020-10-19 Laleh Seyyed-Kalantari , Guanxiong Liu , Matthew McDermott , Irene Y. Chen , Marzyeh Ghassemi

Deep neural networks for chest X-ray classification achieve strong average performance, yet often underperform for specific demographic subgroups, raising critical concerns about clinical safety and equity. Existing debiasing methods…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Darakshan Rashid , Raza Imam , Dwarikanath Mahapatra , Brejesh Lall

Deep neural networks excel in radiological image classification but frequently suffer from poor interpretability, limiting clinical acceptance. We present MedicalPatchNet, an inherently self-explainable architecture for chest X-ray…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Patrick Wienholt , Christiane Kuhl , Jakob Nikolas Kather , Sven Nebelung , Daniel Truhn

Automated diagnosis using deep neural networks in chest radiography can help radiologists detect life-threatening diseases. However, existing methods only provide predictions without accurate explanations, undermining the trustworthiness of…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Eunji Kim , Siwon Kim , Minji Seo , Sungroh Yoon

Recent research demonstrates that deep learning models are capable of precisely extracting bio-information (e.g. race, gender and age) from patients' Chest X-Rays (CXRs). In this paper, we further show that deep learning models are also…

Image and Video Processing · Electrical Eng. & Systems 2023-05-02 Hao Liang , Kevin Ni , Guha Balakrishnan
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