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The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…
In the past two years, large language model (LLM)-based chatbots, such as ChatGPT, have revolutionized various domains by enabling diverse task completion and question-answering capabilities. However, their application in scientific…
Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…
Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…
Recent advances in large language models (LLMs) have shown promising results in medical diagnosis, with some studies indicating superior performance compared to human physicians in specific scenarios. However, the diagnostic capabilities of…
Disease progression modeling (DPM) using longitudinal data is a challenging task in machine learning for healthcare that can provide clinicians with better tools for diagnosis and monitoring of disease. Existing DPM algorithms neglect…
In this study, we employ a transformer encoder model to characterize the significance of longitudinal patient data for forecasting the progression of Alzheimer's Disease (AD). Our model, Longitudinal Forecasting Model for Alzheimer's…
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…
Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…
The longitudinal modeling of neuroanatomical changes related to Alzheimer's disease (AD) is crucial for studying the progression of the disease. To this end, we introduce TransforMesh, a spatio-temporal network based on transformers that…
Dementia is a progressive neurodegenerative disorder with multiple etiologies, including Alzheimer's disease, Parkinson's disease, frontotemporal dementia, and vascular dementia. Its clinical and biological heterogeneity makes diagnosis and…
Diagnosing Alzheimer's disease (AD) involves a deliberate diagnostic process owing to its innate traits of irreversibility with subtle and gradual progression. These characteristics make AD biomarker identification from structural brain…
Mental disorders represent a critical global health challenge, and social media is increasingly viewed as a vital resource for real-time digital phenotyping and intervention. To leverage this data, large language models (LLMs) have been…
Graph plays a significant role in representing and analyzing complex relationships in real-world applications such as citation networks, social networks, and biological data. Recently, Large Language Models (LLMs), which have achieved…
Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…
Large language models (LLMs) show promise for health applications when combined with behavioral sensing data. Traditional approaches convert sensor data into text prompts, but this process is prone to errors, computationally expensive, and…
Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…
The ability to predict the future trajectory of a patient is a key step toward the development of therapeutics for complex diseases such as Alzheimer's disease (AD). However, most machine learning approaches developed for prediction of…
Graphs play an important role in representing complex relationships in various domains like social networks, knowledge graphs, and molecular discovery. With the advent of deep learning, Graph Neural Networks (GNNs) have emerged as a…
Forecasting the short-term spread of an ongoing disease outbreak is a formidable challenge due to the complexity of contributing factors, some of which can be characterized through interlinked, multi-modality variables such as…