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This study presents Latent Diffusion Autoencoder (LDAE), a novel encoder-decoder diffusion-based framework for efficient and meaningful unsupervised learning in medical imaging, focusing on Alzheimer disease (AD) using brain MR from the…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano , Henkjan Huisman

Medical image data is less accessible than in other domains due to privacy and regulatory constraints. In addition, labeling requires costly, time-intensive manual image annotation by clinical experts. To overcome these challenges,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Fangyijie Wang , Kevin Whelan , Félix Balado , Kathleen M. Curran , Guénolé Silvestre

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Human organs constantly undergo anatomical changes due to a complex mix of short-term (e.g., heartbeat) and long-term (e.g., aging) factors. Evidently, prior knowledge of these factors will be beneficial when modeling their future state,…

Computer Vision and Pattern Recognition · Computer Science 2023-06-19 Jee Seok Yoon , Chenghao Zhang , Heung-Il Suk , Jia Guo , Xiaoxiao Li

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Computer Vision and Pattern Recognition · Computer Science 2018-07-23 Guotai Wang , Wenqi Li , Maria A. Zuluaga , Rosalind Pratt , Premal A. Patel , Michael Aertsen , Tom Doel , Anna L. David , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Medical image artificial intelligence models often achieve strong performance in single-center or single-device settings, yet their effectiveness frequently deteriorates in real-world cross-center deployment due to domain shift, limiting…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jingsong Xia , Siqi Wang

Quality control (QC) of medical images is essential to ensure that downstream analyses such as segmentation can be performed successfully. Currently, QC is predominantly performed visually at significant time and operator cost. We aim to…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Richard Shaw , Carole H. Sudre , Sebastien Ourselin , M. Jorge Cardoso

The ongoing technological revolution in measurement systems enables the acquisition of high-resolution samples in fields such as engineering, biology, and medicine. However, these observations are often subject to errors from measurement…

Methodology · Statistics 2025-01-03 Mingyang Yi , Marcos Matabuena , Ruoyu Wang

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan

Video-driven neural face reenactment aims to synthesize realistic facial images that successfully preserve the identity and appearance of a source face, while transferring the target head pose and facial expressions. Existing GAN-based…

Computer Vision and Pattern Recognition · Computer Science 2025-03-26 Stella Bounareli , Christos Tzelepis , Vasileios Argyriou , Ioannis Patras , Georgios Tzimiropoulos

The proliferation of deep learning accelerators calls for efficient and cost-effective hardware design solutions, where parameterized modular hardware generator and electronic design automation (EDA) tools play crucial roles in improving…

Hardware Architecture · Computer Science 2025-04-01 Yi Ren , Chenhao Xue , Jiaxing Zhang , Chen Zhang , Qiang Xu , Yibo Lin , Lining Zhang , Guangyu Sun

Diffusion models have revolutionized image synthesis, setting new benchmarks in quality and creativity. However, their widespread adoption is hindered by the intensive computation required during the iterative denoising process.…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Huanpeng Chu , Wei Wu , Chengjie Zang , Kun Yuan

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng

Computational imaging is crucial in many disciplines from autonomous driving to life sciences. However, traditional model-driven and iterative methods consume large computational power and lack scalability for imaging. Deep learning (DL) is…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Weiru Fan , Xiaobin Tang , Yiyi Liao , Da-Wei Wang

The design of image and video quality assessment (QA) algorithms is extremely important to benchmark and calibrate user experience in modern visual systems. A major drawback of the state-of-the-art QA methods is their limited ability to…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Shankhanil Mitra , Diptanu De , Shika Rao , Rajiv Soundararajan

Cone-beam computed tomography (CBCT) is widely used for image-guided radiotherapy (IGRT). It provides real time visualization at low cost and dose. However, photon scattering and beam hindrance cause artifacts in CBCT. These include…

Medical Physics · Physics 2025-09-29 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

In many low-to-middle income (LMIC) countries, ultrasound is used for assessment of pleural effusion. Typically, the extent of the effusion is manually measured by a sonographer, leading to significant intra-/inter-observer variability. In…

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

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