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Prostate cancer is a commonly diagnosed cancerous disease among men world-wide. Even with modern technology such as multi-parametric magnetic resonance tomography and guided biopsies, the process for diagnosing prostate cancer remains time…

Image and Video Processing · Electrical Eng. & Systems 2024-04-17 Malte Rippa , Ruben Schulze , Marian Himstedt , Felice Burn

A novel deep learning architecture (XmasNet) based on convolutional neural networks was developed for the classification of prostate cancer lesions, using the 3D multiparametric MRI data provided by the PROSTATEx challenge. End-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-03-14 Saifeng Liu , Huaixiu Zheng , Yesu Feng , Wei Li

Prognostic task is of great importance as it closely related to the survival analysis of patients, the optimization of treatment plans and the allocation of resources. The existing prognostic models have shown promising results on specific…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Binyu Zhang , Shichao Li , Junpeng Jian , Zhu Meng , Limei Guo , Zhicheng Zhao

While meta-analyzing retrospective cancer patient cohorts, an investigation of differences in the expressions of target oncogenes across cancer subtypes is of substantial interest because the results may uncover novel tumorigenesis…

Methodology · Statistics 2023-07-03 Subharup Guha , David C. Christiani , S. V. Subramanian , Yi Li

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Prostate cancer is one of the most prevalent and deadly cancers among men, motivating the development of accurate and accessible imaging technologies for early detection. Ultrasound computed tomography (USCT) reconstructs quantitative…

Ovarian cancer remains one of the most lethal gynecological malignancies, largely due to late diagnosis and extensive heterogeneity across subtypes. Current diagnostic methods are limited in their ability to reveal underlying genomic…

Image and Video Processing · Electrical Eng. & Systems 2025-11-06 Gabriela Fernandes

Purpose: Demonstrating and assessing self-supervised machine learning fitting of the VERDICT (Vascular, Extracellular and Restricted DIffusion for Cytometry in Tumours) model for prostate. Methods: We derive a self-supervised neural network…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Snigdha Sen , Saurabh Singh , Hayley Pye , Caroline M. Moore , Hayley Whitaker , Shonit Punwani , David Atkinson , Eleftheria Panagiotaki , Paddy J. Slator

Artificial intelligence may assist healthcare systems in meeting increasing demand for pathology services while maintaining diagnostic quality and reducing turnaround time and costs. We aimed to investigate the performance of an…

This paper proposes a two-stage segmentation model, variable-input based uncertainty measures and an uncertainty-guided post-processing method for prostate segmentation on 3D magnetic resonance images (MRI). The two-stage model was based on…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Huitong Pan , Yushan Feng , Quan Chen , Craig Meyer , Xue Feng

This study investigates the application of quantum neural networks (QNNs) for propensity score estimation to address selection bias in comparing survival outcomes between laparoscopic and open surgical techniques in a cohort of 1177…

Quantum Physics · Physics 2025-06-26 Vojtěch Novák , Ivan Zelinka , Lenka Přibylová , Lubomír Martínek

High resolution micro-ultrasound has demonstrated promise in real-time prostate cancer detection, with deep learning becoming a prominent tool for learning complex tissue properties reflected on ultrasound. However, a significant roadblock…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Mahdi Gilany , Mohamed Harmanani , Paul Wilson , Minh Nguyen Nhat To , Amoon Jamzad , Fahimeh Fooladgar , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi

In Elmarakeby et al., "Biologically informed deep neural network for prostate cancer discovery", a feedforward neural network with biologically informed, sparse connections (P-NET) was presented to model the state of prostate cancer. We…

Machine Learning · Computer Science 2023-11-01 Christian Pedersen , Tiberiu Tesileanu , Tinghui Wu , Siavash Golkar , Miles Cranmer , Zijun Zhang , Shirley Ho

With the rapid development of computational pathology, many AI-assisted diagnostic tasks have emerged. Cellular nuclei segmentation can segment various types of cells for downstream analysis, but it relies on predefined categories and lacks…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Chunlin Zhong , Shuang Hao , Junhua Wu , Xiaona Chang , Jiwei Jiang , Xiu Nie , He Tang , Xiang Bai

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

Genomics · Quantitative Biology 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen

PURPOSE: The medical literature relevant to germline genetics is growing exponentially. Clinicians need tools monitoring and prioritizing the literature to understand the clinical implications of the pathogenic genetic variants. We…

Statistical inference on the cancer-site specificities of collective ultra-rare whole genome somatic mutations is an open problem. Traditional statistical methods cannot handle whole-genome mutation data due to their…

Methodology · Statistics 2023-01-02 Saptarshi Chakraborty , Zoe Guan , Colin B. Begg , Ronglai Shen

Biparametric magnetic resonance imaging (bpMRI) has demonstrated promising results in prostate cancer (PCa) detection using convolutional neural networks (CNNs). Recently, transformers have achieved competitive performance compared to CNNs…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Yuheng Li , Jacob Wynne , Jing Wang , Richard L. J. Qiu , Justin Roper , Shaoyan Pan , Ashesh B. Jani , Tian Liu , Pretesh R. Patel , Hui Mao , Xiaofeng Yang

Accurate segmentation of brain tumors is vital for diagnosis, surgical planning, and treatment monitoring. Deep learning has advanced on benchmarks, but two issues limit clinical use: no uncertainty estimates for errors and no segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-11-18 Andrew Zhou

Automated segmentation of BUS images is important for precise lesion delineation and tumor characterization, but is challenged by inherent artifacts and dataset inconsistencies. In this work, we evaluate the use of a modified Residual…