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Accurate prostate cancer diagnosis remains challenging. Even when using MRI, radiologists exhibit low specificity and significant inter-observer variability, leading to potential delays or inaccuracies in identifying clinically significant…

Prostate cancer being one of the frequently diagnosed malignancy in men, the rising demand for biopsies places a severe workload on pathologists. The grading procedure is tedious and subjective, motivating the development of automated…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Riddhasree Bhattacharyya , Pallabi Dutta , Sushmita Mitra

Prostate cancer is a highly prevalent cancer and ranks as the second leading cause of cancer-related deaths in men globally. Recently, the utilization of multi-modality transrectal ultrasound (TRUS) has gained significant traction as a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Hong Wu , Juan Fu , Hongsheng Ye , Yuming Zhong , Xuebin Zou , Jianhua Zhou , Yi Wang

Human cancers present a significant public health challenge and require the discovery of novel drugs through translational research. Transcriptomics profiling data that describes molecular activities in tumors and cancer cell lines are…

Prostate cancer is a leading cause of cancer-related deaths among men. The recent development of high frequency, micro-ultrasound imaging offers improved resolution compared to conventional ultrasound and potentially a better ability to…

Prostate cancer is a leading cause of mortality in men, yet interpretation of T2-weighted prostate MRI remains challenging due to subtle and heterogeneous lesions. We developed an interpretable framework for automatic cancer detection using…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Vahid Monfared , Mohammad Hadi Gharib , Ali Sabri , Maryam Shahali , Farid Rashidi , Amit Mehta , Reza Rawassizadeh

Interpreting traditional B-mode ultrasound images can be challenging due to image artifacts (e.g., shadowing, speckle), leading to low sensitivity and limited diagnostic accuracy. While Magnetic Resonance Imaging (MRI) has been proposed as…

Prostate cancer (Pca) continues to be a leading cause of cancer-related mortality in men, and the limitations in precision of traditional diagnostic methods such as the Digital Rectal Exam (DRE), Prostate-Specific Antigen (PSA) testing, and…

The diagnosis and monitoring of Castrate Resistant Prostate Cancer (CRPC) are crucial for cancer patients, but the current models (such as P-NET) have limitations in terms of parameter count, generalization, and cost. To address the issue,…

Machine Learning · Computer Science 2024-03-13 R. Li , J. Liu , X. L. Deng , X. Liu , J. C. Guo , W. Y. Wu , L. Yang

Prostate cancer, the second most prevalent male malignancy, requires advanced diagnostic tools. We propose an explainable AI system combining BERT (for textual clinical notes) and Random Forest (for numerical lab data) through a novel…

Prostate cancer (PCa) is a leading cause of cancer-related mortality in men, and accurate identification of clinically significant PCa (csPCa) is critical for timely intervention. Transrectal ultrasound (TRUS) is widely used for prostate…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Zetian Feng , Juan Fu , Xuebin Zou , Hongsheng Ye , Hong Wu , Jianhua Zhou , Yi Wang

Prostate cancer is a leading health concern among men, requiring accurate and accessible methods for early detection and risk stratification. Prostate volume (PV) is a key parameter in multivariate risk stratification for early prostate…

Image and Video Processing · Electrical Eng. & Systems 2025-02-13 Tiziano Natali , Liza M. Kurucz , Matteo Fusaglia , Laura S. Mertens , Theo J. M. Ruers , Pim J. van Leeuwen , Behdad Dashtbozorg

Deep models based on vision transformer (ViT) and convolutional neural network (CNN) have demonstrated remarkable performance on natural datasets. However, these models may not be similar in medical imaging, where abnormal regions cover…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Ahmad Chaddad , Yihang Wu , Xianrui Chen

While deep learning methods have shown great promise in improving the effectiveness of prostate cancer (PCa) diagnosis by detecting suspicious lesions from trans-rectal ultrasound (TRUS), they must overcome multiple simultaneous challenges.…

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

MOTIVATION: Detection of prostate cancer during transrectal ultrasound-guided biopsy is challenging. The highly heterogeneous appearance of cancer, presence of ultrasound artefacts, and noise all contribute to these difficulties. Recent…

Image and Video Processing · Electrical Eng. & Systems 2022-07-22 Mahdi Gilany , Paul Wilson , Amoon Jamzad , Fahimeh Fooladgar , Minh Nguyen Nhat To , Brian Wodlinger , Purang Abolmaesumi , Parvin Mousavi

Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

Machine Learning · Computer Science 2025-11-21 Chongmin Lee , Jihie Kim

In this paper, we present an uncertainty-aware INVASE to quantify predictive confidence of healthcare problem. By introducing learnable Gaussian distributions, we lever-age their variances to measure the degree of uncertainty. Based on the…

Machine Learning · Computer Science 2021-05-07 Jia-Xing Zhong , Hongbo Zhang

Multi-gene panel testing allows efficient detection of pathogenic variants in cancer susceptibility genes including moderate-risk genes such as ATM and PALB2. A growing number of studies examine the risk of breast cancer (BC) conferred by…

Manual Pap smear analysis for cervical cancer screening is limited by inter-observer variability, time constraints, and restricted expert availability. Although convolutional neural networks (CNNs) have automated cervical cell…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Nisreen Albzour , Sarah S. Lam
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