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A concentration difference of particles across a membrane perforated by pores will induce a diffusive flux. If the diffusing objects are of the same length scale as the the pores, diffusion may not be simple, objects can move into the pore…

Soft Condensed Matter · Physics 2015-05-18 Robert S. Shaw , Norman H. Packard

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

We consider the hydrodynamics of lipid bilayers containing transmembrane proteins of arbitrary shape. This biologically-motivated problem is relevant to the cell membrane, whose fluctuating dynamics play a key role in phenomena ranging from…

Soft Condensed Matter · Physics 2016-10-10 Andrew Callan-Jones , Marc Durand , Jean-Baptiste Fournier

Viscosity is a key property of cell membranes that controls mobility of embedded proteins and membrane remodeling. Measuring it is challenging because existing approaches involve complex experimental designs and/or models, and the…

Soft Condensed Matter · Physics 2023-07-19 Hammad A. Faizi , Rumiana Dimova , Petia M. Vlahovska

Membranes regulate transport in a wide variety of industrial and biological applications. The microscale geometry of the membrane can significantly affect overall transport through the membrane, but the precise nature of this multiscale…

Soft Condensed Matter · Physics 2026-02-02 Molly Brennan , Edwina F. Yeo , Philip Pearce , Mohit P. Dalwadi

We investigate pores in fluid membranes by molecular dynamics simulations of an amphiphile-solvent mixture, using a molecular coarse-grained model. The amphiphilic membranes self-assemble into a lamellar stack of amphiphilic bilayers…

Soft Condensed Matter · Physics 2009-11-11 Claire Loison , Michel Mareschal , Friederike Schmid

We develop a theoretical framework for understanding dynamic morphologies and stability of droplet interface bilayers (DIBs), accounting for lipid kinetics in the monolayers and bilayer, and droplet evaporation due to imbalance between…

Soft Condensed Matter · Physics 2018-06-13 Benjamin Guiselin , Jack O. Law , Buddhapriya Chakrabarti , Halim Kusumaatmaja

Many of the cell membrane vital functions are achieved by the self-organization of the proteins and biopolymers embedded in it. The protein dynamics are in part determined by its drag. A large number of these proteins can polymerize to form…

Fluid Dynamics · Physics 2023-09-13 Wenzheng Shi , Moslem Moradi , Ehssan Nazockdast

Active fluid droplets are a class of soft materials exhibiting autonomous motion sustained by an energy supply. Such systems have been shown to capture motility regimes typical of biological cells and are ideal candidates as building-block…

Soft Condensed Matter · Physics 2023-03-01 A. Tiribocchi , M. Durve , M. Lauricella , A. Montessori , D. Marenduzzo , S. Succi

Biomolecular condensates organize biochemical processes by spatially concentrating molecules while allowing for dynamic exchange with their surroundings. However, transport across their interface can be strongly attenuated, leading to…

Biological Physics · Physics 2026-03-27 Oihan Joyot , Zoé Ferrand , Fernando Muzzopappa , Pierre Weiss , Fabian Erdel

Plasma membranes appear as deformable systems wherein molecules are free to move and diffuse giving rise to condensed microdomains (composed of ordered lipids, transmembrane proteins and cholesterol) surrounded by disordered lipid…

Soft Condensed Matter · Physics 2024-09-25 Chiara Bernard , Angelo Rosario Carotenuto , Nicola Maria Pugno , Luca Deseri , Massimiliano Fraldi

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

Direct numerical simulations are used to elucidate the interplay of wettability and fluid viscosities on immiscible fluid displacements in a heterogeneous porous medium.We classify the flow regimes based using qualitative and quantitative…

Many natural and industrial systems involve particle-laden interfaces. Because interfacial particles prevent the coalescence and coarsening of drops, they hold promise for various applications requiring stable emulsions. Despite their…

Soft Condensed Matter · Physics 2026-04-08 Alexandros T. Oratis , Matteo Camagna , Timo J. J. M. van Overveld , Valeria Garbin

Membranes are ubiquitous in nature with primary functions that include adaptive filtering and selective transport of chemical and molecular species. Being critical to cellular functions, they are also fundamental in many areas of science…

Membrane organization is essential for cellular functions such as signal transduction and membrane trafficking. A major challenge is to understand the lateral heterogeneous structures in membranes and membrane fluidity in the presence of…

Soft Condensed Matter · Physics 2007-11-09 Chun-Lai Ren , Yu-qiang Ma

In the field of nanoconfined fluids, there are striking examples of deformation/transport coupling in which mechanical solicitation of the confining host and dynamics of the confined fluid impact each other. While this intriguing behavior…

Computational Physics · Physics 2024-04-01 Alexander Schlaich , Matthieu Vandamme , Marie Plazanet , Benoit Coasne

Motivated by recent experiments on biomimetic membranes exposed to several aqueous phases, we theoretically study the morphology of a membrane in contact with a liquid droplet formed via aqueous phase separation. We concentrate on membranes…

Soft Condensed Matter · Physics 2012-02-07 Halim Kusumaatmaja , Reinhard Lipowsky

Ionic transport in nano- to sub-nano-scale pores is highly dependent on translocation barriers and potential wells. These features in the free-energy landscape are primarily the result of ion dehydration and electrostatic interactions. For…

Mesoscale and Nanoscale Physics · Physics 2020-12-01 Subin Sahu , Michael Zwolak

The viscosity of lipid bilayer membranes plays an important role in determining the diffusion constant of embedded proteins and the dynamics of membrane deformations, yet it has historically proven very difficult to measure. Here we…

Soft Condensed Matter · Physics 2013-08-30 Aurelia R. Honerkamp-Smith , Francis G. Woodhouse , Vasily Kantsler , Raymond E. Goldstein
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