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Quadratic programming (QP) is a well-studied fundamental NP-hard optimization problem which optimizes a quadratic objective over a set of linear constraints. In this paper, we reformulate QPs as a mixed-integer linear problem (MILP). This…

Optimization and Control · Mathematics 2018-07-17 Wei Xia , Juan Vera , Luis F. Zuluaga

Mixed Integer Linear Programming (MILP) is a pillar of mathematical optimization that offers a powerful modeling language for a wide range of applications. During the past decades, enormous algorithmic progress has been made in solving…

Optimization and Control · Mathematics 2024-02-09 Lara Scavuzzo , Karen Aardal , Andrea Lodi , Neil Yorke-Smith

Despite the success of branch-and-cut methods for solving mixed integer bilevel linear optimization problems (MIBLPs) in practice, there are still gaps in both the theory and practice surrounding these methods. In the first part of this…

Optimization and Control · Mathematics 2025-10-06 Sahar Tahernejad , Ted K. Ralphs

Deep learning has been a prevalence in computational chemistry and widely implemented in molecule property predictions. Recently, self-supervised learning (SSL), especially contrastive learning (CL), gathers growing attention for the…

Machine Learning · Computer Science 2022-06-01 Yuyang Wang , Rishikesh Magar , Chen Liang , Amir Barati Farimani

Mixed-integer optimization is at the core of many online decision-making systems that demand frequent updates of decisions in real time. However, due to their combinatorial nature, mixed-integer linear programs (MILPs) can be difficult to…

Optimization and Control · Mathematics 2026-04-21 Shivi Dixit , Rishabh Gupta , Qi Zhang

Molecular Machine Learning (ML) bears promise for efficient molecule property prediction and drug discovery. However, labeled molecule data can be expensive and time-consuming to acquire. Due to the limited labeled data, it is a great…

Machine Learning · Computer Science 2022-04-01 Yuyang Wang , Jianren Wang , Zhonglin Cao , Amir Barati Farimani

A recent Graph Neural Network (GNN) approach for learning to branch has been shown to successfully reduce the running time of branch-and-bound algorithms for Mixed Integer Linear Programming (MILP). While the GNN relies on a GPU for…

Machine Learning · Computer Science 2020-10-26 Prateek Gupta , Maxime Gasse , Elias B. Khalil , M. Pawan Kumar , Andrea Lodi , Yoshua Bengio

We study a two-stage mixed-integer linear program (MILP) with more than 1 million binary variables in the second stage. We develop a two-level approach by constructing a semi-coarse model (coarsened with respect to variables) and a coarse…

Optimization and Control · Mathematics 2015-04-20 Fu Lin , Sven Leyffer , Todd Munson

Constraint Programming (CP) users need significant expertise in order to model their problems appropriately, notably to select propagators and search strategies. This puts the brakes on a broader uptake of CP. In this paper, we introduce…

Artificial Intelligence · Computer Science 2016-11-29 Thierry Petit

Mixed-integer linear programming (MILP) plays a crucial role in artificial intelligence, biochemistry, finance, cryptography, etc. Notwithstanding popular for decades, the researches of MILP solvers are still limited by the resource…

Quantum Physics · Physics 2022-04-12 Hao Wang , Yu Pan , Wei Cui

Many robotics problems, from robot motion planning to object manipulation, can be modeled as mixed-integer convex programs (MICPs). However, state-of-the-art algorithms are still unable to solve MICPs for control problems quickly enough for…

Robotics · Computer Science 2021-07-20 A. Cauligi , P. Culbertson , E. Schmerling , M. Schwager , B. Stellato , M. Pavone

We consider integer programming problems with bounded general-integer variables belonging to the general class of network flow problems. For those, we computationally investigate the effect on mixed-integer linear programming (MIP) solvers…

Optimization and Control · Mathematics 2026-04-09 Pierre Bonami , Sanjeeb Dash , Anton Derkach , Andrea Lodi

In this paper, we propose two exact distributed algorithms to solve mixed integer linear programming (MILP) problems with multiple agents where data privacy is important for the agents. A key challenge is that, because of the non-convex…

Optimization and Control · Mathematics 2022-05-03 Mohammad Javad Feizollahi

Biclustering techniques have been widely used to identify homogeneous subgroups within large data matrices, such as subsets of genes similarly expressed across subsets of patients. Mining a max-sum sub-matrix is a related but distinct…

Machine Learning · Statistics 2017-09-26 Vincent Branders , Pierre Schaus , Pierre Dupont

Autonomous systems must solve motion planning problems subject to increasingly complex, time-sensitive, and uncertain missions. These problems often involve high-level task specifications, such as temporal logic or chance constraints, which…

Systems and Control · Electrical Eng. & Systems 2026-04-28 Junyang Cai , Weimin Huang , Brendan Long , Matthew Cleaveland , Jyotirmoy V. Deshmukh , Lars Lindemann , Bistra Dilkina

Constraint ordering plays a critical role in the efficiency of Mixed-Integer Linear Programming (MILP) solvers, particularly for large-scale problems where poorly ordered constraints trigger increased LP iterations and suboptimal search…

Machine Learning · Computer Science 2025-04-08 Shuli Zeng , Mengjie Zhou , Sijia Zhang , Yixiang Hu , Feng Wu , Xiang-Yang Li

In this paper, we consider the network slicing (NS) problem which attempts to map multiple customized virtual network requests (also called services) to a common shared network infrastructure and manage network resources to meet diverse…

Information Theory · Computer Science 2025-07-03 Wei-Kun Chen , Ya-Feng Liu , Yu-Hong Dai , Zhi-Quan Luo

Cutting planes for mixed-integer linear programs (MILPs) are typically computed in rounds by iteratively solving optimization problems, the so-called separation. Instead, we reframe the problem of finding good cutting planes as a continuous…

Optimization and Control · Mathematics 2023-07-10 Didier Chételat , Andrea Lodi

Designing faster algorithms for solving Mixed-Integer Linear Programming (MILP) problems is highly desired across numerous practical domains, as a vast array of complex real-world challenges can be effectively modeled as MILP formulations.…

Artificial Intelligence · Computer Science 2026-01-23 Ruizhi Liu , Liming Xu , Xulin Huang , Jingyan Sui , Shizhe Ding , Boyang Xia , Chungong Yu , Dongbo Bu

We propose a supervised learning framework for computing solutions of multi-parametric Mixed Integer Linear Programs (MILPs) that arise in Model Predictive Control. Our approach also quantifies sub-optimality for the computed solutions.…

Systems and Control · Electrical Eng. & Systems 2023-03-24 Luigi Russo , Siddharth H. Nair , Luigi Glielmo , Francesco Borrelli