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We present a self-supervised, time-to-event (TTE) foundation model called MOTOR (Many Outcome Time Oriented Representations) which is pretrained on timestamped sequences of events in electronic health records (EHR) and health insurance…

Machine Learning · Computer Science 2023-12-06 Ethan Steinberg , Jason Fries , Yizhe Xu , Nigam Shah

Clinical machine learning models are increasingly trained using large scale, multimodal foundation paradigms, yet deployment environments often differ systematically from the data generating settings used during training. Such shifts arise…

Machine Learning · Computer Science 2026-03-10 Yuanyun Zhang , Shi Li

With the rise of medical foundation models and the growing availability of imaging data, scalable pretraining techniques offer a promising way to identify imaging biomarkers predictive of future disease risk. While current self-supervised…

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

This article studies the estimation of the causal effect of a time-varying treatment on time-to-an-event or on some other continuously distributed outcome. The paper applies to the situation where treatment is repeatedly adapted to…

Statistics Theory · Mathematics 2008-06-19 Judith J. Lok

Understanding and predicting microstructure evolution is fundamental to materials science, as it governs the resulting properties and performance of materials. Traditional simulation methods, such as phase-field models, offer high-fidelity…

Machine Learning · Computer Science 2026-02-24 Michael Trimboli , Mohammed Alsubaie , Sirani M. Perera , Ke-Gang Wang , Xianqi Li

When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel data structure, multiple treatments, censoring and unmeasured…

Methodology · Statistics 2022-02-18 Liangyuan Hu , Jiayi Ji , Ronald D. Ennis , Joseph W. Hogan

We study single-machine scheduling of jobs, each belonging to a job type that determines its duration distribution. We start by analyzing the scenario where the type characteristics are known and then move to two learning scenarios where…

Machine Learning · Computer Science 2023-06-02 Nadav Merlis , Hugo Richard , Flore Sentenac , Corentin Odic , Mathieu Molina , Vianney Perchet

Machine learning-aided clinical decision support has the potential to significantly improve patient care. However, existing efforts in this domain for principled quantification of uncertainty have largely been limited to applications of…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 L. Julian Lechuga Lopez , Tim G. J. Rudner , Farah E. Shamout

Surgical workflow anticipation can give predictions on what steps to conduct or what instruments to use next, which is an essential part of the computer-assisted intervention system for surgery, e.g. workflow reasoning in robotic surgery.…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Xiatian Zhang , Noura Al Moubayed , Hubert P. H. Shum

Clinical risk prediction using longitudinal medical data supports individualized care. Self-supervised foundation models have emerged as a promising approach for leveraging large-scale unlabeled healthcare records. In natural language…

Distributed cloud environments hosting data-intensive applications often experience slowdowns due to network congestion, asymmetric bandwidth, and inter-node data shuffling. These factors are typically not captured by traditional host-level…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-21 Sankalpa Timilsina , Susmit Shannigrahi

When optimizing problems with uncertain parameter values in a linear objective, decision-focused learning enables end-to-end learning of these values. We are interested in a stochastic scheduling problem, in which processing times are…

Machine Learning · Computer Science 2024-08-16 Kim van den Houten , David M. J. Tax , Esteban Freydell , Mathijs de Weerdt

Lung cancer patients frequently experience breakthrough pain episodes, with up to 91% requiring timely intervention. To enable proactive pain management, we propose a hybrid machine learning and large language model pipeline that predicts…

Artificial Intelligence · Computer Science 2026-05-22 Yipeng Zhuang , Yifeng Guo , Yuewen Li , Yuheng Wu , Philip Leung-Ho Yu , Tingting Song , Zhiyong Wang , Kunzhong Zhou , Weifang Wang , Li Zhuang

Traffic congestion caused by non-recurring incidents such as vehicle crashes and debris is a key issue for Traffic Management Centers (TMCs). Clearing incidents in a timely manner is essential for improving safety and reducing delays and…

Machine Learning · Computer Science 2023-04-25 Smrithi Ajit , Varsha R Mouli , Skylar Knickerbocker , Jonathan S. Wood

Time-to-event endpoints are central to evaluate treatment efficacy across many disease areas. Many trial protocols include interim analyses within group-sequential designs that control type I error via spending functions or boundary…

Methodology · Statistics 2026-01-19 Edoardo Ratti , Federico L. Perlino , Stefania Galimberti , Maria G. Valsecchi

We study the problem of scheduling jobs on fault-prone machines communicating via a shared channel, also known as multiple-access channel. We have $n$ arbitrary length jobs to be scheduled on $m$ identical machines, $f$ of which are prone…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-07-26 Marek Klonowski , Dariusz R. Kowalski , Jarosław Mirek , Prudence W. H. Wong

Clinical trials are a systematic endeavor to assess the safety and efficacy of new drugs or treatments. Conducting such trials typically demands significant financial investment and meticulous planning, highlighting the need for accurate…

Machine Learning · Computer Science 2025-11-03 Tien Huu Do , Antoine Masquelier , Nae Eoun Lee , Jonathan Crowther

Notable progress has been made in generalist medical large language models across various healthcare areas. However, large-scale modeling of in-hospital time series data - such as vital signs, lab results, and treatments in critical care -…

To develop intelligent speech assistants and integrate them seamlessly with intra-operative decision-support frameworks, accurate and efficient surgical phase recognition is a prerequisite. In this study, we propose a multimodal framework…

Audio and Speech Processing · Electrical Eng. & Systems 2024-06-24 Kubilay Can Demir , Belen Lojo Rodriguez , Tobias Weise , Andreas Maier , Seung Hee Yang
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