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Medical anomaly detection (AD) is crucial for early clinical intervention, yet it faces challenges due to limited access to high-quality medical imaging data, caused by privacy concerns and data silos. Few-shot learning has emerged as a…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Kaiyu Guo , Tan Pan , Chen Jiang , Zijian Wang , Brian C. Lovell , Limei Han , Yuan Cheng , Mahsa Baktashmotlagh

Diabetic Retinopathy (DR), a prevalent and severe complication of diabetes, affects millions of individuals globally, underscoring the need for accurate and timely diagnosis. Recent advancements in imaging technologies, such as…

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

In the modern world, one of the most severe eye infections brought on by diabetes is known as diabetic retinopathy, which will result in retinal damage, and, thus, lead to blindness. Diabetic retinopathy can be well treated with early…

Computer Vision and Pattern Recognition · Computer Science 2023-05-09 V. Banupriya , S. Anusuya

Reliable detection of retinal diseases from fundus images is challenged by the variability in imaging quality, subtle early-stage manifestations, and domain shift across datasets. In this study, we systematically evaluated a Vision…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Jan Benedikt Ruhland , Thorsten Papenbrock , Jan-Peter Sowa , Ali Canbay , Nicole Eter , Bernd Freisleben , Dominik Heider

Diabetic Retinopathy (DR) is a serious microvascular complication of diabetes, and one of the leading causes of vision loss worldwide. Although automated detection and grading, with Deep Learning (DL), can reduce the burden on…

Image and Video Processing · Electrical Eng. & Systems 2026-04-06 Shramana Dey , Zahir Khan , T. A. PramodKumar , B. Uma Shankar , Ashis K. Dhara , Ramachandran Rajalakshmi , Rajiv Raman , Sushmita Mitra

Unsupervised anomaly detection (UAD) in medical imaging is crucial for identifying pathological abnormalities without requiring extensive labeled data. However, existing diffusion-based UAD models rely solely on imaging features, limiting…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Harim Kim , Yuhan Wang , Minkyu Ahn , Heeyoul Choi , Yuyin Zhou , Charmgil Hong

Magnetic resonance diffusion tensor imaging (DTI) is a critical tool for neural disease diagnosis. However, long scan time greatly hinders the widespread clinical use of DTI. To accelerate image acquisition, a feature-enhanced joint…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Lang Zhang , Jinling He , Dong Liang , Hairong Zheng , Yanjie Zhu

Many developmental processes, such as plasticity and aging, or pathological processes such as neurological diseases are characterized by modulations of specific cellular types and their microstructures. Diffusion-weighted Magnetic Resonance…

Medical Physics · Physics 2019-03-26 Marco Palombo , Noam Shemesh , Itamar Ronen , Julien Valette

Diffusion MRI (dMRI) is essential for studying brain microstructure, but high-resolution imaging remains challenging due to the inherent trade-offs between acquisition time and signal-to-noise ratio (SNR). Conventional methods often…

Image and Video Processing · Electrical Eng. & Systems 2025-05-20 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Mengze Gao , Congyu Liao , Guang Yang , Kawin Setsompop

Discrete Wavelet Transform (DWT) has been widely explored to enhance the performance of image superresolution (SR). Despite some DWT-based methods improving SR by capturing fine-grained frequency signals, most existing approaches neglect…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Peng Du , Hui Li , Han Xu , Paul Barom Jeon , Dongwook Lee , Daehyun Ji , Ran Yang , Feng Zhu

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Diabetic retinopathy (DR) and age related macular degeneration (ARMD) are among the major causes of visual impairment worldwide. DR is mainly characterized by red spots, namely microaneurysms and bright lesions, specifically exudates…

Computer Vision and Pattern Recognition · Computer Science 2016-03-15 Ibrahim Sadek

Deep learning techniques are recently being used in fundus image analysis and diabetic retinopathy detection. Microaneurysms are an important indicator of diabetic retinopathy progression. We introduce a two-stage deep learning approach for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-25 Mhd Hasan Sarhan , Shadi Albarqouni , Mehmet Yigitsoy , Nassir Navab , Abouzar Eslami

Purpose: Microaneurysms (MAs) have distinct, oval-shaped, hyperreflective walls on structural OCT, and inconsistent flow signal in the lumen with OCT angiography (OCTA). Their relationship to regional macular edema in diabetic retinopathy…

Quantitative Methods · Quantitative Biology 2023-10-11 Min Gao , Tristan T. Hormel , Yukun Guo , Kotaro Tsuboi , Christina J. Flaxel , David Huang , Thomas S. Hwang , Yali Jia

Optical Coherence Tomography (OCT) is a novel and effective screening tool for ophthalmic examination. Since collecting OCT images is relatively more expensive than fundus photographs, existing methods use multi-modal learning to complement…

Image and Video Processing · Electrical Eng. & Systems 2023-08-02 Lehan Wang , Weihang Dai , Mei Jin , Chubin Ou , Xiaomeng Li

Supervised machine learning has enabled accurate pathology detection in brain MRI, but requires training data from diseased subjects that may not be readily available in some scenarios, for example, in the case of rare diseases.…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Ana Lawry Aguila , Peirong Liu , Oula Puonti , Juan Eugenio Iglesias

Objective: The study aims to address the challenge of aligning Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which is difficult due to their substantial differences in viewing range and the amorphous appearance of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kanggeon Lee , Su Jeong Song , Soochahn Lee , Kyoung Mu Lee

Diffusion models have demonstrated significant potential in producing high-quality images in medical image translation to aid disease diagnosis, localization, and treatment. Nevertheless, current diffusion models have limited success in…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yunxiang Li , Hua-Chieh Shao , Xiaoxue Qian , You Zhang

Anomaly detection in complex, high-dimensional data, such as UAV sensor readings, is essential for operational safety but challenging for existing methods due to their limited sensitivity, scalability, and inability to capture intricate…

Machine Learning · Computer Science 2025-10-28 Mingze Gong , Juan Du , Jianbang You