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The Quadratic Unconstrained Binary Optimization (QUBO) modeling and solution framework is a requirement for quantum and digital annealers. However optimality for QUBO problems of any practical size is extremely difficult to achieve. In…

Artificial Intelligence · Computer Science 2021-05-13 Amit Verma , Mark Lewis

Why rely on dense neural networks and then blindly sparsify them when prior knowledge about the problem structure is already available? Many inverse problems admit algorithm-unrolled networks that naturally encode physics and sparsity. In…

Machine Learning · Computer Science 2025-10-14 Arian Eamaz , Farhang Yeganegi , Mojtaba Soltanalian

With the advent of quantum computers, many quantum computing algorithms are being developed. Solving linear systems is one of the most fundamental problems in almost all science and engineering. The Harrow-Hassidim-Lloyd algorithm, a…

Quantum Physics · Physics 2022-01-25 Kyungtaek Jun

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems, which are often encountered in the industry (portfolio optimization, fleet optimization, charging stations, etc.). It was developed within the framework…

Optimization and Control · Mathematics 2026-04-15 Jérémie Messud , Yagnik Chatterjee

Hyperparameter optimization (HPO) is concerned with the automated search for the most appropriate hyperparameter configuration (HPC) of a parameterized machine learning algorithm. A state-of-the-art HPO method is Hyperband, which, however,…

Machine Learning · Computer Science 2023-02-07 Jasmin Brandt , Marcel Wever , Dimitrios Iliadis , Viktor Bengs , Eyke Hüllermeier

We implement a quantum generalization of a neural network on trapped-ion and IBM superconducting quantum computers to classify MNIST images, a common benchmark in computer vision. The network feedforward involves qubit rotations whose…

Quantum computing has emerged as a promising alternative for solving combinatorial optimization problems. The standard approach for encoding optimization problems on quantum processing units (QPUs) involves transforming them into their…

Emerging Technologies · Computer Science 2025-10-15 Meerzhan Kanatbekova , Vincenzo De Maio , Ivona Brandic

Quantum Approximate Optimization Algorithm (QAOA) can be used to solve quadratic unconstrained binary optimization (QUBO) problems. However, the size of the solvable problem is limited by the number of qubits. To leverage noisy…

Quantum Physics · Physics 2025-06-10 Wending Zhao , Gaoxiang Tang

We introduce a framework based on bilevel programming that unifies gradient-based hyperparameter optimization and meta-learning. We show that an approximate version of the bilevel problem can be solved by taking into explicit account the…

Machine Learning · Statistics 2018-07-04 Luca Franceschi , Paolo Frasconi , Saverio Salzo , Riccardo Grazzi , Massimilano Pontil

The main approach to hybrid quantum-classical neural networks (QNN) is employing quantum computing to build a neural network (NN) that has quantum features, which is then optimized classically. Here, we propose a different strategy: to use…

Quantum Physics · Physics 2025-04-22 Stefan-Alexandru Jura , Mihai Udrescu

The Quantum Approximate Optimization Algorithm (QAOA) requires considered optimization problems to be translated into a compatible format. A popular transformation step in this pipeline involves the quadratization of higher-order binary…

Quantum Physics · Physics 2025-11-26 Damian Rovara , Lukas Burgholzer , Robert Wille

The prospect of quantum solutions for complicated optimization problems is contingent on mapping the original problem onto a tractable quantum energy landscape, e.g. an Ising-type Hamiltonian. Subsequently, techniques like adiabatic…

Quantum Physics · Physics 2025-10-17 Sebastian Egginger , Kristina Kirova , Sonja Bruckner , Stefan Hillmich , Richard Kueng

The rapid expansion of biomolecular datasets presents significant challenges for computational biology. Quantum computing emerges as a promising solution to address these complexities. This study introduces a novel quantum framework for…

Chemical Physics · Physics 2025-07-02 Don Roosan , Rubayat Khan , Saif Nirzhor , Tiffany Khou , Fahmida Hai

This paper presents key enhancements to our previous work~\cite{naghmouchi2024mixed} on a hybrid Benders decomposition (HBD) framework for solving mixed integer linear programs (MILPs). In our approach, the master problem is reformulated as…

Quantum Physics · Physics 2026-01-23 Anna Joliot , M. Yassine Naghmouchi , Wesley Coelho

Bilevel optimization is a powerful tool for many machine learning problems, such as hyperparameter optimization and meta-learning. Estimating hypergradients (also known as implicit gradients) is crucial for developing gradient-based methods…

Optimization and Control · Mathematics 2025-05-06 Youran Dong , Junfeng Yang , Wei Yao , Jin Zhang

The Optimum-Path Forest is a graph-based framework for designing classifiers that exploit inter-sample connectivity. A particular variant constructs decision boundaries based on prototypes computed by a Minimum Spanning Tree (MST) over the…

Bilevel optimization (BLO) offers a principled framework for hierarchical decision-making and has been widely applied in machine learning tasks such as hyperparameter optimization and meta-learning. While existing BLO methods are mostly…

Optimization and Control · Mathematics 2025-10-20 Zhuo Chen , Xinjian Xu , Shihui Ying , Tieyong Zeng

Several combinatorial optimization problems can be solved with NISQ devices once that a corresponding quadratic unconstrained binary optimization (QUBO) form is derived. The aim of this work is to drastically reduce the variables needed for…

Quantum Physics · Physics 2026-02-25 Dario De Santis , Salvatore Tirone , Stefano Marmi , Vittorio Giovannetti

We introduce a novel Quadratic Unconstrained Binary Optimization (QUBO) formulation method for spanning tree problems. Instead of encoding the presence of edges in the tree individually, we opt to encode spanning trees as a permutation…

Data Structures and Algorithms · Computer Science 2022-09-13 Ivan Carvalho

Combinatorial optimization problems are typically formulated using Quadratic Unconstrained Binary Optimization (QUBO), where constraints are enforced through penalty terms that introduce auxiliary variables and rapidly increase Hamiltonian…

Quantum Physics · Physics 2026-02-10 Shashank Sanjay Bhat , Peiyong Wang , Joseph West , Udaya Parampalli