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Related papers: Fluence Map Prediction with Deep Learning: A Trans…

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Fluence map prediction is central to automated radiotherapy planning but remains an ill-posed inverse problem due to the complex relationship between volumetric anatomy and beam-intensity modulation. Convolutional methods in prior work…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Ujunwa Mgboh , Rafi Ibn Sultan , Joshua Kim , Kundan Thind , Dongxiao Zhu

Learning-based fluence map prediction offers a fast alternative to iterative inverse planning in intensity-modulated radiation therapy (IMRT), but its robustness under realistic distribution shifts remains unclear. We study a two-stage…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ujunwa Mgboh , Rafi Ibn Sultan , Joshua Kim , Kundan Thind , Dongxiao Zhu

Volumetric Modulated Arc Therapy (VMAT) revolutionizes cancer treatment by precisely delivering radiation while sparing healthy tissues. Fluence maps generation, crucial in VMAT planning, traditionally involves complex and iterative, and…

Image and Video Processing · Electrical Eng. & Systems 2025-02-06 Simon Arberet , Florin C. Ghesu , Riqiang Gao , Martin Kraus , Jonathan Sackett , Esa Kuusela , Ali Kamen

The field of Radiation Oncology is uniquely positioned to benefit from the use of artificial intelligence to fully automate the creation of radiation treatment plans for cancer therapy. This time-consuming and specialized task combines…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Kuancheng Wang , Hai Siong Tan , Rafe Mcbeth

We propose to develop deep learning models that can predict Pareto optimal dose distributions by using any given set of beam angles, along with patient anatomy, as input to train the deep neural networks. We implement and compare two deep…

Medical Physics · Physics 2021-01-27 Gyanendra Bohara , Azar Sadeghnejad Barkousaraie , Steve Jiang , Dan Nguyen

Volumetric Modulated Arc Therapy (VMAT) is a cornerstone of modern radiation therapy, enabling highly conformal tumor irradiation and healthy-tissue sparing. Yet, its planning solves inverse and nested optimization for multi-leaf…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Isabella Poles , Simon Arberet , Riqiang Gao , Martin Kraus , Marco D. Santambrogio , Florin C. Ghesu , Ali Kamen , Dorin Comaniciu

Purpose: Intensity-modulated proton therapy (IMPT) offers precise tumor coverage while sparing organs at risk (OARs) in head and neck (H&N) cancer. However, its sensitivity to anatomical changes requires frequent adaptation through online…

We propose a fast beam orientation selection method, based on deep neural networks (DNN), capable of developing a plan comparable to those by the state-of-the-art column generation method. The novelty of Our model lies in its supervised…

Medical Physics · Physics 2019-12-23 Azar Sadeghnejad Barkousaraie , Olalekan Ogunmolu , Steve Jiang , Dan Nguyen

In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…

Medical Physics · Physics 2021-02-03 Jiawei Fan , Lei Xing , Peng Dong , Jiazhou Wang , Weigang Hu , Yong Yang

In this first paper of a two-paper series, we present a method for optimizing the dynamic delivery of fluence maps in radiation therapy. For a given fluence map and a given delivery time, the optimization of the leaf trajectories of a…

Medical Physics · Physics 2016-08-10 David Craft , Marleen Balvert

Diffusion MRI is a non-invasive, in-vivo biomedical imaging method for mapping tissue microstructure. Applications include structural connectivity imaging of the human brain and detecting microstructural neural changes. However, acquiring…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Amir Sadikov , Xinlei Pan , Hannah Choi , Lanya T. Cai , Pratik Mukherjee

Image-guided mouse irradiation is essential to understand interventions involving radiation prior to human studies. Our objective is to employ Swin UNEt Transformers (Swin UNETR) to segment native micro-CT and contrast-enhanced micro-CT…

Medical Physics · Physics 2024-05-30 Lu Jiang , Di Xu , Qifan Xu , Arion Chatziioannou , Keisuke S. Iwamoto , Susanta Hui , Ke Sheng

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between…

Artificial Intelligence · Computer Science 2024-02-13 Zehao Dong , Yixin Chen , Hiram Gay , Yao Hao , Geoffrey D. Hugo , Pamela Samson , Tianyu Zhao

With the advancement of treatment modalities in radiation therapy for cancer patients, outcomes have improved, but at the cost of increased treatment plan complexity and planning time. The accurate prediction of dose distributions would…

Medical Physics · Physics 2018-12-03 Dan Nguyen , Troy Long , Xun Jia , Weiguo Lu , Xuejun Gu , Zohaib Iqbal , Steve Jiang

In this work, we present a novel convolutional neural net- work based method for perfusion map generation in dynamic suscepti- bility contrast-enhanced perfusion imaging. The proposed architecture is trained end-to-end and solely relies on…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Andreas Hess , Raphael Meier , Johannes Kaesmacher , Simon Jung , Fabien Scalzo , David Liebeskind , Roland Wiest , Richard McKinley

Conventional radiotherapy dose calculation algorithms are often computationally slow and non-differentiable, creating bottlenecks for online adaptive radiotherapy (ART) and limiting end-to-end automatic planning. Deep learning provides…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Medical Physics · Physics 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

Background: Accurate volumetric assessment of spontaneous subarachnoid hemorrhage (SAH) is a labor-intensive task performed with current manual and semiautomatic methods that might be relevant for its clinical and prognostic implications.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Sergio Garcia Garcia , Santiago Cepeda , Ignacio Arrese , Rosario Sarabia

Deep learning-based fluence map prediction(DL-FMP) method has been reported in the literature, which generated fluence maps for desired dose by deep neural network(DNN)-based inverse mapping. We hypothesized that DL-FMP is similar to…

Medical Physics · Physics 2021-05-03 Lin Ma , Mingli Chen , Xuejun Gu , Weiguo Lu
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