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We propose SAMed, a general solution for medical image segmentation. Different from the previous methods, SAMed is built upon the large-scale image segmentation model, Segment Anything Model (SAM), to explore the new research paradigm of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-18 Kaidong Zhang , Dong Liu

The Segment Anything Model (SAM) has recently gained popularity in the field of image segmentation due to its impressive capabilities in various segmentation tasks and its prompt-based interface. However, recent studies and individual…

Computer Vision and Pattern Recognition · Computer Science 2024-01-01 Junde Wu , Wei Ji , Yuanpei Liu , Huazhu Fu , Min Xu , Yanwu Xu , Yueming Jin

While the Segment Anything Model (SAM) excels in semantic segmentation for general-purpose images, its performance significantly deteriorates when applied to medical images, primarily attributable to insufficient representation of medical…

Computer Vision and Pattern Recognition · Computer Science 2023-11-07 Yiming Zhang , Tianang Leng , Kun Han , Xiaohui Xie

Accurate segmentation of cell nuclei in histopathology images is essential for numerous biomedical research and clinical applications. However, existing cell nucleus segmentation methods only consider a single dataset (i.e., primary…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Jiahe Qian , Yaoyu Fang , Jinkui Hao , Bo Zhou

The Segment Anything Model (SAM) has garnered significant attention for its versatile segmentation abilities and intuitive prompt-based interface. However, its application in medical imaging presents challenges, requiring either substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Zhiheng Cheng , Qingyue Wei , Hongru Zhu , Yan Wang , Liangqiong Qu , Wei Shao , Yuyin Zhou

The Segment Anything Model (SAM) has demonstrated remarkable capabilities of scaled-up segmentation models, enabling zero-shot generalization across a variety of domains. By leveraging large-scale foundational models as pre-trained models,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Weijia Feng , Lingting Zhu , Lequan Yu

Vision foundation models like the Segment Anything Model (SAM), pretrained on large-scale natural image datasets, often struggle in medical image segmentation due to a lack of domain-specific adaptation. In clinical practice, fine-tuning…

Computer Vision and Pattern Recognition · Computer Science 2025-11-03 Zelin Liu , Sicheng Dong , Bocheng Li , Yixuan Yang , Jiacheng Ruan , Chenxu Zhou , Suncheng Xiang

In medical image segmentation, heterogeneous privacy policies across institutions often make joint training on pooled datasets infeasible, motivating continual image segmentation-learning from data streams without catastrophic forgetting.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Jiayi Wang , Wei Dai , Haoyu Wang , Sihan Yang , Haixia Bi , Jian Sun

The Segment Anything Model (SAM) marks a significant advancement in segmentation models, offering robust zero-shot abilities and dynamic prompting. However, existing medical SAMs are not suitable for the multi-scale nature of whole-slide…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Hong Liu , Haosen Yang , Paul J. van Diest , Josien P. W. Pluim , Mitko Veta

With the emergence of the Segment Anything Model (SAM) as a foundational model for image segmentation, its application has been extensively studied across various domains, including the medical field. However, its potential in the context…

Computer Vision and Pattern Recognition · Computer Science 2023-10-17 SeungKyu Kim , Hyun-Jic Oh , Seonghui Min , Won-Ki Jeong

Semi-supervised learning has attracted much attention due to its less dependence on acquiring abundant annotations from experts compared to fully supervised methods, which is especially important for medical image segmentation which…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yichi Zhang , Jin Yang , Yuchen Liu , Yuan Cheng , Yuan Qi

The Segment Anything Model (SAM) has achieved remarkable successes in the realm of natural image segmentation, but its deployment in the medical imaging sphere has encountered challenges. Specifically, the model struggles with medical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Shreyank N Gowda , David A. Clifton

Medical image segmentation is a key task in the imaging workflow, influencing many image-based decisions. Traditional, fully-supervised segmentation models rely on large amounts of labeled training data, typically obtained through manual…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Tyler Ward , Meredith K. Owen , O'Kira Coleman , Brian Noehren , Abdullah-Al-Zubaer Imran

Leveraging the Segment Anything Model (SAM) for medical image segmentation remains challenging due to its limited adaptability across diverse medical domains. Although fine-tuned variants, such as MedSAM, improve performance in scenarios…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Jianghao Wu , Yicheng Wu , Yutong Xie , Wenjia Bai , You Zhang , Feilong Tang , Yulong Li , Imran Razzak , Daniel F Schmidt , Yasmeen George

The Segment Anything Model (SAM) has drawn significant attention from researchers who work on medical image segmentation because of its generalizability. However, researchers have found that SAM may have limited performance on medical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-28 Yihao Liu , Jiaming Zhang , Andres Diaz-Pinto , Haowei Li , Alejandro Martin-Gomez , Amir Kheradmand , Mehran Armand

The recent Segment Anything Model (SAM) represents a significant breakthrough in scaling segmentation models, delivering strong performance across various downstream applications in the RGB modality. However, directly applying SAM to…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Chenyang Zhu , Bin Xiao , Lin Shi , Shoukun Xu , Xu Zheng

Although the Segment Anything Model (SAM) is highly effective in natural image segmentation, it requires dependencies on prompts, which limits its applicability to medical imaging where manual prompts are often unavailable. Existing efforts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Mengmeng Zhang , Xingyuan Dai , Yicheng Sun , Jing Wang , Yueyang Yao , Xiaoyan Gong , Fuze Cong , Feiyue Wang , Yisheng Lv

Multimodal image fusion and semantic segmentation are critical for autonomous driving. Despite advancements, current models often struggle with segmenting densely packed elements due to a lack of comprehensive fusion features for guidance…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Daixun Li , Weiying Xie , Mingxiang Cao , Yunke Wang , Yusi Zhang , Leyuan Fang , Yunsong Li , Chang Xu

The Segment Anything Model (SAM) exhibits impressive capabilities in zero-shot segmentation for natural images. Recently, SAM has gained a great deal of attention for its applications in medical image segmentation. However, to our best…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Pengfei Gu , Zihan Zhao , Hongxiao Wang , Yaopeng Peng , Yizhe Zhang , Nishchal Sapkota , Chaoli Wang , Danny Z. Chen

The Segment Anything Model (SAM) is a promptable segmentation model recently introduced by Meta AI that has demonstrated its prowess across various fields beyond just image segmentation. SAM can accurately segment images across diverse…

Computer Vision and Pattern Recognition · Computer Science 2023-04-18 Junzhang Chen , Xiangzhi Bai
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