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The application of advanced generative artificial intelligence in education is often constrained by the lack of real-time adaptability, personalization, and reliability of the content. To address these challenges, we propose ExpertAgent -…

Artificial Intelligence · Computer Science 2025-10-10 Binrong Zhu , Guiran Liu , Nina Jiang

Creating end-to-end bioinformatics workflows requires diverse domain expertise, which poses challenges for both junior and senior researchers as it demands a deep understanding of both genomics concepts and computational techniques. While…

Artificial Intelligence (AI) agents capable of autonomous learning and independent decision-making hold great promise for addressing complex challenges across various critical infrastructure domains, including transportation, energy…

Multiagent Systems · Computer Science 2025-07-02 Hepeng Li , Yuhong Liu , Jun Yan , Jie Gao , Xiaoou Yang

As scientific research becomes increasingly complex, innovative tools are needed to manage vast data, facilitate interdisciplinary collaboration, and accelerate discovery. Large language models (LLMs) are now evolving into LLM-based…

Artificial Intelligence · Computer Science 2026-02-03 Shuo Ren , Can Xie , Pu Jian , Zhenjiang Ren , Chunlin Leng , Jiajun Zhang

In the rapidly evolving field of artificial intelligence, the ability to harness and integrate knowledge across various domains stands as a paramount challenge and opportunity. This study introduces a novel approach to cross-domain…

As data continues to grow in scale and complexity, preparing, transforming, and analyzing it remains labor-intensive, repetitive, and difficult to scale. Since data contains knowledge and AI learns knowledge from it, the alignment between…

Artificial Intelligence · Computer Science 2025-10-07 Yanjie Fu , Dongjie Wang , Wangyang Ying , Xinyuan Wang , Xiangliang Zhang , Huan Liu , Jian Pei

AI agents have seen widespread adoption in information retrieval for scientific research, giving rise to tools such as Deep Research. However, existing retrieval agents mainly rely on keyword- or embedding-based methods. While effective at…

Computational Engineering, Finance, and Science · Computer Science 2026-05-25 Chenyang Shao , Fengli Xu , Yong Li

Real-world mathematical modeling is inherently an experiential and collaborative endeavor. Domain experts rarely solve complex problems from scratch; instead, they draw upon analogies from historical cases and subject their hypotheses to…

Multiagent Systems · Computer Science 2026-04-03 Junhao Jia , Huangwei Chen , Ruiying Sun , Yanhui Song , Haishuai Wang , Jiajun Bu , Lei Wu

Reasoning is a fundamental cognitive process underlying inference, problem-solving, and decision-making. While large language models (LLMs) demonstrate strong reasoning capabilities in closed-world settings, they struggle in open-ended and…

Computational drug repurposing for rare diseases is especially challenging when no prior associations exist between drugs and target diseases. Therefore, knowledge graph completion and message-passing GNNs have little reliable signal to…

Artificial Intelligence · Computer Science 2025-10-17 Lang Qin , Zijian Gan , Xu Cao , Pengcheng Jiang , Yankai Jiang , Jiawei Han , Kaishun Wu , Jintai Chen

Language agents perform complex tasks by using tools to execute each step precisely. However, most existing agents are based on proprietary models or designed to target specific tasks, such as mathematics or multi-hop question answering. We…

Artificial Intelligence · Computer Science 2024-06-11 Joongwon Kim , Bhargavi Paranjape , Tushar Khot , Hannaneh Hajishirzi

Answering complex medical questions requires not only domain expertise and patient-specific information, but also structured and multi-perspective reasoning. Existing multi-agent approaches often rely on fixed roles or shallow interaction…

Artificial Intelligence · Computer Science 2026-03-04 Siqi Ma , Jiajie Huang , Fan Zhang , Yue Shen , Jinlin Wu , Guohui Fan , Zhu Zhang , Zelin Zang

This paper envisions a transformative paradigm in software engineering, where Artificial Intelligence, embodied in fully autonomous agents, becomes the primary driver of the core software development activities. We introduce a new class of…

Software Engineering · Computer Science 2025-12-03 Hoa Khanh Dam , Geeta Mahala , Rashina Hoda , Xi Zheng , Cristina Conati

In an era where single large language models have dominated the landscape of artificial intelligence for years, multi-agent systems arise as new protagonists in conversational task-solving. While previous studies have showcased their…

Computation and Language · Computer Science 2024-11-04 Jonas Becker

The history of science is punctuated by serendipitous discoveries, where unexpected observations, rather than targeted hypotheses, opened new fields of inquiry. While modern autonomous laboratories excel at accelerating hypothesis testing,…

Artificial Intelligence · Computer Science 2025-08-12 Lance Yao , Suman Samantray , Ayana Ghosh , Kevin Roccapriore , Libor Kovarik , Sarah Allec , Maxim Ziatdinov

We introduce Agentic Reasoning, a framework that enhances large language model (LLM) reasoning by integrating external tool-using agents. Agentic Reasoning dynamically leverages web search, code execution, and structured memory to address…

Artificial Intelligence · Computer Science 2025-07-16 Junde Wu , Jiayuan Zhu , Yuyuan Liu , Min Xu , Yueming Jin

Recent progress in Large Language Models (LLMs) has drawn attention to their potential for accelerating drug discovery. However, a central problem remains: translating theoretical ideas into robust implementations in the highly specialized…

Machine Learning · Computer Science 2025-03-06 Sizhe Liu , Yizhou Lu , Siyu Chen , Xiyang Hu , Jieyu Zhao , Yingzhou Lu , Yue Zhao

LLM agents can reason and use tools, but they often break down on long-horizon tasks due to unbounded context growth and accumulated errors. Common remedies such as context compression or retrieval-augmented prompting introduce trade-offs…

Artificial Intelligence · Computer Science 2026-01-07 Chenglin Yu , Yuchen Wang , Songmiao Wang , Hongxia Yang , Ming Li

Causal inference holds immense value in fields such as healthcare, economics, and social sciences. However, traditional causal analysis workflows impose significant technical barriers, requiring researchers to possess dual backgrounds in…

Artificial Intelligence · Computer Science 2026-02-13 Jiawei Zhu , Wei Chen , Ruichu Cai

The advancements of large language models (LLMs) have piqued growing interest in developing LLM-based language agents to automate scientific discovery end-to-end, which has sparked both excitement and skepticism about their true…

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