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State-transition models are essential across epidemiology and ecology, but statistical inference remains challenging owing to high-dimensional latent state spaces, temporal dependence, and intractable likelihood functions. Bayesian…

Computation · Statistics 2026-05-12 Alin Morariu , Jess Bridgen , Chris Jewell

The recently proposed generalized epidemic modeling framework (GEMF) \cite{sahneh2013generalized} lays the groundwork for systematically constructing a broad spectrum of stochastic spreading processes over complex networks. This article…

Physics and Society · Physics 2016-04-11 Faryad Darabi Sahneh , Aram Vajdi , Heman Shakeri , Futing Fan , Caterina Scoglio

Inferring how an epidemic will progress and what actions to take when presented with limited information is of critical importance for epidemiologists and health professionals. In real world settings, epidemiology data can be scarce or…

Computation · Statistics 2022-11-02 Georgios Efstathiadis

We propose the Gaussian-Linear Hidden Markov model (GLHMM), a generalisation of different types of HMMs commonly used in neuroscience. In short, the GLHMM is a general framework where linear regression is used to flexibly parameterise the…

Neurons and Cognition · Quantitative Biology 2024-10-02 Diego Vidaurre , Laura Masaracchia , Nick Y. Larsen , Lenno R. P. T Ruijters , Sonsoles Alonso , Christine Ahrends , Mark W. Woolrich

Propagation models are essential for modeling and simulating dynamic processes such as epidemics and information diffusion. However, existing tools struggle to scale to large-scale graphs that emerge across social networks, epidemic…

Social and Information Networks · Computer Science 2026-03-18 Chang Guo , Juyuan Zhang , Chang Su , Tianlong Fan , Linyuan Lü

Many probabilistic models introduce strong dependencies between variables using a latent multivariate Gaussian distribution or a Gaussian process. We present a new Markov chain Monte Carlo algorithm for performing inference in models with…

Computation · Statistics 2010-03-22 Iain Murray , Ryan Prescott Adams , David J. C. MacKay

Stochastic simulations are one of the cornerstones of the analysis of dynamical processes on complex networks, and are often the only accessible way to explore their behavior. The development of fast algorithms is paramount to allow…

Quantitative Methods · Quantitative Biology 2015-11-09 Christian L. Vestergaard , Mathieu Génois

StepMix is an open-source Python package for the pseudo-likelihood estimation (one-, two- and three-step approaches) of generalized finite mixture models (latent profile and latent class analysis) with external variables (covariates and…

Epidemic models are used to analyze the progression or outcome of an epidemic under different control policies like vaccinations, quarantines, lockdowns, use of face-masks, pharmaceutical interventions, etc. When these models accurately…

Quantitative Methods · Quantitative Biology 2022-04-19 Carlos Hernandez-Suarez , Osval Montsinos Lopez , Ramon Solano-Barajas

We initiate an open-source library for the efficient analysis of temporal graphs. We consider one of the standard models of dynamic networks in which each edge has a discrete timestamp and transition time. Recently there has been a massive…

Data Structures and Algorithms · Computer Science 2025-08-04 Lutz Oettershagen , Petra Mutzel

Mixed Integer Linear Programming (MILP) is a fundamental tool for modeling combinatorial optimization problems. Recently, a growing body of research has used machine learning to accelerate MILP solving. Despite the increasing popularity of…

Machine Learning · Computer Science 2024-10-29 Weimin Huang , Taoan Huang , Aaron M Ferber , Bistra Dilkina

Predicting the spread of processes across complex multi-layered networks has long challenged researchers due to the intricate interplay between network structure and propagation dynamics. Each layer of these networks possesses unique…

Social and Information Networks · Computer Science 2024-10-23 Mohammad Hossein Samaei , Faryad Darabi Sahneh , Caterina Scoglio

DeeProb-kit is a unified library written in Python consisting of a collection of deep probabilistic models (DPMs) that are tractable and exact representations for the modelled probability distributions. The availability of a representative…

Machine Learning · Computer Science 2022-12-09 Lorenzo Loconte , Gennaro Gala

Numerical simulation of continuous-time Markovian processes is an essential and widely applied tool in the investigation of epidemic spreading on complex networks. Due to the high heterogeneity of the connectivity structure through which…

Physics and Society · Physics 2017-07-26 Wesley Cota , Silvio C. Ferreira

Computational couplings of Markov chains provide a practical route to unbiased Monte Carlo estimation that can utilize parallel computation. However, these approaches depend crucially on chains meeting after a small number of transitions.…

Methodology · Statistics 2021-04-14 Brian L. Trippe , Tin D. Nguyen , Tamara Broderick

We present the R package SimInf which provides an efficient and very flexible framework to conduct data-driven epidemiological modeling in realistic large scale disease spread simulations. The framework integrates infection dynamics in…

Populations and Evolution · Quantitative Biology 2021-08-10 Stefan Widgren , Pavol Bauer , Robin Eriksson , Stefan Engblom

We developed a model and a software package for stochastic simulations of transmission of COVID-19 and other similar infectious diseases, that takes into account contact network structures and geographical distribution of population…

Populations and Evolution · Quantitative Biology 2021-05-19 Alexander Temerev , Liudmila Rozanova , Olivia Keiser , Janne Estill

We tackle limitations of ordinary differential equation-driven Susceptible-Infections-Removed (SIR) models and their extensions that have recently be employed for epidemic nowcasting and forecasting. In particular, we deal with challenges…

Computation · Statistics 2026-02-10 Angelos Alexopoulos , Paul Birrell , Daniela De Angelis

Stochastic processes on complex networks, where each node is in one of several compartments, and neighboring nodes interact with each other, can be used to describe a variety of real-world spreading phenomena. However, computational…

Social and Information Networks · Computer Science 2019-06-28 Gerrit Großmann , Luca Bortolussi

Nowadays the analysis of dynamics of and on networks represents a hot topic in the Social Network Analysis playground. To support students, teachers, developers and researchers in this work we introduce a novel framework, namely NDlib, an…

Social and Information Networks · Computer Science 2018-01-19 Giulio Rossetti , Letizia Milli , Salvatore Rinzivillo , Alina Sirbu , Fosca Giannotti , Dino Pedreschi
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