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Annotation ambiguity due to inherent data uncertainties such as blurred boundaries in medical scans and different observer expertise and preferences has become a major obstacle for training deep-learning based medical image segmentation…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yicheng Wu , Xiangde Luo , Zhe Xu , Xiaoqing Guo , Lie Ju , Zongyuan Ge , Wenjun Liao , Jianfei Cai

Widely adopted medical image segmentation methods, although efficient, are primarily deterministic and remain poorly amenable to natural language prompts. Thus, they lack the capability to estimate multiple proposals, human interaction, and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Yuan Lin , Murong Xu , Marc Hölle , Chinmay Prabhakar , Andreas Maier , Vasileios Belagiannis , Bjoern Menze , Suprosanna Shit

The domain discrepancy existed between medical images acquired in different situations renders a major hurdle in deploying pre-trained medical image segmentation models for clinical use. Since it is less possible to distribute training data…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Shishuai Hu , Zehui Liao , Yong Xia

To address prevalent issues in medical imaging, such as data acquisition challenges and label availability, transfer learning from natural to medical image domains serves as a viable strategy to produce reliable segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

Lesion segmentation is inherently influenced by imaging uncertainty, arising from ill-defined lesion boundaries and inter-observer variability in diagnosis. To address this challenge, previous works formulated the multi-rater medical image…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ke Liu , Shangde Gao , Yichao Fu , Shuaike Shen , Shangqi Gao , Chunhua Shen

Purpose: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targeted biopsies, cryoablation, and radiotherapy. However, subtle and variable tumour…

Image and Video Processing · Electrical Eng. & Systems 2026-02-23 Junqing Yang , Natasha Thorley , Ahmed Nadeem Abbasi , Shonit Punwani , Zion Tse , Yipeng Hu , Shaheer U. Saeed

Multi-rater medical image segmentation captures the inherent ambiguity of clinical interpretation, where diagnostic boundaries vary across experts and imaging devices. Existing approaches often reduce this diversity to consensus labels or…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Sanaz Karimijafarbigloo , Armin Khosravi , Alireza Kheyrkhah , Reza Azad , Mauricio Reyes , Dorit Merhof

The Medical Segment Anything Model (MedSAM) has shown remarkable performance in medical image segmentation, drawing significant attention in the field. However, its sensitivity to varying prompt types and locations poses challenges. This…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Nan Zhou , Ke Zou , Kai Ren , Mengting Luo , Linchao He , Meng Wang , Yidi Chen , Yi Zhang , Hu Chen , Huazhu Fu

Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Chengyin Li , Prashant Khanduri , Yao Qiang , Rafi Ibn Sultan , Indrin Chetty , Dongxiao Zhu

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Foundation models such as Segment Anything Model 3 (SAM3) enable flexible text-guided medical image segmentation, yet their predictions remain highly sensitive to prompt formulation. Even semantically equivalent descriptions can yield…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yonghuang Wu , Zhenyang Liang , Wenwen Zeng , Xuan Xie , Jinhua Yu

Dense annotations, such as segmentation masks, are expensive and time-consuming to obtain, especially for 3D medical images where expert voxel-wise labeling is required. Weakly supervised approaches aim to address this limitation, but often…

Computer Vision and Pattern Recognition · Computer Science 2026-04-21 Richard Petersen , Fredrik Kahl , Jennifer Alvén

The accurate segmentation of medical images is a crucial step in obtaining reliable morphological statistics. However, training a deep neural network for this task requires a large amount of labeled data to ensure high-accuracy results. To…

Image and Video Processing · Electrical Eng. & Systems 2023-07-04 Xianjun Han , Qianqian Chen , Zhaoyang Xie , Xuejun Li , Hongyu Yang

Deep learning offers transformative potential in medical imaging, yet its clinical adoption is frequently hampered by challenges such as data scarcity, distribution shifts, and the need for robust task generalization. Prompt-based…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Hao Yang , Xinlong Liang , Zhang Li , Yue Sun , Zheyu Hu , Xinghe Xie , Behdad Dashtbozorg , Jincheng Huang , Shiwei Zhu , Luyi Han , Jiong Zhang , Shanshan Wang , Ritse Mann , Qifeng Yu , Tao Tan

Recent advances in promptable segmentation, such as the Segment Anything Model (SAM), have enabled flexible, high-quality mask generation across a wide range of visual domains. However, SAM and similar models remain fundamentally…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Tyler Ward , Abdullah Imran

Neural networks pre-trained on a self-supervision scheme have become the standard when operating in data rich environments with scarce annotations. As such, fine-tuning a model to a downstream task in a parameter-efficient but effective…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Marc Fischer , Alexander Bartler , Bin Yang

Medical language-guided segmentation, integrating textual clinical reports as auxiliary guidance to enhance image segmentation, has demonstrated significant improvements over unimodal approaches. However, its inherent reliance on paired…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Shuchang Ye , Usman Naseem , Mingyuan Meng , Jinman Kim

The emergence of foundational models has significantly advanced segmentation approaches. However, challenges still remain in dense scenarios, where occlusions, scale variations, and clutter impede precise instance delineation. To address…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Muhammad Ibraheem Siddiqui , Muhammad Umer Sheikh , Hassan Abid , Muhammad Haris Khan

Existing approaches for the problem of ultrasound image segmentation, whether supervised or semi-supervised, are typically specialized for specific anatomical structures or tasks, limiting their practical utility in clinical settings. In…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Yaxiong Chen , Qicong Wang , Chunlei Li , Jingliang Hu , Yilei Shi , Shengwu Xiong , Xiao Xiang Zhu , Lichao Mou

Segmentation of the infected areas of the lung is essential for quantifying the severity of lung disease like pulmonary infections. Existing medical image segmentation methods are almost uni-modal methods based on image. However, these…

Image and Video Processing · Electrical Eng. & Systems 2023-07-11 Yi Zhong , Mengqiu Xu , Kongming Liang , Kaixin Chen , Ming Wu
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