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Related papers: Weighted Asymptotically Optimal Sequential Testing

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We develop asymptotic theory for weighted likelihood estimators (WLE) under two-phase stratified sampling without replacement. We also consider several variants of WLEs involving estimated weights and calibration. A set of empirical process…

Statistics Theory · Mathematics 2013-04-09 Takumi Saegusa , Jon A. Wellner

What can be considered an appropriate statistical method for the primary analysis of a randomized clinical trial (RCT) with a time-to-event endpoint when we anticipate non-proportional hazards owing to a delayed effect? This question has…

Methodology · Statistics 2023-04-18 José L. Jiménez , Isobel Barrott , Francesca Gasperoni , Dominic Magirr

Dedicated to the memory of Professor Tze Leung Lai, this paper introduces three multi-hypothesis sequential tests. These tests are derived from one-sided versions of the sequential probability ratio test and its modifications. They are…

Statistics Theory · Mathematics 2024-05-03 Alexander G. Tartakovsky

This paper introduces a quasi-likelihood ratio testing procedure for diffusion processes observed under nonsynchronous sampling schemes. High-frequency data, particularly in financial econometrics, are often recorded at irregular time…

Statistics Theory · Mathematics 2025-03-25 Teppei Ogihara , Futo Ueno

A key problem in structured output prediction is direct optimization of the task reward function that matters for test evaluation. This paper presents a simple and computationally efficient approach to incorporate task reward into a maximum…

Machine Learning · Computer Science 2017-01-05 Mohammad Norouzi , Samy Bengio , Zhifeng Chen , Navdeep Jaitly , Mike Schuster , Yonghui Wu , Dale Schuurmans

Non-proportional hazards (NPH) have been observed in confirmatory clinical trials with time to event outcomes. Under NPH, the hazard ratio does not stay constant over time and the log-rank test is no longer the most powerful test. The…

Methodology · Statistics 2022-09-26 Bharati Kumar , Jonathan W. Bartlett

Sequences with low aperiodic autocorrelation sidelobes are well known to have extensive applications in active sensing and communication systems. In this paper, we consider the problem of minimizing the weighted integrated sidelobe level…

Optimization and Control · Mathematics 2016-04-20 Junxiao Song , Prabhu Babu , Daniel P. Palomar

Recent years have seen tremendous advances in the theory and application of sequential experiments. While these experiments are not always designed with hypothesis testing in mind, researchers may still be interested in performing tests…

Econometrics · Economics 2023-06-29 Karun Adusumilli

Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs). Recently,…

Methodology · Statistics 2015-08-14 Xin Zhou , Nicole Mayer-Hamblett , Umer Khan , Michael R. Kosorok

We develop a nonparametric extension of the sequential generalized likelihood ratio (GLR) test and corresponding time-uniform confidence sequences for the mean of a univariate distribution. By utilizing a geometric interpretation of the GLR…

Statistics Theory · Mathematics 2021-05-17 Jaehyeok Shin , Aaditya Ramdas , Alessandro Rinaldo

In this paper we propose a class of weighted rank correlation coefficients extending the Spearman's rho. The proposed class constructed by giving suitable weights to the distance between two sets of ranks to place more emphasis on items…

Statistics Theory · Mathematics 2020-01-22 M. Sanatgar , A. Dolati , M. Amini

Heavy-tailed high-dimensional data are commonly encountered in various scientific fields and pose great challenges to modern statistical analysis. A natural procedure to address this problem is to use penalized quantile regression with…

Statistics Theory · Mathematics 2015-03-20 Jianqing Fan , Yingying Fan , Emre Barut

We consider the problem of sequential hypothesis testing by betting. For a general class of composite testing problems -- which include bounded mean testing, equal mean testing for bounded random tuples, and some key ingredients of…

Statistics Theory · Mathematics 2025-04-04 Ian Waudby-Smith , Ricardo Sandoval , Michael I. Jordan

Delayed separation of survival curves is a common occurrence in confirmatory studies in immuno-oncology. Many novel statistical methods that aim to efficiently capture potential long-term survival improvements have been proposed in recent…

Methodology · Statistics 2022-01-26 Dominic Magirr , José L. Jiménez

A family of variable stage size multistage tests of simple hypotheses is described, based on efficient multistage sampling procedures. Using a loss function that is a linear combination of sampling costs and error probabilities, these tests…

Statistics Theory · Mathematics 2009-09-29 Jay Bartroff

The widespread use of maximum Jeffreys'-prior penalized likelihood in binomial-response generalized linear models, and in logistic regression, in particular, are supported by the results of Kosmidis and Firth (2021, Biometrika), who show…

Methodology · Statistics 2024-06-10 Patrick Zietkiewicz , Ioannis Kosmidis

We present a new non-parametric statistic, called the weighed $\ell_2$ divergence, based on empirical distributions for sequential change detection. We start by constructing the weighed $\ell_2$ divergence as a fundamental building block…

Statistics Theory · Mathematics 2021-02-25 Liyan Xie , Yao Xie

The role played by the composite analogue of the log likelihood ratio in hypothesis testing and in setting confidence regions is not as prominent as it is in the canonical likelihood setting, since its asymptotic distribution depends on the…

Methodology · Statistics 2013-01-30 Nicola Lunardon

A simple and common type of medical research involves the comparison of one treatment against another. The logical aim should be both to establish which treatment is superior and the strength of evidence supporting this conclusion, a task…

Methodology · Statistics 2022-12-08 Nicholas Adams

Recently Liu and Wang derived the likelihood ratio test (LRT) statistic and its asymptotic distribution for testing equality of two multinomial distributions vs. the alternative that the second distribution is larger in terms of increasing…

Statistics Theory · Mathematics 2007-06-13 Arthur Cohen , John Kolassa , Harold Sackrowitz