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Cervical cancer is one of the most deadly and common diseases among women worldwide. It is completely curable if diagnosed in an early stage, but the tedious and costly detection procedure makes it unviable to conduct population-wise…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Hritam Basak , Rohit Kundu , Sukanta Chakraborty , Nibaran Das

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Time series classification is an important analytical task across diverse domains. However, its practical application is often hindered by the scarcity of labeled data and the requirement for substantial computational resources. To address…

Machine Learning · Computer Science 2026-04-29 Xuanhao Yang , Bing Xue , Mengjie Zhang

Histopathology Whole-Slide Images (WSIs) provide an important tool to assess cancer prognosis in computational pathology (CPATH). While existing survival analysis (SA) approaches have made exciting progress, they are generally limited to…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Pei Liu , Luping Ji , Jiaxiang Gou , Bo Fu , Mao Ye

Vision Transformers (ViTs) have gained rapid adoption in computational pathology for their ability to model long-range dependencies through self-attention, addressing the limitations of convolutional neural networks that excel at local…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Fuyao Chen , Yuexi Du , Elèonore V. Lieffrig , Nicha C. Dvornek , John A. Onofrey

Deep learning has significantly advanced image edge detection (ED), primarily through improved feature extraction. However, most existing ED models apply uniform feature fusion across all pixels, ignoring critical differences between…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Hao Shu

Application of deep learning on histopathological whole slide images (WSIs) holds promise of improving diagnostic efficiency and reproducibility but is largely dependent on the ability to write computer code or purchase commercial…

Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Tarun G , Naman Malpani , Gugan Thoppe , Sridharan Devarajan

Recent advances in artificial intelligence (AI), in particular self-supervised learning of foundation models (FMs), are revolutionizing medical imaging and computational pathology (CPath). A constant challenge in the analysis of digital…

Recently, Pareto Set Learning (PSL) has been proposed for learning the entire Pareto set using a neural network. PSL employs preference vectors to scalarize multiple objectives, facilitating the learning of mappings from preference vectors…

Neural and Evolutionary Computing · Computer Science 2024-04-15 Rongguang Ye , Longcan Chen , Jinyuan Zhang , Hisao Ishibuchi

Deep learning models tend to memorize training data, which hurts their ability to generalize to under-represented classes. We empirically study a convolutional neural network's internal representation of imbalanced image data and measure…

Machine Learning · Computer Science 2022-10-19 Damien Dablain , Colin Bellinger , Bartosz Krawczyk , Nitesh Chawla

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

Image and Video Processing · Electrical Eng. & Systems 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

We propose EVOlutionary Selector (EVOS), an efficient training paradigm for accelerating Implicit Neural Representation (INR). Unlike conventional INR training that feeds all samples through the neural network in each iteration, our…

Computer Vision and Pattern Recognition · Computer Science 2025-04-07 Weixiang Zhang , Shuzhao Xie , Chengwei Ren , Siyi Xie , Chen Tang , Shijia Ge , Mingzi Wang , Zhi Wang

Tumor segmentation stands as a pivotal task in cancer diagnosis. Given the immense dimensions of whole slide images (WSI) in histology, deep learning approaches for WSI classification mainly operate at patch-wise or superpixel-wise level.…

Computer Vision and Pattern Recognition · Computer Science 2024-02-22 Huaqian Wu , Clara Brémond-Martin , Kévin Bouaou , Cédric Clouchoux

Recent breakthroughs in object detection and image classification using Convolutional Neural Networks (CNNs) are revolutionizing the state of the art in medical imaging, and microscopy in particular presents abundant opportunities for…

Image and Video Processing · Electrical Eng. & Systems 2020-07-07 Rui Aguiar , Jon Braatz

The emergence of foundation models in computational pathology has transformed histopathological image analysis, with whole slide imaging (WSI) diagnosis being a core application. Traditionally, weakly supervised fine-tuning via multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Jiawen Li , Jiali Hu , Qiehe Sun , Renao Yan , Minxi Ouyang , Tian Guan , Anjia Han , Chao He , Yonghong He

Random splitting of datasets in image segmentation often leads to unrepresentative test sets, resulting in biased evaluations and poor model generalization. While stratified sampling has proven effective for addressing label distribution…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Naga Venkata Sai Jitin Jami , Thomas Altstidl , Jonas Mueller , Jindong Li , Dario Zanca , Bjoern Eskofier , Heike Leutheuser

Representation learning from Gigapixel Whole Slide Images (WSI) poses a significant challenge in computational pathology due to the complicated nature of tissue structures and the scarcity of labeled data. Multi-instance learning methods…

Image and Video Processing · Electrical Eng. & Systems 2024-05-28 Ali Nasiri-Sarvi , Vincent Quoc-Huy Trinh , Hassan Rivaz , Mahdi S. Hosseini

While classical scaling, just like principal component analysis, is parameter-free, other methods for embedding multivariate data require the selection of one or several tuning parameters. This tuning can be difficult due to the…

Methodology · Statistics 2023-10-19 Ery Arias-Castro , Phong Alain Chau

Multiple instance learning (MIL) has become a preferred method for gigapixel whole slide image (WSI) classification without requiring patch-level annotations. Current MIL research primarily relies on embedding-based approaches, which…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Bryan Wong , Sungrae Hong , Mun Yong Yi