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Related papers: Higher-Order Interactions in Brain Connectomics: I…

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The standard approach to modeling the human brain as a complex system is with a network, where the basic unit of interaction is a pairwise link between two brain regions. While powerful, this approach is limited by the inability to assess…

Neurons and Cognition · Quantitative Biology 2023-01-16 Thomas F Varley , Maria Pope , Maria Grazia Puxeddu , Joshua Faskowitz , Olaf Sporns

Understanding the human brain remains the Holy Grail in biomedical science, and arguably in all of the sciences. Our brains represent the most complex systems in the world (and some contend the universe) comprising nearly one hundred…

Quantitative Methods · Quantitative Biology 2016-02-03 Sean L. Simpson , Paul J. Laurienti

In this work, we developed new mathematical methods for analyzing network topology and applied these methods to the analysis of brain networks. More specifically, we rigorously developed quantitative methods based on complexes constructed…

Neurons and Cognition · Quantitative Biology 2026-04-28 Heitor Baldo

Higher-order interactions that nonlinearly couple more than two nodes are important in many networked systems, and their effects on collective dynamics are increasingly being studied. Here we provide an overview of this rapidly growing…

Adaptation and Self-Organizing Systems · Physics 2026-03-23 Federico Battiston , Christian Bick , Maxime Lucas , Ana P. Millán , Per Sebastian Skardal , Yuanzhao Zhang

Interacting systems are ubiquitous in nature and engineering, ranging from particle dynamics in physics to functionally connected brain regions. These interacting systems can be modeled by graphs where edges correspond to the interactions…

Machine Learning · Computer Science 2024-01-25 Zhichao Han , Olga Fink , David S. Kammer

Understanding the complexity of biological neural networks like the human brain is one of the scientific challenges of our century. The organization of the brain can be described at different levels, ranging from small neural networks to…

Neurons and Cognition · Quantitative Biology 2018-05-23 Stefano De Blasi

Deep learning has seen a movement away from representing examples with a monolithic hidden state towards a richly structured state. For example, Transformers segment by position, and object-centric architectures decompose images into…

Graph embedding is a powerful method to represent graph neurological data (e.g., brain connectomes) in a low dimensional space for brain connectivity mapping, prediction and classification. However, existing embedding algorithms have two…

Computer Vision and Pattern Recognition · Computer Science 2020-09-25 Alin Banka , Inis Buzi , Islem Rekik

Many real-world domains can be expressed as graphs and, more generally, as multi-relational knowledge graphs. Though reasoning and learning with knowledge graphs has traditionally been addressed by symbolic approaches, recent methods in…

Artificial Intelligence · Computer Science 2020-03-25 Sebastijan Dumancic , Alberto Garcia-Duran , Mathias Niepert

Networks in nature have complex interactions among agents. One significant phenomenon induced by interactions is synchronization of coupled agents, and the interactive network topology can be tuned to optimize synchronization. The previous…

Physics and Society · Physics 2021-08-26 Ying Tang , Dinghua Shi , Linyuan Lü

Network models describe the brain as sets of nodes and edges that represent its distributed organization. So far, most discoveries in network neuroscience have prioritized insights that highlight distinct groupings and specialized…

Neurons and Cognition · Quantitative Biology 2021-05-18 Joshua Faskowitz , Richard F. Betzel , Olaf Sporns

Understanding and predicting mobility dynamics in transportation networks is critical for infrastructure planning, resilience analysis, and traffic management. Traditional graph-based models typically assume memoryless movement, limiting…

Social and Information Networks · Computer Science 2025-07-11 Chen Zhang , Jürgen Hackl

Recent studies have shown that novel collective behaviors emerge in complex systems due to the presence of higher-order interactions. However, how the collective behavior of a system is influenced by the microscopic organization of its…

Physics and Society · Physics 2025-07-01 Federico Malizia , Santiago Lamata-Otín , Mattia Frasca , Vito Latora , Jesús Gómez-Gardeñes

Humans are adept at uncovering abstract associations in the world around them, yet the underlying mechanisms remain poorly understood. Intuitively, learning the higher-order structure of statistical relationships should involve complex…

Neurons and Cognition · Quantitative Biology 2020-03-26 Christopher W. Lynn , Ari E. Kahn , Nathaniel Nyema , Danielle S. Bassett

Identifying central entities and interactions is a fundamental problem in network science. While well-studied for graphs (pairwise relations), many biological and social systems exhibit higher-order interactions best modeled by hypergraphs.…

Physics and Society · Physics 2025-12-02 Jaewan Chun , Fanchen Bu , Yeongho Kim , Atsushi Miyauchi , Francesco Bonchi , Kijung Shin

Understanding cooperation in social dilemmas requires models that capture the complexity of real-world interactions. While network frameworks have provided valuable insights to model the evolution of cooperation, they are unable to encode…

Physics and Society · Physics 2025-07-15 Onkar Sadekar , Andrea Civilini , Vito Latora , Federico Battiston

Higher-order interactions underlie complex phenomena in systems such as biological and artificial neural networks, but their study is challenging due to the scarcity of tractable models. By leveraging a generalisation of the maximum entropy…

Disordered Systems and Neural Networks · Physics 2025-12-10 Miguel Aguilera , Pablo A. Morales , Fernando E. Rosas , Hideaki Shimazaki

Resting-state functional magnetic resonance imaging (fMRI) has emerged as a cornerstone for psychiatric diagnosis, yet most approaches rely on pairwise brain cortical or sub-cortical connectivities that overlooks higher-order interactions…

Machine Learning · Computer Science 2026-04-21 Kunyu Zhang , Qiang Li , Vince D. Calhoun , Shujian Yu

Recent empirical evidence has shown that in many real-world systems, successfully represented as networks, interactions are not limited to dyads, but often involve three or more agents at a time. These data are better described by…

Physics and Society · Physics 2021-04-01 Federico Musciotto , Federico Battiston , Rosario N. Mantegna

The proliferation of deep neural networks in various domains has seen an increased need for interpretability of these models. Preliminary work done along this line and papers that surveyed such, are focused on high-level representation…

Computation and Language · Computer Science 2022-08-17 Hassan Sajjad , Nadir Durrani , Fahim Dalvi