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Transmission dynamics of infectious diseases are often studied using compartmental mathematical models, which are commonly represented as systems of autonomous ordinary differential equations. A key step in the analysis of such models is to…

Populations and Evolution · Quantitative Biology 2025-12-15 David J. D. Earn , C. Connell McCluskey

The COVID-19 pandemic highlighted the need to improve the modeling, estimation, and prediction of how infectious diseases spread. SEIR-like models have been particularly successful in providing accurate short-term predictions. This study…

Populations and Evolution · Quantitative Biology 2024-12-31 Jorge P. Zubelli , Jennifer Loria , Vinicius V. L. Albani

Raw data on the cumulative number of deaths at a country level generally indicate a spatially variable distribution of the incidence of COVID-19 disease. An important issue is to determine whether this spatial pattern is a consequence of…

Populations and Evolution · Quantitative Biology 2020-07-21 Lionel Roques , Olivier Bonnefon , Virgile Baudrot , Samuel Soubeyrand , Henri Berestycki

This paper deals with a new epidemiological model of SIRS with stochastic perturbations. The primary objective is to establish the existence of a unique non-negative nonlocal solution. Using the basic reproduction number $\mathscr{R}_0$…

Dynamical Systems · Mathematics 2025-03-10 Achraf Zinihi , Moulay Rchid Sidi Ammi , Matthias Ehrhardt

This work proposes and analyzes a family of spatially inhomogeneous epidemic models. This is our first effort to use stochastic partial differential equations (SPDEs) to model epidemic dynamics with spatial variations and environmental…

Dynamical Systems · Mathematics 2020-01-01 Dang H Nguyen , Nhu N Nguyen , George Yin

We study the influence of heterogeneous mobility patterns in a population on the SIS epidemic model. In particular, we consider a patchy environment in which each patch comprises individuals belonging the different classes, e.g.,…

Systems and Control · Electrical Eng. & Systems 2020-03-31 Vishal Abhishek , Vaibhav Srivastava

The outbreak of COVID-19 in 2020 has led to a surge in interest in the mathematical modeling of infectious diseases. Such models are usually defined as compartmental models, in which the population under study is divided into compartments…

Populations and Evolution · Quantitative Biology 2021-02-16 Malú Grave , Alex Viguerie , Gabriel F. Barros , Alessandro Reali , Alvaro L. G. A. Coutinho

In this paper, we analyze dynamic switching networks, wherein the networks switch arbitrarily among a set of topologies. For this class of dynamic networks, we derive an epidemic threshold, considering the SIS epidemic model. First, an…

Social and Information Networks · Computer Science 2015-08-03 Mohammad Reza Sanatkar , Warren N. White , Balasubramaniam Natarajan , Caterina Scoglio , Karren A. Garrett

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

This paper continues to study the monostable cooperative system with nonlocal diffusion and free boundary, which has recently been discussed by [Du and Ni, 2020, arXiv:2010.01244]. We here aim at the four aspects: the first is to give more…

Analysis of PDEs · Mathematics 2021-11-12 Lei Li , Xueping Li , Mingxin Wang

We study the spread of disease in an SIS model. The model considered is a time-varying, switched model, in which the parameters of the SIS model are subject to abrupt change. We show that the joint spectral radius can be used as a threshold…

Dynamical Systems · Mathematics 2014-04-21 Mustapha Ait Rami , Vahid S. Bokharaie , Oliver Mason , Fabian R. Wirth

The conceptual difference between equilibrium and non-equilibrium steady state (NESS) is well established in physics and chemistry. This distinction, however, is not widely appreciated in dynamical descriptions of biological populations in…

Populations and Evolution · Quantitative Biology 2012-02-23 Jia-Zeng Wang , Min Qian , Hong Qian

We consider a parabolic non-local free boundary problem that has been derived as a limit of a bulk-surface reaction-diffusion system which models cell polarization. The authors have justified the well-posedness of this problem and have…

Analysis of PDEs · Mathematics 2023-04-24 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

Medical statistics reveal a significant dependence of hospitalized dengue patient on the patient's age. To incorporate an age-dependence into a mathematical model, we extend the classical ODE system of disease dynamics to a PDE system. The…

Populations and Evolution · Quantitative Biology 2019-08-27 N. C. Ganegoda , T. Götz , K. P. Wijaya

A novel predictive modeling framework for the spread of infectious diseases using high dimensional partial differential equations is developed and implemented. A scalar function representing the infected population is defined on a…

Populations and Evolution · Quantitative Biology 2020-07-06 Sashikumaar Ganesan , Deepak Subramani

Epidemics have shaped human history, often with devastating consequences, motivating the development of mathematical models to understand and control their dynamics. Among the many aspects of epidemic behavior, the conditions that lead to…

Populations and Evolution · Quantitative Biology 2026-05-01 Germano Hartmann Brill , Pablo Enrique Jurado Silvestrin , Sebastian Gonçalves

For preventing the spread of epidemics such as the coronavirus disease COVID-19, social distancing and the isolation of infected persons are crucial. However, existing reaction-diffusion equations for epidemic spreading are incapable of…

Populations and Evolution · Quantitative Biology 2020-11-18 Michael te Vrugt , Jens Bickmann , Raphael Wittkowski

We present a modified diffusive epidemic process that has a finite threshold on scale-free graphs. The diffusive epidemic process describes the epidemic spreading in a non-sedentary population, and it is a reaction-diffusion process. In the…

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller

This paper is concerned with the spatio-temporal dynamics of an age-structured reaction-diffusion system of KPP-epidemic type (SIS), subject to Neumann boundary conditions and incorporating $L^1$ blow-up type death rate. We first establish…

Analysis of PDEs · Mathematics 2025-07-15 Cong-Bang Trang , Hoang-Hung Vo