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Statistical hypothesis tests typically use prespecified sample sizes, yet data often arrive sequentially. Interim analyses invalidate classical error guarantees, while existing sequential methods require rigid testing preschedules or incur…

Methodology · Statistics 2026-02-17 Chris Holmes , Stephen Walker

We propose a novel technique to boost the power of testing a high-dimensional vector $H:\btheta=0$ against sparse alternatives where the null hypothesis is violated only by a couple of components. Existing tests based on quadratic forms…

Methodology · Statistics 2014-08-19 Jianqing Fan , Yuan Liao , Jiawei Yao

The class of composite likelihood functions provides a flexible and powerful toolkit to carry out approximate inference for complex statistical models when the full likelihood is either impossible to specify or unfeasible to compute.…

Methodology · Statistics 2013-06-25 Nicola Lunardon , Elvezio Ronchetti

We derive a new class of statistical tests for generalized linear models based on thresholding point estimators. These tests can be employed whether the model includes more parameters than observations or not. For linear models, our tests…

Methodology · Statistics 2018-03-14 Sylvain Sardy , Caroline Giacobino , Jairo Diaz-Rodriguez

In this paper, we propose a general method for testing composite hypotheses. Our idea is to use confidence limits to define stopping and decision rules. The requirements of operating characteristic function can be satisfied by adjusting the…

Statistics Theory · Mathematics 2012-02-10 Xinjia Chen

In large scale genetic association studies, a primary aim is to test for association between genetic variants and a disease outcome. The variants of interest are often rare, and appear with low frequency among subjects. In this situation,…

Methodology · Statistics 2017-12-20 Arjun Sondhi , Kenneth Martin Rice

When applying multivariate extreme value statistics to analyze tail risk in compound events defined by a multivariate random vector, one often assumes that all dimensions share the same extreme value index. While such an assumption can be…

Methodology · Statistics 2026-02-16 Liujun Chen , Chen Zhou

Combining dependent p-values poses a long-standing challenge in statistical inference, particularly when aggregating findings from multiple methods to enhance signal detection. Recently, p-value combination tests based on regularly…

Methodology · Statistics 2025-04-22 Lin Gui , Yuchao Jiang , Jingshu Wang

The asymptotic expansion of the distribution of the gradient test statistic is derived for a composite hypothesis under a sequence of Pitman alternative hypotheses converging to the null hypothesis at rate $n^{-1/2}$, $n$ being the sample…

Statistics Theory · Mathematics 2015-03-17 Artur Lemonte , Silvia Ferrari

Power and sample size calculations for Wald tests in generalized linear models (GLMs) are often limited to specific cases like logistic regression. More general methods typically require detailed study parameters that are difficult to…

Methodology · Statistics 2026-01-21 Amy L Cochran , Shijie Yuan , Paul J Rathouz

In this article, we consider the problem of testing the independence between two random variables. Our primary objective is to develop tests that are highly effective at detecting associations arising from explicit or implicit functional…

Methodology · Statistics 2025-02-21 Seetharaman P , Sagnik Das , Angshuman Roy

The synthetic control method is often applied to problems with one treated unit and a small number of control units. A common inferential task in this setting is to test null hypotheses regarding the average treatment effect on the treated.…

Methodology · Statistics 2025-04-22 Lihua Lei , Timothy Sudijono

A popular framework for false discovery control is the random effects model in which the null hypotheses are assumed to be independent. This paper generalizes the random effects model to a conditional dependence model which allows…

Statistics Theory · Mathematics 2008-12-18 Wei Biao Wu

Several methods in survival analysis are based on the proportional hazards assumption. However, this assumption is very restrictive and often not justifiable in practice. Therefore, effect estimands that do not rely on the proportional…

Methodology · Statistics 2024-03-20 Merle Munko , Marc Ditzhaus , Dennis Dobler , Jon Genuneit

Fisherian randomization inference is often dismissed as testing an uninteresting and implausible hypothesis: the sharp null of no effects whatsoever. We show that this view is overly narrow. Many randomization tests are also valid under a…

Methodology · Statistics 2017-09-22 Devin Caughey , Allan Dafoe , Luke Miratrix

We consider a test for the hypothesis that the within-treatment variance component in a one-way random effects model is null. This test is based on a decomposition of a $U$-statistic. Its asymptotic null distribution is derived under the…

Statistics Theory · Mathematics 2008-12-18 Juvêncio S. Nobre , Julio M. Singer , Mervyn J. Silvapulle

Dose groups are compared with a control assuming an order restriction usually by the Williams trend test. Here, as an alternative, two variants of the closed testing procedure are considered, one where global Williams tests are used in the…

Applications · Statistics 2021-01-01 Ludwig A. Hothorn

We propose testing procedures for the hypothesis that a given set of discrete observations may be formulated as a particular time series of counts with a specific conditional law. The new test statistics incorporate the empirical…

Statistics Theory · Mathematics 2014-10-24 Šárka Hudecová , Marie Hušková , Simos G. Meintanis

Assume that we have a random sample from an absolutely continuous distribution (univariate, or multivariate) with a known functional form and some unknown parameters. In this paper, we have studied several parametric tests based on…

Statistics Theory · Mathematics 2024-05-14 Rahul Singh , Neeraj Misra

Generalizations to the permutation test are introduced to allow for situations in which the null model is not exchangeable. It is shown that the generalized permutation tests are exact, and a partial converse: that any test function that is…

Methodology · Statistics 2018-09-03 Jeffrey Roach , William Valdar
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