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Purpose: Apparent diffusion coefficient (ADC) maps derived from diffusion weighted (DWI) MRI provides functional measurements about the water molecules in tissues. However, DWI is time consuming and very susceptible to image artifacts,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Zach Eidex , Mojtaba Safari , Jacob Wynne , Richard L. J. Qiu , Tonghe Wang , David Viar Hernandez , Hui-Kuo Shu , Hui Mao , Xiaofeng Yang

Diffusion models face significant challenges when employed for large-scale medical image reconstruction in real practice such as 3D Computed Tomography (CT). Due to the demanding memory, time, and data requirements, it is difficult to train…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Bowen Song , Jason Hu , Zhaoxu Luo , Jeffrey A. Fessler , Liyue Shen

Iodinated contrast media is essential for dual-energy computed tomography (DECT) angiography. Previous studies show that iodinated contrast media may cause side effects, and the interruption of the supply chain in 2022 led to a severe…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qing Lyu , Josh Tan , Megan E. Lipford , Chuang Niu , Micheal E. Zapadka , Christopher M. Lack , Jonathan D. Clemente , Christopher T. Whitlow , Ge Wang

Contrast-enhanced computed tomography (CECT) is pivotal for highlighting tissue perfusion and vascularity, yet its clinical ubiquity is impeded by the invasive nature of contrast agents and radiation risks. While virtual contrast…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Zilong Li , Dongyang Li , Chenglong Ma , Zhan Feng , Dakai Jin , Junping Zhang , Hao Luo , Fan Wang , Hongming Shan

Recently, perceptual image compression has achieved significant advancements, delivering high visual quality at low bitrates for natural images. However, for screen content, existing methods often produce noticeable artifacts when…

Computer Vision and Pattern Recognition · Computer Science 2025-05-12 Tongda Xu , Jiahao Li , Bin Li , Yan Wang , Ya-Qin Zhang , Yan Lu

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Accurate PET imaging increasingly requires methods that support unconstrained detector layouts from walk-through designs to long-axial rings where gaps and open sides lead to severely undersampled sinograms. Instead of constraining the…

Machine Learning · Computer Science 2025-11-13 Rüveyda Yilmaz , Julian Thull , Johannes Stegmaier , Volkmar Schulz

Diffusion models achieve state-of-the-art image generation but remain computationally costly due to iterative denoising. Latent-space models like Stable Diffusion reduce overhead yet lose fine detail, while retrieval-augmented methods…

Machine Learning · Computer Science 2025-12-23 Bilal Faye , Hanane Azzag , Mustapha Lebbah

Recent advances in diffusion models have demonstrated exceptional performance in generative tasks across vari-ous fields. In positron emission tomography (PET), the reduction in tracer dose leads to information loss in sino-grams. Using…

Machine Learning · Computer Science 2024-11-11 Xingyu Ai , Bin Huang , Fang Chen , Liu Shi , Binxuan Li , Shaoyu Wang , Qiegen Liu

Myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT) is widely applied for the diagnosis of cardiovascular diseases. Reducing the dose of the injected tracer is essential for lowering the patient's…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Xiongchao Chen , Bo Zhou , Huidong Xie , Xueqi Guo , Qiong Liu , Albert J. Sinusas , Chi Liu

MedSAM, a medical foundation model derived from the SAM architecture, has demonstrated notable success across diverse medical domains. However, its clinical application faces two major challenges: the dependency on labor-intensive manual…

Image and Video Processing · Electrical Eng. & Systems 2025-04-17 Peng Huang , Shu Hu , Bo Peng , Xun Gong , Penghang Yin , Hongtu Zhu , Xi Wu , Xin Wang

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

The use of machine learning in fluid dynamics is becoming more common to expedite the computation when solving forward and inverse problems of partial differential equations. Yet, a notable challenge with existing convolutional neural…

Fluid Dynamics · Physics 2024-05-10 Siming Shan , Pengkai Wang , Song Chen , Jiaxu Liu , Chao Xu , Shengze Cai

Quantitative PET attenuation correction (AC) for combined cardiac PET/MR is a challenging problem. We propose and evaluate an AC approach that uses coincidences from a relatively weak and physically fixed sparse external source, in…

Medical Physics · Physics 2023-01-02 Mi-Ae Park , Vlad G. Zaha , Ramsey D. Badawi , Spencer L. Bowen

Objective: The study aims to address the challenge of aligning Standard Fundus Images (SFIs) and Ultra-Widefield Fundus Images (UWFIs), which is difficult due to their substantial differences in viewing range and the amorphous appearance of…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kanggeon Lee , Su Jeong Song , Soochahn Lee , Kyoung Mu Lee

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Histological artifacts pose challenges for both pathologists and Computer-Aided Diagnosis (CAD) systems, leading to errors in analysis. Current approaches for histological artifact restoration, based on Generative Adversarial Networks…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zhenqi He , Wenrui Liu , Minghao Yin , Kai Han

Deep convolutional neural networks (DCNN) have demonstrated its capability to convert MR image to pseudo CT for PET attenuation correction in PET/MRI. Conventionally, attenuated events are corrected in sinogram space using attenuation maps…

Computer Vision and Pattern Recognition · Computer Science 2019-05-22 Jaewon Yang , Dookun Park , Jae Ho Sohn , Zhen Jane Wang , Grant T. Gullberg , Youngho Seo

Generative artificial intelligence (AI) has been playing an important role in various domains. Leveraging its high capability to generate high-fidelity and diverse synthetic data, generative AI is widely applied in diagnostic tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Yifan Jiang , Ahmad Shariftabrizi , Venkata SK. Manem

Background: Photoacoustic Microscopy (PAM) integrates optical and acoustic imaging, offering enhanced penetration depth for detecting optical-absorbing components in tissues. Nonetheless, challenges arise in scanning large areas with high…

Medical Physics · Physics 2023-12-15 Irem Loc , Mehmet Burcin Unlu
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