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The development process of scientific applications is largely dependent on scientific progress and the experimental research results. Thus, dealing with frequent changes is one of the main problems faced by the developers of scientific…

Software Engineering · Computer Science 2014-05-09 Bojana Koteska , Anastas Misev

Brain tumors are a complex and potentially life-threatening medical condition that requires accurate diagnosis and timely treatment. In this paper, we present a machine learning-based system designed to assist healthcare professionals in…

Image and Video Processing · Electrical Eng. & Systems 2023-04-18 Belal Badawy , Romario Sameh Samir , Youssef Tarek , Mohammed Ahmed , Rana Ibrahim , Manar Ahmed , Mohamed Hassan

Civic grassroots have proven their ability to create useful and scalable software that addresses pressing social needs. Although software engineering plays a fundamental role in the process of creating civic technology, academic literature…

Software Engineering · Computer Science 2021-06-18 Antti Knutas , Victoria Palacin , Giovanni Maccani , Markus Helfert

Advances in large language models (LLMs) have encouraged their adoption in the healthcare domain where vital clinical information is often contained in unstructured notes. Cancer staging status is available in clinical reports, but it…

Computation and Language · Computer Science 2024-08-30 Chia-Hsuan Chang , Mary M. Lucas , Yeawon Lee , Christopher C. Yang , Grace Lu-Yao

Recently, there has been a resurgence of interest in rigorous algorithms for the inference of cancer progression from genomic data. The motivations are manifold: (i) growing NGS and single cell data from cancer patients, (ii) need for novel…

Machine Learning · Computer Science 2016-02-25 Daniele Ramazzotti

Model-based development is a widely-used method to describe complex systems that enables the rapid prototyping. Advances in the science of distributed systems has led to the development of large scale statechart models which are distributed…

Software Engineering · Computer Science 2018-01-23 Mohammad Hosseini , Richard Berlin , Lui Sha , Axel Terfloth , Houbing Song

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Xiaofei Wang , Hanyu Liu , Yupei Zhang , Boyang Zhao , Hao Duan , Wanming Hu , Yonggao Mou , Stephen Price , Chao Li

Cancer screening, leading to early detection, saves lives. Unfortunately, existing screening techniques require expensive and intrusive medical procedures, not globally available, resulting in too many lost would-be-saved lives. We present…

Machine Learning · Computer Science 2025-09-29 Liwen Sun , Hao-Ren Yao , Gary Gao , Ophir Frieder , Chenyan Xiong

In order to develop trustworthy healthcare artificial intelligence (AI) prospective and ergonomics studies that consider the complexity and reality of real-world applications of AI systems are needed. To achieve this, technology developers…

Computers and Society · Computer Science 2023-03-20 Nigel Rees , Kelly Holding , Mark Sujan

A large number of computational scientific research projects make use of open source software packages. However, the development process of such tools frequently differs from conventional software development; partly because of the nature…

Software Engineering · Computer Science 2013-09-24 Ivan Girotto , Axel Kohlmeyer , David Grellscheid , Shawn T. Brown

Secure and scalable data sharing is essential for collaborative clinical decision making. Conventional clinical data efforts are often siloed, however, which creates barriers to efficient information exchange and impedes effective treatment…

Computers and Society · Computer Science 2018-07-11 Peng Zhang , Jules White , Douglas C. Schmidt , Gunther Lenz , S. Trent Rosenbloom

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and…

Computation and Language · Computer Science 2024-10-08 Xueshen Li , Xinlong Hou , Nirupama Ravi , Ziyi Huang , Yu Gan

In open-source software development environments; textual, numerical and relationship-based data generated are of interest to researchers. Various data sets are available for this data, which is frequently used in areas such as software…

Software Engineering · Computer Science 2020-10-01 Abdulkadir Şeker , Banu Diri , Halil Arslan

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

The performance, reliability, cost, size and energy usage of computing systems can be improved by one or more orders of magnitude by the systematic use of modern control and optimization methods. Computing systems rely on the use of…

Systems and Control · Computer Science 2017-10-13 Eric C. Kerrigan

Software Engineering activities are information intensive. Research proposes Information Retrieval (IR) techniques to support engineers in their daily tasks, such as establishing and maintaining traceability links, fault identification, and…

Software Engineering · Computer Science 2023-08-24 Michael Unterkalmsteiner , Tony Gorschek , Robert Feldt , Niklas Lavesson

In this paper, we address the knowledge engineering problems for hypothesis generation motivated by applications that require timely exploration of hypotheses under unreliable observations. We looked at two applications: malware detection…

Artificial Intelligence · Computer Science 2014-08-29 Shirin Sohrabi , Octavian Udrea , Anton V. Riabov

The appearance of a new dangerous and contagious disease requires the development of a drug therapy faster than what is foreseen by usual mechanisms. Many drug therapy developments consist in investigating through different clinical trials…

Quantitative Methods · Quantitative Biology 2020-03-31 Ezequiel Alvarez , Federico Lamagna , Manuel Szewc

To bridge the digital skills gap, we need to train more people in Software Engineering techniques. This paper reports on a project exploring the way students solve tasks using collaborative development platforms and version control systems,…

Cancer is a complex disease driven by genomic alterations, and tumor sequencing is becoming a mainstay of clinical care for cancer patients. The emergence of multi-institution sequencing data presents a powerful resource for learning…

Genomics · Quantitative Biology 2024-10-31 Yuan Chen , Ronglai Shen , Xiwen Feng , Katherine Panageas